Autoimmune hemolytic anemia MRI: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Autoimmune hemolytic anemia}} | {{Autoimmune hemolytic anemia}} | ||
{{CMG}} {{shyam}} | {{CMG}} {{shyam}}; {{AE}} [[User:Irfan Dotani|Irfan Dotani]] | ||
==Overview== | ==Overview== | ||
There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia, but MRI can be helpful in assessing for spleen size or iron overload. | There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia, but MRI can be helpful in assessing for [[spleen]] size or [[iron overload]]. | ||
==MRI== | ==MRI== | ||
There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia. However, MRI of the abdomen can be done to assess for other conditions related to autoimmune hemolytic anemia. | There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia. However, MRI of the abdomen can be done to assess for other conditions related to autoimmune hemolytic anemia. | ||
*'''Assessment for spleen size''': MRI of the abdomen can be done to assess for spleen size if there is concern about spleen enlargement. Spleen enlargement typically occurs in extravascular hemolysis. MRI is a more expensive diagnostic test than CT and should only be done if ultrasound or CT are contraindicated or nondiagnostic. For example, contraindications to CT scan include patients with known reaction to iodinated contrast, renal dysfunction, or concern about radiation exposure.<ref name="pmid23535191">{{cite journal| author=Linguraru MG, Sandberg JK, Jones EC, Summers RM| title=Assessing splenomegaly: automated volumetric analysis of the spleen. | journal=Acad Radiol | year= 2013 | volume= 20 | issue= 6 | pages= 675-84 | pmid=23535191 | doi=10.1016/j.acra.2013.01.011 | pmc=3945039 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23535191 }} </ref><ref name="pmid24377046">{{cite journal| author=Palas J, Matos AP, Ramalho M| title=The spleen revisited: an overview on magnetic resonance imaging. | journal=Radiol Res Pract | year= 2013 | volume= 2013 | issue= | pages= 219297 | pmid=24377046 | doi=10.1155/2013/219297 | pmc=3859258 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24377046 }} </ref> | *'''Assessment for spleen size''': | ||
*'''Assessment for iron overload''': Cardiac or hepatic MRI can also be done to assess for iron overload from frequent packed [[red blood cell]] transfusions. The T2 STAR sequence can assess specifically for iron overload in the heart and liver.<ref name="pmid25064711">{{cite journal| author=Wood JC| title=Use of magnetic resonance imaging to monitor iron overload. | journal=Hematol Oncol Clin North Am | year= 2014 | volume= 28 | issue= 4 | pages= 747-64, vii | pmid=25064711 | doi=10.1016/j.hoc.2014.04.002 | pmc=4115249 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25064711 }} </ref><ref name="pmid20355237">{{cite journal| author=Tziomalos K, Perifanis V| title=Liver iron content determination by magnetic resonance imaging. | journal=World J Gastroenterol | year= 2010 | volume= 16 | issue= 13 | pages= 1587-97 | pmid=20355237 | doi= | pmc=2848367 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20355237 }} </ref> | **MRI of the abdomen can be done to assess for [[spleen]] size if there is concern about spleen enlargement. | ||
**Spleen enlargement typically occurs in extravascular [[hemolysis]]. | |||
**MRI is a more expensive diagnostic test than CT and should only be done if ultrasound or CT are contraindicated or nondiagnostic. | |||
**For example, contraindications to CT scan include patients with known reaction to iodinated contrast, [[renal dysfunction]], or concern about radiation exposure.<ref name="pmid23535191">{{cite journal| author=Linguraru MG, Sandberg JK, Jones EC, Summers RM| title=Assessing splenomegaly: automated volumetric analysis of the spleen. | journal=Acad Radiol | year= 2013 | volume= 20 | issue= 6 | pages= 675-84 | pmid=23535191 | doi=10.1016/j.acra.2013.01.011 | pmc=3945039 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23535191 }} </ref><ref name="pmid24377046">{{cite journal| author=Palas J, Matos AP, Ramalho M| title=The spleen revisited: an overview on magnetic resonance imaging. | journal=Radiol Res Pract | year= 2013 | volume= 2013 | issue= | pages= 219297 | pmid=24377046 | doi=10.1155/2013/219297 | pmc=3859258 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24377046 }} </ref> | |||
*'''Assessment for iron overload''': | |||
**[[Cardiac]] or [[hepatic]] MRI can also be done to assess for iron overload from frequent packed [[red blood cell]] transfusions. | |||
**The T2 STAR sequence can assess specifically for iron overload in the [[heart]] and [[liver]].<ref name="pmid25064711">{{cite journal| author=Wood JC| title=Use of magnetic resonance imaging to monitor iron overload. | journal=Hematol Oncol Clin North Am | year= 2014 | volume= 28 | issue= 4 | pages= 747-64, vii | pmid=25064711 | doi=10.1016/j.hoc.2014.04.002 | pmc=4115249 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25064711 }} </ref><ref name="pmid20355237">{{cite journal| author=Tziomalos K, Perifanis V| title=Liver iron content determination by magnetic resonance imaging. | journal=World J Gastroenterol | year= 2010 | volume= 16 | issue= 13 | pages= 1587-97 | pmid=20355237 | doi= | pmc=2848367 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20355237 }} </ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 14:09, 17 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Irfan Dotani
Overview
There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia, but MRI can be helpful in assessing for spleen size or iron overload.
MRI
There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia. However, MRI of the abdomen can be done to assess for other conditions related to autoimmune hemolytic anemia.
- Assessment for spleen size:
- MRI of the abdomen can be done to assess for spleen size if there is concern about spleen enlargement.
- Spleen enlargement typically occurs in extravascular hemolysis.
- MRI is a more expensive diagnostic test than CT and should only be done if ultrasound or CT are contraindicated or nondiagnostic.
- For example, contraindications to CT scan include patients with known reaction to iodinated contrast, renal dysfunction, or concern about radiation exposure.[1][2]
- Assessment for iron overload:
References
- ↑ Linguraru MG, Sandberg JK, Jones EC, Summers RM (2013). "Assessing splenomegaly: automated volumetric analysis of the spleen". Acad Radiol. 20 (6): 675–84. doi:10.1016/j.acra.2013.01.011. PMC 3945039. PMID 23535191.
- ↑ Palas J, Matos AP, Ramalho M (2013). "The spleen revisited: an overview on magnetic resonance imaging". Radiol Res Pract. 2013: 219297. doi:10.1155/2013/219297. PMC 3859258. PMID 24377046.
- ↑ Wood JC (2014). "Use of magnetic resonance imaging to monitor iron overload". Hematol Oncol Clin North Am. 28 (4): 747–64, vii. doi:10.1016/j.hoc.2014.04.002. PMC 4115249. PMID 25064711.
- ↑ Tziomalos K, Perifanis V (2010). "Liver iron content determination by magnetic resonance imaging". World J Gastroenterol. 16 (13): 1587–97. PMC 2848367. PMID 20355237.