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==[[Myoglobinuria overview|Overview]]==
==[[Myoglobinuria overview|Overview]]==
[[Myoglobinuria]] is the presence of [[myoglobin]] in the urine, usually associated with [[rhabdomyolysis]] or muscle destruction.
*[[Myoglobin]] ('''Mb''' or '''MB''') is an [[iron- and oxygen-binding protein]] found in [[muscles]]. Myoglobin is present in [[muscle]] cells as a reserve of [[oxygen]].In humans, myoglobin is only found in the bloodstream after muscle injury. It is an abnormal finding, and can be diagnostically relevant when found in blood.<ref name=Nelson00>{{cite book | author = Nelson DL, Cox MM | title = Lehninger Principles of Biochemistry | publisher = Worth Publishers | location = New York | year = 2000 | page = 206 | edition = 3rd | isbn = 0-7167-6203-X | url=https://books.google.com/books?id=5Ek9J4p3NfkC&dq=nelson+2000+Lehninger+Principles+of+Biochemistry&q=myoglobin}} (Google books link is the 2008 edition)</ref>
*Myoglobin is the primary [[oxygen]]-carrying [[biological pigment|pigment]] of muscle tissues.<ref name="review">{{cite journal | vauthors = Ordway GA, Garry DJ | title = Myoglobin: an essential hemoprotein in striated muscle | journal = The Journal of Experimental Biology | volume = 207 | issue = Pt 20 | pages = 3441–6 | date = Sep 2004 | pmid = 15339940 | doi = 10.1242/jeb.01172 }}</ref> High concentrations of myoglobin in muscle cells allow organisms to hold their breath for a longer period of time. Diving mammals such as whales and seals have muscles with particularly high abundance of myoglobin.<ref name=Nelson00/> Myoglobin is found in Type I muscle, Type II A and Type II B, but most texts consider myoglobin not to be found in [[smooth muscle tissue|smooth muscle]].
==References==
{{Reflist|2}}
{{WH}}
{{WS}}
[[Category: (name of the system)]]


==[[Myoglobinuria historical perspective|Historical Perspective]]==
==[[Myoglobinuria historical perspective|Historical Perspective]]==
==References==
{{Reflist|2}}
{{WH}}
{{WS}}
[[Category: (name of the system)]]


==[[Myoglobinuria classification|Classification]]==
==[[Myoglobinuria classification|Classification]]==
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==[[Myoglobinuria pathophysiology|Pathophysiology]]==
==[[Myoglobinuria pathophysiology|Pathophysiology]]==


==[[Myoglobinuriacauses|Causes]]==
==[[Myoglobinuria causes|Causes]]==


==[[Myoglobinuria differential diagnosis|Differentiating Lead poisoning from other Diseases]]==
==[[Myoglobinuria differential diagnosis|Differentiating Myoglobinuria from other Diseases]]==


==[[Myoglobinuria epidemiology and demographics|Epidemiology and Demographics]]==
==[[Myoglobinuria epidemiology and demographics|Epidemiology and Demographics]]==

Latest revision as of 20:04, 15 August 2018

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Myoglobinuria
Model of helical domains in myoglobin.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.; Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]


Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Myoglobinuria from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies

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