Adult-onset Still's disease historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
Adult-onset Still's disease is an inflammatory condition characterized by high spiking | Adult-onset Still's disease (AOSD) is an [[inflammatory]] condition characterized by high spiking [[fever]], [[rash]], [[sore throat]], and [[joint pain]]. In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him. In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA. There's no cure for adult-onset Still's disease; however, [[symptomatic]] treatment using [[corticosteroids]], anti-[[interleukin]] agents and [[Disease-modifying antirheumatic drug|disease modifying anti-rheumatic drugs]] ([[DMARDs]]) may provide relief, and aid in remission. | ||
==Historical Perspective== | ==Historical Perspective== | ||
* Adult-onset Still's disease is an inflammatory condition characterized by high spiking | * Adult-onset Still's disease is an [[inflammatory]] condition characterized by high spiking [[fever]], [[rash]], [[sore throat]], and [[joint pain]].<ref name="urlAdult Still disease: MedlinePlus Medical Encyclopedia">{{cite web |url=https://medlineplus.gov/ency/article/000450.htm |title=Adult Still disease: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref> | ||
* As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications. | * As it progresses, adult-onset Still's disease may lead to chronic [[arthritis]] and other complications. | ||
* In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.<ref name="urlWhat is Still’s Disease? | Stills Disease Information Center">{{cite web |url=http://www.stillsdisease.org/index.php/stills-info/ |title=What is Still’s Disease? | Still's Disease Information Center |format= |work= |accessdate=}}</ref> | * In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.<ref name="urlWhat is Still’s Disease? | Stills Disease Information Center">{{cite web |url=http://www.stillsdisease.org/index.php/stills-info/ |title=What is Still’s Disease? | Still's Disease Information Center |format= |work= |accessdate=}}</ref> | ||
* Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA). | * Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA). | ||
* In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.<ref name="pmid5315135">{{cite journal |vauthors=Bywaters EG |title=Still's disease in the adult |journal=Ann. Rheum. Dis. |volume=30 |issue=2 |pages=121–33 |date=March 1971 |pmid=5315135 |pmc=1005739 |doi= |url=}}</ref> | * In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.<ref name="pmid5315135">{{cite journal |vauthors=Bywaters EG |title=Still's disease in the adult |journal=Ann. Rheum. Dis. |volume=30 |issue=2 |pages=121–33 |date=March 1971 |pmid=5315135 |pmc=1005739 |doi= |url=}}</ref> | ||
* The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs) | * The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and [[infections]] ([[Pathogen-associated molecular pattern|pathogen-associated molecular patterns]]- [[Pathogen-associated molecular pattern|PAMPs]]) | ||
* There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission. | * There's no cure for adult-onset Still's disease; however, [[symptomatic]] treatment using [[corticosteroids]], anti-[[interleukin]] agents and [[Disease-modifying antirheumatic drug|disease modifying anti-rheumatic drugs]] ([[DMARDs]]) may provide relief, and aid in remission. | ||
==References== | ==References== | ||
Latest revision as of 04:41, 23 April 2018
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Adult-onset Still's disease |
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Differentiating Adult-onset Still’s Disease from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Template:Adult-onset Still's disease On the Web |
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American Roentgen Ray Society Images of Template:Adult-onset Still's disease |
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Template:Adult-onset Still's disease in the news |
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Risk calculators and risk factors for Template:Adult-onset Still's disease |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
Adult-onset Still's disease (AOSD) is an inflammatory condition characterized by high spiking fever, rash, sore throat, and joint pain. In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him. In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA. There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission.
Historical Perspective
- Adult-onset Still's disease is an inflammatory condition characterized by high spiking fever, rash, sore throat, and joint pain.[1]
- As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications.
- In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.[2]
- Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA).
- In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.[3]
- The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs)
- There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission.
References
- ↑ "Adult Still disease: MedlinePlus Medical Encyclopedia".
- ↑ "What is Still's Disease? | Still's Disease Information Center".
- ↑ Bywaters EG (March 1971). "Still's disease in the adult". Ann. Rheum. Dis. 30 (2): 121–33. PMC 1005739. PMID 5315135.