Thrombotic thrombocytopenic purpura physical examination: Difference between revisions
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{{Thrombotic thrombocytopenic purpura}} | {{Thrombotic thrombocytopenic purpura}} | ||
{{CMG}} {{AE}} {{S.G.}} | |||
==Overview== | ==Overview== | ||
The presence of fever, [[purpura]], [[petechia]]<nowiki/>e, [[paleness]] in [[physical examination]] is highly suggestive of TTP. | |||
== Physical Examination == | == Physical Examination == | ||
===Skin=== | ===Skin=== | ||
* [[Bruise|Bruising]] may be present even in mucous membrane called purpura | * [[Bruise|Bruising]] may be present even in [[Mucus|mucous]] [[membrane]] called [[purpura]] | ||
* Pinpoint dots on skin called petechiae | * Pinpoint dots on [[skin]] called [[Petechia|petechiae]] | ||
* Paleness | * [[Paleness]] | ||
* Jaundice | * [[Jaundice]] | ||
===Heart=== | |||
* [[Tachycardia]] | |||
* [[Dyspnea]] | |||
* [[Arrhythmia]] | |||
* Severe [[Complication (medicine)|complications]]; [[sudden cardiac death]], [[Myocardial infarctions|myocardial infarction]], [[cardiogenic shock]], [[heart failure]] | |||
===Neurologic=== | ===Neurologic=== | ||
* No abnormalities | * No [[abnormalities]] | ||
* Moderate signs; speech changes, confusion | * Moderate [[Medical sign|signs]] <ref name="pmid18637802">{{cite journal| author=Scully M, Yarranton H, Liesner R, Cavenagh J, Hunt B, Benjamin S et al.| title=Regional UK TTP registry: correlation with laboratory ADAMTS 13 analysis and clinical features. | journal=Br J Haematol | year= 2008 | volume= 142 | issue= 5 | pages= 819-26 | pmid=18637802 | doi=10.1111/j.1365-2141.2008.07276.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18637802 }}</ref>; [[speech]] changes, [[confusion]] | ||
* Severe involvement | * Severe involvement: focal [[Medical sign|signs]], [[seizure]], [[stroke]], [[coma]] | ||
'''<big>Renal</big>''' | '''<big>Renal</big>''' | ||
===Other=== | ===Other=== | ||
* Fever | * [[Fever]] | ||
====Urine==== | ====Urine==== | ||
Latest revision as of 12:20, 5 October 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
The presence of fever, purpura, petechiae, paleness in physical examination is highly suggestive of TTP.
Physical Examination
Skin
- Bruising may be present even in mucous membrane called purpura
- Pinpoint dots on skin called petechiae
- Paleness
- Jaundice
Heart
- Dyspnea
- Arrhythmia
- Severe complications; sudden cardiac death, myocardial infarction, cardiogenic shock, heart failure
Neurologic
- No abnormalities
- Moderate signs [1]; speech changes, confusion
- Severe involvement: focal signs, seizure, stroke, coma
Renal
Other
Urine
- Dark urine
References
- ↑ Scully M, Yarranton H, Liesner R, Cavenagh J, Hunt B, Benjamin S; et al. (2008). "Regional UK TTP registry: correlation with laboratory ADAMTS 13 analysis and clinical features". Br J Haematol. 142 (5): 819–26. doi:10.1111/j.1365-2141.2008.07276.x. PMID 18637802.