Undifferentiated connective tissue disease laboratory findings: Difference between revisions

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__NOTOC__
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{{Undifferentiated connective tissue disease}}
{{Undifferentiated connective tissue disease}}
{{CMG}} {{AE}}
{{CMG}} {{AE}}{{ADS}}


==Overview==
==Overview==
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
Laboratory findings suggestive of undifferentiated connective tissue disease include [[Leukopenia]],increased [[erythrocyte sedimentation rate]], [[C-reactive protein]], [[Antinuclear antibodies]], anti DNA antibodies, anti Ro/SSA antibodies, and anti-RNP antibodies
 
OR
 
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
 
OR
 
[Test] is usually normal for patients with [disease name].
 
OR
 
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
 
OR
 
There are no diagnostic laboratory findings associated with [disease name].


==Laboratory Findings==
==Laboratory Findings==
*Laboratory findings suggestive of undifferentiated connective tissue disease include:<ref name="pmid9694051">{{cite journal |vauthors=Danieli MG, Fraticelli P, Salvi A, Gabrielli A, Danieli G |title=Undifferentiated connective tissue disease: natural history and evolution into definite CTD assessed in 84 patients initially diagnosed as early UCTD |journal=Clin. Rheumatol. |volume=17 |issue=3 |pages=195–201 |date=1998 |pmid=9694051 |doi= |url=}}</ref><ref name="pmid17110308">{{cite journal |vauthors=Mosca M, Tani C, Neri C, Baldini C, Bombardieri S |title=Undifferentiated connective tissue diseases (UCTD) |journal=Autoimmun Rev |volume=6 |issue=1 |pages=1–4 |date=November 2006 |pmid=17110308 |doi=10.1016/j.autrev.2006.03.004 |url=}}</ref>
*Laboratory findings suggestive of undifferentiated connective tissue disease include:<ref name="pmid9694051">{{cite journal |vauthors=Danieli MG, Fraticelli P, Salvi A, Gabrielli A, Danieli G |title=Undifferentiated connective tissue disease: natural history and evolution into definite CTD assessed in 84 patients initially diagnosed as early UCTD |journal=Clin. Rheumatol. |volume=17 |issue=3 |pages=195–201 |date=1998 |pmid=9694051 |doi= |url=}}</ref><ref name="pmid17110308">{{cite journal |vauthors=Mosca M, Tani C, Neri C, Baldini C, Bombardieri S |title=Undifferentiated connective tissue diseases (UCTD) |journal=Autoimmun Rev |volume=6 |issue=1 |pages=1–4 |date=November 2006 |pmid=17110308 |doi=10.1016/j.autrev.2006.03.004 |url=}}</ref><ref name="pmid12846049">{{cite journal |vauthors=Bodolay E, Csiki Z, Szekanecz Z, Ben T, Kiss E, Zeher M, Szücs G, Dankó K, Szegedi G |title=Five-year follow-up of 665 Hungarian patients with undifferentiated connective tissue disease (UCTD) |journal=Clin. Exp. Rheumatol. |volume=21 |issue=3 |pages=313–20 |date=2003 |pmid=12846049 |doi= |url=}}</ref><ref name="pmid18328157">{{cite journal |vauthors=Ceribelli A, Cavazzana I, Franceschini F, Quinzanini M, Rizzini FL, Cattaneo R |title=Isotype switching and titer variation of anti-Ro/SSA antibodies over time in 100 patients with undifferentiated connective tissue disease (UCTD) |journal=Clin. Exp. Rheumatol. |volume=26 |issue=1 |pages=117–20 |date=2008 |pmid=18328157 |doi= |url=}}</ref><ref name="pmid24518855">{{cite journal |vauthors=Mosca M, Tani C, Vagnani S, Carli L, Bombardieri S |title=The diagnosis and classification of undifferentiated connective tissue diseases |journal=J. Autoimmun. |volume=48-49 |issue= |pages=50–2 |date=2014 |pmid=24518855 |doi=10.1016/j.jaut.2014.01.019 |url=}}</ref><ref name="pmid11875835">{{cite journal |vauthors=Bodolay E, Szegedi G |title=[Undifferentiated connective tissue disease: clinical and serological profile of 578 patients followed for five years: disease course, prognosis and therapy] |language=Hungarian |journal=Orv Hetil |volume=143 |issue=5 |pages=229–33 |date=February 2002 |pmid=11875835 |doi= |url=}}</ref><ref name="pmid11491495">{{cite journal |vauthors=Cavazzana I, Franceschini F, Belfiore N, Quinzanini M, Caporali R, Calzavara-Pinton P, Bettoni L, Brucato A, Cattaneo R, Montecucco C |title=Undifferentiated connective tissue disease with antibodies to Ro/SSa: clinical features and follow-up of 148 patients |journal=Clin. Exp. Rheumatol. |volume=19 |issue=4 |pages=403–9 |date=2001 |pmid=11491495 |doi= |url=}}</ref><ref name="LaczikSoltesz2014">{{cite journal|last1=Laczik|first1=R.|last2=Soltesz|first2=P.|last3=Szodoray|first3=P.|last4=Szekanecz|first4=Z.|last5=Kerekes|first5=G.|last6=Paragh|first6=G.|last7=Rajnavolgyi|first7=E.|last8=Abel|first8=G.|last9=Szegedi|first9=G.|last10=Bodolay|first10=E.|title=Impaired endothelial function in patients with undifferentiated connective tissue disease: a follow-up study|journal=Rheumatology|volume=53|issue=11|year=2014|pages=2035–2043|issn=1462-0324|doi=10.1093/rheumatology/keu236}}</ref>
**[[Leukopenia]]
**[[Erythrocyte Sedimentation Rate]]
**[[C-Reactive Protein]]
**[[Antinuclear antibodies]]
**[[Antinuclear antibodies]]
**Anti DNA antibodies
**Anti DNA antibodies

Latest revision as of 18:24, 30 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]

Overview

Laboratory findings suggestive of undifferentiated connective tissue disease include Leukopenia,increased erythrocyte sedimentation rate, C-reactive protein, Antinuclear antibodies, anti DNA antibodies, anti Ro/SSA antibodies, and anti-RNP antibodies

Laboratory Findings

References

  1. ↑ Danieli MG, Fraticelli P, Salvi A, Gabrielli A, Danieli G (1998). "Undifferentiated connective tissue disease: natural history and evolution into definite CTD assessed in 84 patients initially diagnosed as early UCTD". Clin. Rheumatol. 17 (3): 195–201. PMID 9694051.
  2. ↑ Mosca M, Tani C, Neri C, Baldini C, Bombardieri S (November 2006). "Undifferentiated connective tissue diseases (UCTD)". Autoimmun Rev. 6 (1): 1–4. doi:10.1016/j.autrev.2006.03.004. PMID 17110308.
  3. ↑ Bodolay E, Csiki Z, Szekanecz Z, Ben T, Kiss E, Zeher M, Szücs G, Dankó K, Szegedi G (2003). "Five-year follow-up of 665 Hungarian patients with undifferentiated connective tissue disease (UCTD)". Clin. Exp. Rheumatol. 21 (3): 313–20. PMID 12846049.
  4. ↑ Ceribelli A, Cavazzana I, Franceschini F, Quinzanini M, Rizzini FL, Cattaneo R (2008). "Isotype switching and titer variation of anti-Ro/SSA antibodies over time in 100 patients with undifferentiated connective tissue disease (UCTD)". Clin. Exp. Rheumatol. 26 (1): 117–20. PMID 18328157.
  5. ↑ Mosca M, Tani C, Vagnani S, Carli L, Bombardieri S (2014). "The diagnosis and classification of undifferentiated connective tissue diseases". J. Autoimmun. 48-49: 50–2. doi:10.1016/j.jaut.2014.01.019. PMID 24518855.
  6. ↑ Bodolay E, Szegedi G (February 2002). "[Undifferentiated connective tissue disease: clinical and serological profile of 578 patients followed for five years: disease course, prognosis and therapy]". Orv Hetil (in Hungarian). 143 (5): 229–33. PMID 11875835.
  7. ↑ Cavazzana I, Franceschini F, Belfiore N, Quinzanini M, Caporali R, Calzavara-Pinton P, Bettoni L, Brucato A, Cattaneo R, Montecucco C (2001). "Undifferentiated connective tissue disease with antibodies to Ro/SSa: clinical features and follow-up of 148 patients". Clin. Exp. Rheumatol. 19 (4): 403–9. PMID 11491495.
  8. ↑ Laczik, R.; Soltesz, P.; Szodoray, P.; Szekanecz, Z.; Kerekes, G.; Paragh, G.; Rajnavolgyi, E.; Abel, G.; Szegedi, G.; Bodolay, E. (2014). "Impaired endothelial function in patients with undifferentiated connective tissue disease: a follow-up study". Rheumatology. 53 (11): 2035–2043. doi:10.1093/rheumatology/keu236. ISSN 1462-0324.

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