Enterovirus 68 medical therapy: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{CMG}} | |||
{{CMG}}; {{AE}} {{AL}} | |||
{{Enterovirus 68}} | {{Enterovirus 68}} | ||
==Overview== | ==Overview== | ||
There is no specific [[antiviral]] treatment indicated for EV-D68 infections. Most patients may be followed-up on an outpatient basis. Patients presenting with more severe disease may be hospitalized or even admitted to an intensive care unit for supportive management and [[mechanical ventilation]], if needed. | |||
==Medical Therapy== | ==Medical Therapy== | ||
===Treatment Regimen=== | |||
:* '''Enterovirus treatment'''<ref>{{cite book | last = Gilbert | first = David | title = The Sanford guide to antimicrobial therapy 2014 | publisher = Antimicrobial Therapy | location = Sperryville, Va | year = 2014 | isbn = 978-1930808782 }}</ref> | |||
:::* Preferred regimen: supportive therapy<small><small><ref name="cdc">{{cite web| url=http://www.cdc.gov/non-polio-enterovirus/about/prevention-treatment.html| title= CDC Non-Polio Enterovirus Prevention & Treatment}} </ref><ref name="Abzug2014">{{cite journal|last1=Abzug|first1=Mark J.|title=The enteroviruses: Problems in need of treatments|journal=Journal of Infection|volume=68|year=2014|pages=S108–S114|issn=01634453|doi=10.1016/j.jinf.2013.09.020}}</ref></small></small> | |||
:::* Note (1): There is no specific [[antiviral]] therapy indicated in patients with EV-D68 infection. | |||
:::* Note (2): Most patients with uncomplicated disease may be followed-up on an outpatient basis. | |||
:::* Note (3): Patients with a complicated course or severe clinical disease may be hospitalized and admitted to the regular floor or even to the [[intensive care unit]]. | |||
:::* Note (4): Treatment is aimed at supportive care and prevention of [[Complication (medicine)|complications]]. | |||
:::* Note (5): Severe cases might require [[oxygen]] supplementation or [[mechanical ventilation]], as needed. | |||
:::* Note (6): A new drug [[Pleconaril]] designed to affect [[Rhinovirus]] is being suggested to be effective against Enterovirus D68 but further investigation is required<ref name="pmid25554786">{{cite journal| author=Liu Y, Sheng J, Fokine A, Meng G, Shin WH, Long F et al.| title=Structure and inhibition of EV-D68, a virus that causes respiratory illness in children. | journal=Science | year= 2015 | volume= 347 | issue= 6217 | pages= 71-4 | pmid=25554786 | doi=10.1126/science.1261962 | pmc=PMC4307789 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25554786 }} </ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Picornaviruses]] | [[Category:Picornaviruses]] | ||
[[Category:Enterovirus]] | [[Category:Enterovirus]] | ||
[[Category:Infectious Diseases]] | [[Category:Infectious Diseases]] | ||
[[Category: Infectious Disease Project]] | |||
Latest revision as of 15:30, 1 November 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
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Overview
There is no specific antiviral treatment indicated for EV-D68 infections. Most patients may be followed-up on an outpatient basis. Patients presenting with more severe disease may be hospitalized or even admitted to an intensive care unit for supportive management and mechanical ventilation, if needed.
Medical Therapy
Treatment Regimen
- Enterovirus treatment[1]
- Preferred regimen: supportive therapy[2][3]
- Note (1): There is no specific antiviral therapy indicated in patients with EV-D68 infection.
- Note (2): Most patients with uncomplicated disease may be followed-up on an outpatient basis.
- Note (3): Patients with a complicated course or severe clinical disease may be hospitalized and admitted to the regular floor or even to the intensive care unit.
- Note (4): Treatment is aimed at supportive care and prevention of complications.
- Note (5): Severe cases might require oxygen supplementation or mechanical ventilation, as needed.
- Note (6): A new drug Pleconaril designed to affect Rhinovirus is being suggested to be effective against Enterovirus D68 but further investigation is required[4]
References
- ↑ Gilbert, David (2014). The Sanford guide to antimicrobial therapy 2014. Sperryville, Va: Antimicrobial Therapy. ISBN 978-1930808782.
- ↑ "CDC Non-Polio Enterovirus Prevention & Treatment".
- ↑ Abzug, Mark J. (2014). "The enteroviruses: Problems in need of treatments". Journal of Infection. 68: S108–S114. doi:10.1016/j.jinf.2013.09.020. ISSN 0163-4453.
- ↑ Liu Y, Sheng J, Fokine A, Meng G, Shin WH, Long F; et al. (2015). "Structure and inhibition of EV-D68, a virus that causes respiratory illness in children". Science. 347 (6217): 71–4. doi:10.1126/science.1261962. PMC 4307789. PMID 25554786.