Renal cell carcinoma history and symptoms: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
 
(15 intermediate revisions by the same user not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{CMG}}
{{Renal cell carcinoma}}
{{Renal cell carcinoma}}


{{CMG}} {{AE}} {{F.K}}
==Overview==
==Overview==
The common symptoms of renal cell carcinoma include [[hematuria]], [[flank pain]], palpable [[abdominal mass]], [[hypertension]], [[hypercalcemia]], [[flushing]], [[fever]], [[fatigue]], [[weight loss]], [[anorexia]], and [[muscle atrophy]].
Common symptoms of renal cell carcinoma include [[hematuria]], [[flank pain]], palpable [[abdominal mass]],[[weight loss]] and [[anorexia]].


==Symptoms==
==History and Symptoms==
Patients with renal cell carcinoma typically present at 60-70 years of age. The most common diagnosis of renal cell carcinoma is based on the incidental finding; whereby most patients are asymptomatic.
Common symptoms of renal cell carcinoma include [[hematuria]], [[flank pain]], palpable [[abdominal mass]],[[weight loss]] and [[anorexia]].
Symptoms are often classified as local and systemic.
===Common Symptoms===
===Local Symptoms===
Common symptoms of renal cell carcinoma include:<ref name="pmid22112490">{{cite journal |vauthors=Cairns P |title=Renal cell carcinoma |journal=Cancer Biomark |volume=9 |issue=1-6 |pages=461–73 |date=2010 |pmid=22112490 |pmc=3308682 |doi=10.3233/CBM-2011-0176 |url=}}</ref><ref name="pmid788291">{{cite journal |vauthors=Gibbons RP, Monte JE, Correa RJ, Mason JT |title=Manifestations of renal cell carcinoma |journal=Urology |volume=8 |issue=3 |pages=201–6 |date=September 1976 |pmid=788291 |doi= |url=}}</ref><ref name="pmid5125665">{{cite journal |vauthors=Skinner DG, Colvin RB, Vermillion CD, Pfister RC, Leadbetter WF |title=Diagnosis and management of renal cell carcinoma. A clinical and pathologic study of 309 cases |journal=Cancer |volume=28 |issue=5 |pages=1165–77 |date=November 1971 |pmid=5125665 |doi= |url=}}</ref>
The presence of local signs is considered a poor prognostic marker<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref>. Common local symptoms are listed below<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref>:
*[[Hematuria]]
*[[Hematuria]]
*[[Flank pain]]
*Flank pain
*Palpable [[abdominal mass]]
*Palpable abdominal mass
===Systemic Symptoms===
The presence of systemic symptoms is mostly due to the presence of a [[paraneoplastic syndrome]], mostly due to the presence of parathyroid-related protein (PTHrp) or a [[metastasis]].<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref> Common systemic symptoms are listed below<ref name="pmid19269025">{{cite journal| author=Rini BI, Campbell SC, Escudier B| title=Renal cell carcinoma. | journal=Lancet | year= 2009 | volume= 373 | issue= 9669 | pages= 1119-32 | pmid=19269025 | doi=10.1016/S0140-6736(09)60229-4 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19269025  }} </ref>:
*[[Hypertension]] ([[renin]] secretion)
*[[Hypertension]] ([[renin]] secretion)
*[[Hypercalcemia]] (PTHrp secretion)
*[[Flushing]] (Erythroprotein secretion)
*[[Fever]]
*[[Fatigue]]
*[[Fatigue]]
*[[Weight loss]]
*[[Weight loss]]
*[[Anorexia]]
*[[Anorexia]]
===Less Common Symptoms===
Less common symptoms of renal cell carcinoma include:<ref name="pmid4751965">{{cite journal |vauthors=Cranston WI, Luff RH, Owen D, Rawlins MD |title=Studies on the pathogenesis of fever in renal carcinoma |journal=Clin Sci Mol Med |volume=45 |issue=4 |pages=459–67 |date=October 1973 |pmid=4751965 |doi= |url=}}</ref><ref name="pmid14260201">{{cite journal |vauthors=LYTTON B, ROSOF B, EVANS JS |title=PARATHYROID HORMONE-LIKE ACTIVITY IN A RENAL CARCINOMA PRODUCING HYPERCALCEMIA |journal=J. Urol. |volume=93 |issue= |pages=127–31 |date=February 1965 |pmid=14260201 |doi= |url=}}</ref><ref name="pmid7769125">{{cite journal |vauthors=de la Mata J, Uy HL, Guise TA, Story B, Boyce BF, Mundy GR, Roodman GD |title=Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo |journal=J. Clin. Invest. |volume=95 |issue=6 |pages=2846–52 |date=June 1995 |pmid=7769125 |pmc=295971 |doi=10.1172/JCI117990 |url=}}</ref>
*[[Fever]]
*[[Muscle atrophy]]
*[[Muscle atrophy]]
*
*[[Flushing]] (Erythroprotein secretion)
==History and Symptoms==
*[[Hypercalcemia]] (PTHrp secretion)
*The majority of patients with [disease name] are asymptomatic.
*Night sweats
OR
*[[Malaise]]
*The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
*[[Varicocele]]
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
===History===
Patients with [disease name]] may have a positive history of:
*[History finding 1]
*[History finding 2]
*[History finding 3]
===Common Symptoms===
Common symptoms of [disease] include:
*Hematuria
*Flank pain
*Palpable abdominal mass


===Less Common Symptoms===
Less common symptoms of [disease name] include
*[Symptom 1]
*[Symptom 2]
*[Symptom 3]
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 16:41, 11 December 2018

Renal cell carcinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Renal cell carcinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural history, Complications and Prognosis

Diagnosis

Staging

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Renal cell carcinoma history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Renal cell carcinoma history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Renal cell carcinoma history and symptoms

CDC on Renal cell carcinoma history and symptoms

Renal cell carcinoma history and symptoms in the news

Blogs on Renal cell carcinoma history and symptoms

Directions to Hospitals Treating Renal cell carcinoma

Risk calculators and risk factors for Renal cell carcinoma history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Overview

Common symptoms of renal cell carcinoma include hematuria, flank pain, palpable abdominal mass,weight loss and anorexia.

History and Symptoms

Common symptoms of renal cell carcinoma include hematuria, flank pain, palpable abdominal mass,weight loss and anorexia.

Common Symptoms

Common symptoms of renal cell carcinoma include:[1][2][3]

Less Common Symptoms

Less common symptoms of renal cell carcinoma include:[4][5][6]

References

  1. ↑ Cairns P (2010). "Renal cell carcinoma". Cancer Biomark. 9 (1–6): 461–73. doi:10.3233/CBM-2011-0176. PMC 3308682. PMID 22112490.
  2. ↑ Gibbons RP, Monte JE, Correa RJ, Mason JT (September 1976). "Manifestations of renal cell carcinoma". Urology. 8 (3): 201–6. PMID 788291.
  3. ↑ Skinner DG, Colvin RB, Vermillion CD, Pfister RC, Leadbetter WF (November 1971). "Diagnosis and management of renal cell carcinoma. A clinical and pathologic study of 309 cases". Cancer. 28 (5): 1165–77. PMID 5125665.
  4. ↑ Cranston WI, Luff RH, Owen D, Rawlins MD (October 1973). "Studies on the pathogenesis of fever in renal carcinoma". Clin Sci Mol Med. 45 (4): 459–67. PMID 4751965.
  5. ↑ LYTTON B, ROSOF B, EVANS JS (February 1965). "PARATHYROID HORMONE-LIKE ACTIVITY IN A RENAL CARCINOMA PRODUCING HYPERCALCEMIA". J. Urol. 93: 127–31. PMID 14260201.
  6. ↑ de la Mata J, Uy HL, Guise TA, Story B, Boyce BF, Mundy GR, Roodman GD (June 1995). "Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo". J. Clin. Invest. 95 (6): 2846–52. doi:10.1172/JCI117990. PMC 295971. PMID 7769125.
Retrieved from "https://www.wikidoc.org/index.php?title=Renal_cell_carcinoma_history_and_symptoms&oldid=1508268"