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| __NOTOC__
| | #Redirect[[Nephritic syndrome#Historical Perspective]] |
| {{Nephritic syndrome}}
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| ==Overview==
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| The symptoms of [[glomerulonephritis]] were first described by Richard Bright in 1827 when he discovered that several patients died with generalized [[edema]] were found to have [[renal disease]].<ref>{{cite book | last = Bright | first = R | authorlink = | coauthors = | title = Reports of Medical Cases, Selected with a View of Illustrating the Symptoms and Cure of Diseases by a Reference to Morbid Anatomy, vol. I | publisher = Longmans | date = 1827-1831 | location = London | pages = | url = | doi = | id = | isbn = }}</ref> It was not until 1914 that Volhard and Fahr classified [[renal disease]]s in ''Die Brightsche Nierenkrankheit'' to 3 main categories: [[nephroses]], [[nephritis]], and arteriosclerotic disease.<ref>{{cite book | last = Volhard | first = F | authorlink = | coauthors = | title = Die Brightsche Nierenkrankheit | publisher = Springer | date = 1914 | location = | pages = | url = | doi = | id = | isbn = }}</ref> Acute post-streptococcal glomerulonephritis is thus considered the earliest nephritic syndrome to be described. In 1908, C.F. Wahrer described an epidemic of hemorrhagic nephritis preceded by [[scarlet fever]] in 35 patients. Epidemics of nephritis continued in 1915 among British troops during World War I.<ref name="pmid13052693">{{cite journal| author=RAMMELKAMP CH, WEAVER RS| title=Acute glomerulonephritis, the significance of the variations in the incidence of the disease. | journal=J Clin Invest | year= 1953 |volume= 32 | issue= 4 | pages= 345-58 | pmid=13052693 | doi=10.1172/JCI102745 | pmc=PMC438348 |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13052693 }} </ref> Clinical and pathological findings from both epidemics were similar. Hemolytic [[streptococci]] were isolated from cultures of the [[oropharynx]] in many patients.<ref name="pmid13052693">{{cite journal| author=RAMMELKAMP CH, WEAVER RS| title=Acute glomerulonephritis, the significance of the variations in the incidence of the disease. | journal=J Clin Invest | year= 1953 | volume= 32 | issue= 4 | pages= 345-58 | pmid=13052693 |doi=10.1172/JCI102745 | pmc=PMC438348 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13052693 }} </ref>
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| ==References==
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| {{reflist|2}}
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| {{WH}}
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| {{WS}}
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| [[Category:Disease]]
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| [[Category:Nephrology]]
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| [[Category:Syndromes]]
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| [[Category:Pediatrics]]
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