Henoch-Schönlein purpura history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The signs and symptoms of Henoch-Schönlein purpura (HSP) are skin lesions such as palpable [[purpura]], abdominal pain, [[melena]], bloody [[diarrhea]], [[hematemesis]], [[duodenal]] [[ulcers]], [[arthralgia]]. | |||
==History== | ==History== | ||
Obtaining history gives important information in making a diagnosis of HSP. It provides an insight into the cause, precipitating factors, and associated comorbid conditions. A complete history will help determine the correct therapy and helps in determining the [[prognosis]]. The areas of focus should be on onset, duration, and progression of [[symptoms]] such as | |||
==Symptoms== | ==Signs and Symptoms== | ||
* '''Skin'''- The skin lesions start as maculae progressing to papules and then to palpable purpura involving the symmetrical dependent areas such as buttocks, back, upper and lower limbs. | Clinical features of HSP:<ref name="pmid29438165">{{cite journal |vauthors=Louie CY, Gomez AJ, Sibley RK, Bass D, Longacre TA |title=Histologic Features of Gastrointestinal Tract Biopsies in IgA Vasculitis (Henoch-Schönlein Purpura) |journal=Am. J. Surg. Pathol. |volume=42 |issue=4 |pages=529–533 |date=April 2018 |pmid=29438165 |doi=10.1097/PAS.0000000000001036 |url=}}</ref><ref name="pmid18351468">{{cite journal |vauthors=Ebert EC |title=Gastrointestinal manifestations of Henoch-Schonlein Purpura |journal=Dig. Dis. Sci. |volume=53 |issue=8 |pages=2011–9 |date=August 2008 |pmid=18351468 |doi=10.1007/s10620-007-0147-0 |url=}}</ref><ref name="pmid28637108">{{cite journal |vauthors=Kim KY |title=[Henoch-Schönlein Purpura Presenting as Intussusception] |language=Korean |journal=Korean J Gastroenterol |volume=69 |issue=6 |pages=372–376 |date=June 2017 |pmid=28637108 |doi=10.4166/kjg.2017.69.6.372 |url=}}</ref><ref name="pmid19687709">{{cite journal |vauthors=Mannenbach MS, Reed AM, Moir C |title=Atypical presentation of Henoch-Schönlein purpura |journal=Pediatr Emerg Care |volume=25 |issue=8 |pages=513–5 |date=August 2009 |pmid=19687709 |doi=10.1097/PEC.0b013e3181b0a46f |url=}}</ref><ref name="pmid9767498">{{cite journal |vauthors=Choong CK, Beasley SW |title=Intra-abdominal manifestations of Henoch-Schönlein purpura |journal=J Paediatr Child Health |volume=34 |issue=5 |pages=405–9 |date=October 1998 |pmid=9767498 |doi= |url=}}</ref> | ||
** Other skin lesions include hives, angioedema, and target lesions. | * '''Skin'''- The skin lesions start as [[Macule|maculae]] progressing to papules and then to [[Purpura|palpable purpura]] involving the symmetrical dependent areas such as buttocks, back, upper and lower limbs. | ||
** Other skin lesions include [[hives]], [[angioedema]], and target lesions. | |||
* '''Gastrointestinal''' | * '''Gastrointestinal''' | ||
**Abdominal pain | **Abdominal pain | ||
**Melena | **[[Melena]] | ||
**Bloody diarrhea | **[[Bloody diarrhea]] | ||
**Hematemesis | **[[Hematemesis]] | ||
**Duodenal ulcers | **[[Duodenal ulcers]] | ||
**GI bleed | **[[GI bleeding|GI bleed]] | ||
* '''Joints''' | * '''Joints''' | ||
**Arthralgia is most common in the knees and ankles and rarely the interphalangeal joints and wrist. | **[[Arthralgia]] is most common in the knees and ankles and rarely the [[interphalangeal joints]] and wrist. | ||
==References== | ==References== | ||
Latest revision as of 20:20, 15 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The signs and symptoms of Henoch-Schönlein purpura (HSP) are skin lesions such as palpable purpura, abdominal pain, melena, bloody diarrhea, hematemesis, duodenal ulcers, arthralgia.
History
Obtaining history gives important information in making a diagnosis of HSP. It provides an insight into the cause, precipitating factors, and associated comorbid conditions. A complete history will help determine the correct therapy and helps in determining the prognosis. The areas of focus should be on onset, duration, and progression of symptoms such as
Signs and Symptoms
Clinical features of HSP:[1][2][3][4][5]
- Skin- The skin lesions start as maculae progressing to papules and then to palpable purpura involving the symmetrical dependent areas such as buttocks, back, upper and lower limbs.
- Other skin lesions include hives, angioedema, and target lesions.
- Gastrointestinal
- Abdominal pain
- Melena
- Bloody diarrhea
- Hematemesis
- Duodenal ulcers
- GI bleed
- Joints
- Arthralgia is most common in the knees and ankles and rarely the interphalangeal joints and wrist.
References
- ↑ Louie CY, Gomez AJ, Sibley RK, Bass D, Longacre TA (April 2018). "Histologic Features of Gastrointestinal Tract Biopsies in IgA Vasculitis (Henoch-Schönlein Purpura)". Am. J. Surg. Pathol. 42 (4): 529–533. doi:10.1097/PAS.0000000000001036. PMID 29438165.
- ↑ Ebert EC (August 2008). "Gastrointestinal manifestations of Henoch-Schonlein Purpura". Dig. Dis. Sci. 53 (8): 2011–9. doi:10.1007/s10620-007-0147-0. PMID 18351468.
- ↑ Kim KY (June 2017). "[Henoch-Schönlein Purpura Presenting as Intussusception]". Korean J Gastroenterol (in Korean). 69 (6): 372–376. doi:10.4166/kjg.2017.69.6.372. PMID 28637108.
- ↑ Mannenbach MS, Reed AM, Moir C (August 2009). "Atypical presentation of Henoch-Schönlein purpura". Pediatr Emerg Care. 25 (8): 513–5. doi:10.1097/PEC.0b013e3181b0a46f. PMID 19687709.
- ↑ Choong CK, Beasley SW (October 1998). "Intra-abdominal manifestations of Henoch-Schönlein purpura". J Paediatr Child Health. 34 (5): 405–9. PMID 9767498.