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__NOTOC__
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{{Lymphomatoid granulomatosis}}
{{Lymphomatoid granulomatosis}}
{{CMG}}; {{AE}} {{Kakbar}}
==Overview==
==Overview==
The most common symptoms of Lymphomatoid granulomatosis include Cough, Dyspnea, and Chest tightness. Patients may present with Cutaneous and/or CNS symptoms in some cases.
The most common symptoms of Lymphomatoid granulomatosis include cough, dyspnea, and chest tightness. Patients may present with cutaneous and/or CNS symptoms in some cases.
==History and Symptoms==
==History and Symptoms==
Symptoms of Lymphmatoid granulomatosis include Cough, Dyspnea, and Chest tightness. 
Symptoms of Lymphmatoid granulomatosis include [[Cough]], [[Dyspnea]], and [[Chest pain|Chest tightness]]. 
===History===
===History===
Patients with Lymphomatoid granulomatosis may have a positive history of:
Patients with Lymphomatoid granulomatosis may have a positive history of:
*EBV infection<ref name="pmid25321327">{{cite journal| author=Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L et al.| title=Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations. | journal=Am J Surg Pathol | year= 2015 | volume= 39 | issue= 2 | pages= 141-56 | pmid=25321327 | doi=10.1097/PAS.0000000000000328 | pmc=4293220 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25321327  }} </ref>
*[[Epstein Barr virus|EBV]] infection<ref name="pmid25321327">{{cite journal| author=Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L et al.| title=Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations. | journal=Am J Surg Pathol | year= 2015 | volume= 39 | issue= 2 | pages= 141-56 | pmid=25321327 | doi=10.1097/PAS.0000000000000328 | pmc=4293220 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25321327  }} </ref>
*Immunosuppression<ref name="pmid25022612">{{cite journal| author=Connors W, Griffiths C, Patel J, Belletrutti PJ| title=Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. | journal=BMC Gastroenterol | year= 2014 | volume= 14 | issue=  | pages= 127 | pmid=25022612 | doi=10.1186/1471-230X-14-127 | pmc=4105046 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25022612  }} </ref>
*[[Immunosuppression]]<ref name="pmid25022612">{{cite journal| author=Connors W, Griffiths C, Patel J, Belletrutti PJ| title=Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. | journal=BMC Gastroenterol | year= 2014 | volume= 14 | issue=  | pages= 127 | pmid=25022612 | doi=10.1186/1471-230X-14-127 | pmc=4105046 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25022612  }} </ref>
*HIV infection<ref name="pmid28824078">{{cite journal| author=Kano Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K et al.| title=The Complete Remission of Acquired Immunodeficiency Syndrome-associated Isolated Central Nervous System Lymphomatoid Granulomatosis: A Case Report and Review of the Literature. | journal=Intern Med | year= 2017 | volume= 56 | issue= 18 | pages= 2497-2501 | pmid=28824078 | doi=10.2169/internalmedicine.8776-16 | pmc=5643181 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28824078  }} </ref>
*[[HIV AIDS|HIV infection]]<ref name="pmid28824078">{{cite journal| author=Kano Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K et al.| title=The Complete Remission of Acquired Immunodeficiency Syndrome-associated Isolated Central Nervous System Lymphomatoid Granulomatosis: A Case Report and Review of the Literature. | journal=Intern Med | year= 2017 | volume= 56 | issue= 18 | pages= 2497-2501 | pmid=28824078 | doi=10.2169/internalmedicine.8776-16 | pmc=5643181 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28824078  }} </ref>
===Common Symptoms===
===Common Symptoms===
Common symptoms of [disease] include:
Common symptoms of [disease] include:
*Cough<ref name="pmid26631890">{{cite journal| author=Xu B, Liu H, Wang B, Zhang H, Wu H, Jin R et al.| title=Fever, Dry Cough and Exertional Dyspnea: Pulmonary Lymphomatoid Granulomatosis Masquerading as Pneumonia, Granulomatosis with Polyangiitis and Infectious Mononucleosis. | journal=Intern Med | year= 2015 | volume= 54 | issue= 23 | pages= 3045-9 | pmid=26631890 | doi=10.2169/internalmedicine.54.4822 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26631890  }} </ref><ref name="pmid25163591">{{cite journal| author=Ameli F, Ghafourian F, Masir N| title=Systematic Epstein-Barr virus-positive T-cell lymphoproliferative disease presenting as a persistent fever and cough: a case report. | journal=J Med Case Rep | year= 2014 | volume= 8 | issue=  | pages= 288 | pmid=25163591 | doi=10.1186/1752-1947-8-288 | pmc=4150421 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25163591  }} </ref>
*[[Cough]]<ref name="pmid26631890">{{cite journal| author=Xu B, Liu H, Wang B, Zhang H, Wu H, Jin R et al.| title=Fever, Dry Cough and Exertional Dyspnea: Pulmonary Lymphomatoid Granulomatosis Masquerading as Pneumonia, Granulomatosis with Polyangiitis and Infectious Mononucleosis. | journal=Intern Med | year= 2015 | volume= 54 | issue= 23 | pages= 3045-9 | pmid=26631890 | doi=10.2169/internalmedicine.54.4822 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26631890  }} </ref><ref name="pmid25163591">{{cite journal| author=Ameli F, Ghafourian F, Masir N| title=Systematic Epstein-Barr virus-positive T-cell lymphoproliferative disease presenting as a persistent fever and cough: a case report. | journal=J Med Case Rep | year= 2014 | volume= 8 | issue=  | pages= 288 | pmid=25163591 | doi=10.1186/1752-1947-8-288 | pmc=4150421 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25163591  }} </ref>
*Dyspnea<ref name="pmid21968985">{{cite journal| author=Olusina D, Ezemba N, Nzegwu MA| title=Pulmonary Lymphomatoid Granulomatosis: Report of A Case and Review of Literature. | journal=Niger Med J | year= 2011 | volume= 52 | issue= 1 | pages= 60-63 | pmid=21968985 | doi= | pmc=3180752 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21968985  }} </ref>
*[[Dyspnea]]<ref name="pmid21968985">{{cite journal| author=Olusina D, Ezemba N, Nzegwu MA| title=Pulmonary Lymphomatoid Granulomatosis: Report of A Case and Review of Literature. | journal=Niger Med J | year= 2011 | volume= 52 | issue= 1 | pages= 60-63 | pmid=21968985 | doi= | pmc=3180752 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21968985  }} </ref>
*Chest tightness<ref name="pmid26966605">{{cite journal| author=O'Brien S, Schmidt P| title=Lymphomatoid Granulomatosis with Paraneoplastic Polymyositis: A Rare Malignancy with Rare Complication. | journal=Case Rep Rheumatol | year= 2016 | volume= 2016 | issue=  | pages= 8242597 | pmid=26966605 | doi=10.1155/2016/8242597 | pmc=4757691 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26966605  }} </ref>
*[[Chest pain|Chest tightness]]<ref name="pmid26966605">{{cite journal| author=O'Brien S, Schmidt P| title=Lymphomatoid Granulomatosis with Paraneoplastic Polymyositis: A Rare Malignancy with Rare Complication. | journal=Case Rep Rheumatol | year= 2016 | volume= 2016 | issue=  | pages= 8242597 | pmid=26966605 | doi=10.1155/2016/8242597 | pmc=4757691 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26966605  }} </ref>
===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of Lymphomatoid granulomatosis  include <ref name="pmid26966605">{{cite journal| author=O'Brien S, Schmidt P| title=Lymphomatoid Granulomatosis with Paraneoplastic Polymyositis: A Rare Malignancy with Rare Complication. | journal=Case Rep Rheumatol | year= 2016 | volume= 2016 | issue=  | pages= 8242597 | pmid=26966605 | doi=10.1155/2016/8242597 | pmc=4757691 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26966605  }} </ref><ref name="pmid25535225">{{cite journal| author=Olmes DG, Agaimy A, Kloska S, Linker RA| title=Fatal lymphomatoid granulomatosis with primary CNS-involvement in an immunocompetent 80-year-old woman. | journal=BMJ Case Rep | year= 2014 | volume= 2014 | issue=  | pages=  | pmid=25535225 | doi=10.1136/bcr-2014-206825 | pmc=4275695 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25535225  }} </ref>
Less common symptoms of Lymphomatoid granulomatosis  include <ref name="pmid26966605">{{cite journal| author=O'Brien S, Schmidt P| title=Lymphomatoid Granulomatosis with Paraneoplastic Polymyositis: A Rare Malignancy with Rare Complication. | journal=Case Rep Rheumatol | year= 2016 | volume= 2016 | issue=  | pages= 8242597 | pmid=26966605 | doi=10.1155/2016/8242597 | pmc=4757691 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26966605  }} </ref><ref name="pmid25535225">{{cite journal| author=Olmes DG, Agaimy A, Kloska S, Linker RA| title=Fatal lymphomatoid granulomatosis with primary CNS-involvement in an immunocompetent 80-year-old woman. | journal=BMJ Case Rep | year= 2014 | volume= 2014 | issue=  | pages=  | pmid=25535225 | doi=10.1136/bcr-2014-206825 | pmc=4275695 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25535225  }} </ref>
<ref name="CostiniukKaramchandani2018">{{cite journal|last1=Costiniuk|first1=Cecilia T.|last2=Karamchandani|first2=Jason|last3=Bessissow|first3=Ali|last4=Routy|first4=Jean-Pierre|last5=Szabo|first5=Jason|last6=Frenette|first6=Charles|title=Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report|journal=BMC Infectious Diseases|volume=18|issue=1|year=2018|issn=1471-2334|doi=10.1186/s12879-018-3128-3}}</ref>
<ref name="CostiniukKaramchandani2018">{{cite journal|last1=Costiniuk|first1=Cecilia T.|last2=Karamchandani|first2=Jason|last3=Bessissow|first3=Ali|last4=Routy|first4=Jean-Pierre|last5=Szabo|first5=Jason|last6=Frenette|first6=Charles|title=Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report|journal=BMC Infectious Diseases|volume=18|issue=1|year=2018|issn=1471-2334|doi=10.1186/s12879-018-3128-3}}</ref><ref name="pmid20672711">{{cite journal| author=Halvani A, Owlia MB, Sami R| title=Lymphomatoid granulomatosis with splenomegaly and pancytopenia. | journal=Zhongguo Fei Ai Za Zhi | year= 2010 | volume= 13 | issue= 1 | pages= 84-6 | pmid=20672711 | doi=10.3779/j.issn.1009-3419.2010.01.17 | pmc=6000673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20672711  }} </ref>
*Malaise
*[[Malaise]]
*Weight loss
*[[Weight loss]]
*Fatigue
*[[Fatigue]]
*Fever
*[[Fever]]
CNS Symptoms<ref name="pmid29635846">{{cite journal| author=Kim JY, Jung KC, Park SH, Choe JY, Kim JE| title=Primary lymphomatoid granulomatosis in the central nervous system: A report of three cases. | journal=Neuropathology | year= 2018 | volume=  | issue=  | pages=  | pmid=29635846 | doi=10.1111/neup.12467 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29635846  }} </ref><ref name="pmid28824078">{{cite journal| author=Kano Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K et al.| title=The Complete Remission of Acquired Immunodeficiency Syndrome-associated Isolated Central Nervous System Lymphomatoid Granulomatosis: A Case Report and Review of the Literature. | journal=Intern Med | year= 2017 | volume= 56 | issue= 18 | pages= 2497-2501 | pmid=28824078 | doi=10.2169/internalmedicine.8776-16 | pmc=5643181 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28824078  }} </ref><ref name="pmid27656321">{{cite journal| author=Quinones E, Potes LI, Silva N, Lobato-Polo J| title=Lymphomatoid granulomatosis of the brain: A case report. | journal=Surg Neurol Int | year= 2016 | volume= 7 | issue= Suppl 23 | pages= S612-6 | pmid=27656321 | doi=10.4103/2152-7806.189732 | pmc=5025951 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27656321  }} </ref><ref name="pmid20672711">{{cite journal| author=Halvani A, Owlia MB, Sami R| title=Lymphomatoid granulomatosis with splenomegaly and pancytopenia. | journal=Zhongguo Fei Ai Za Zhi | year= 2010 | volume= 13 | issue= 1 | pages= 84-6 | pmid=20672711 | doi=10.3779/j.issn.1009-3419.2010.01.17 | pmc=6000673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20672711  }} </ref>  
CNS Symptoms<ref name="pmid29635846">{{cite journal| author=Kim JY, Jung KC, Park SH, Choe JY, Kim JE| title=Primary lymphomatoid granulomatosis in the central nervous system: A report of three cases. | journal=Neuropathology | year= 2018 | volume=  | issue=  | pages=  | pmid=29635846 | doi=10.1111/neup.12467 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29635846  }} </ref><ref name="pmid28824078">{{cite journal| author=Kano Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K et al.| title=The Complete Remission of Acquired Immunodeficiency Syndrome-associated Isolated Central Nervous System Lymphomatoid Granulomatosis: A Case Report and Review of the Literature. | journal=Intern Med | year= 2017 | volume= 56 | issue= 18 | pages= 2497-2501 | pmid=28824078 | doi=10.2169/internalmedicine.8776-16 | pmc=5643181 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28824078  }} </ref><ref name="pmid27656321">{{cite journal| author=Quinones E, Potes LI, Silva N, Lobato-Polo J| title=Lymphomatoid granulomatosis of the brain: A case report. | journal=Surg Neurol Int | year= 2016 | volume= 7 | issue= Suppl 23 | pages= S612-6 | pmid=27656321 | doi=10.4103/2152-7806.189732 | pmc=5025951 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27656321  }} </ref><ref name="pmid20672711">{{cite journal| author=Halvani A, Owlia MB, Sami R| title=Lymphomatoid granulomatosis with splenomegaly and pancytopenia. | journal=Zhongguo Fei Ai Za Zhi | year= 2010 | volume= 13 | issue= 1 | pages= 84-6 | pmid=20672711 | doi=10.3779/j.issn.1009-3419.2010.01.17 | pmc=6000673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20672711  }} </ref>  
*Headaches
*[[Headache|Headaches]]
*Seizures
*[[Seizure|Seizures]]
*Hemiparesis
*[[Hemiparesis]]
*Ataxia
*[[Ataxia]]
Cutaneous Symptoms<ref name="pmid20672711">{{cite journal| author=Halvani A, Owlia MB, Sami R| title=Lymphomatoid granulomatosis with splenomegaly and pancytopenia. | journal=Zhongguo Fei Ai Za Zhi | year= 2010 | volume= 13 | issue= 1 | pages= 84-6 | pmid=20672711 | doi=10.3779/j.issn.1009-3419.2010.01.17 | pmc=6000673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20672711  }} </ref><ref name="pmid25355540">{{cite journal| author=Rysgaard CD, Stone MS| title=Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature. | journal=J Cutan Pathol | year= 2015 | volume= 42 | issue= 3 | pages= 188-93 | pmid=25355540 | doi=10.1111/cup.12402 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25355540  }} </ref><ref name="pmid26143428">{{cite journal| author=Gangar P, Venkatarajan S| title=Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis. | journal=Dermatol Clin | year= 2015 | volume= 33 | issue= 3 | pages= 489-96 | pmid=26143428 | doi=10.1016/j.det.2015.03.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26143428  }} </ref>
Cutaneous Symptoms<ref name="pmid20672711">{{cite journal| author=Halvani A, Owlia MB, Sami R| title=Lymphomatoid granulomatosis with splenomegaly and pancytopenia. | journal=Zhongguo Fei Ai Za Zhi | year= 2010 | volume= 13 | issue= 1 | pages= 84-6 | pmid=20672711 | doi=10.3779/j.issn.1009-3419.2010.01.17 | pmc=6000673 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20672711  }} </ref><ref name="pmid25355540">{{cite journal| author=Rysgaard CD, Stone MS| title=Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature. | journal=J Cutan Pathol | year= 2015 | volume= 42 | issue= 3 | pages= 188-93 | pmid=25355540 | doi=10.1111/cup.12402 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25355540  }} </ref><ref name="pmid26143428">{{cite journal| author=Gangar P, Venkatarajan S| title=Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis. | journal=Dermatol Clin | year= 2015 | volume= 33 | issue= 3 | pages= 489-96 | pmid=26143428 | doi=10.1016/j.det.2015.03.013 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26143428  }} </ref>
*Erythematous rash
*[[Rash|Erythematous rash]]
*Macules  
*[[Macule|Macules]]
*Papules
*[[Papule|Papules]]
*Plaques  
*[[Plaque|Plaques]]
*Subcutaneous nodules
*[[Nodule (medicine)|Subcutaneous nodules]]
*Larger ulcerated nodules
*[[Nodule (medicine)|Larger ulcerated nodules]]
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 21:12, 18 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kamal Akbar, M.D.[2]

Overview

The most common symptoms of Lymphomatoid granulomatosis include cough, dyspnea, and chest tightness. Patients may present with cutaneous and/or CNS symptoms in some cases.

History and Symptoms

Symptoms of Lymphmatoid granulomatosis include Cough, Dyspnea, and Chest tightness. 

History

Patients with Lymphomatoid granulomatosis may have a positive history of:

Common Symptoms

Common symptoms of [disease] include:

Less Common Symptoms

Less common symptoms of Lymphomatoid granulomatosis include [7][8] [9][10]

CNS Symptoms[11][3][12][10]

Cutaneous Symptoms[10][13][14]

References

  1. ↑ Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L; et al. (2015). "Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations". Am J Surg Pathol. 39 (2): 141–56. doi:10.1097/PAS.0000000000000328. PMC 4293220. PMID 25321327.
  2. ↑ Connors W, Griffiths C, Patel J, Belletrutti PJ (2014). "Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease". BMC Gastroenterol. 14: 127. doi:10.1186/1471-230X-14-127. PMC 4105046. PMID 25022612.
  3. ↑ 3.0 3.1 Kano Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K; et al. (2017). "The Complete Remission of Acquired Immunodeficiency Syndrome-associated Isolated Central Nervous System Lymphomatoid Granulomatosis: A Case Report and Review of the Literature". Intern Med. 56 (18): 2497–2501. doi:10.2169/internalmedicine.8776-16. PMC 5643181. PMID 28824078.
  4. ↑ Xu B, Liu H, Wang B, Zhang H, Wu H, Jin R; et al. (2015). "Fever, Dry Cough and Exertional Dyspnea: Pulmonary Lymphomatoid Granulomatosis Masquerading as Pneumonia, Granulomatosis with Polyangiitis and Infectious Mononucleosis". Intern Med. 54 (23): 3045–9. doi:10.2169/internalmedicine.54.4822. PMID 26631890.
  5. ↑ Ameli F, Ghafourian F, Masir N (2014). "Systematic Epstein-Barr virus-positive T-cell lymphoproliferative disease presenting as a persistent fever and cough: a case report". J Med Case Rep. 8: 288. doi:10.1186/1752-1947-8-288. PMC 4150421. PMID 25163591.
  6. ↑ Olusina D, Ezemba N, Nzegwu MA (2011). "Pulmonary Lymphomatoid Granulomatosis: Report of A Case and Review of Literature". Niger Med J. 52 (1): 60–63. PMC 3180752. PMID 21968985.
  7. ↑ 7.0 7.1 O'Brien S, Schmidt P (2016). "Lymphomatoid Granulomatosis with Paraneoplastic Polymyositis: A Rare Malignancy with Rare Complication". Case Rep Rheumatol. 2016: 8242597. doi:10.1155/2016/8242597. PMC 4757691. PMID 26966605.
  8. ↑ Olmes DG, Agaimy A, Kloska S, Linker RA (2014). "Fatal lymphomatoid granulomatosis with primary CNS-involvement in an immunocompetent 80-year-old woman". BMJ Case Rep. 2014. doi:10.1136/bcr-2014-206825. PMC 4275695. PMID 25535225.
  9. ↑ Costiniuk, Cecilia T.; Karamchandani, Jason; Bessissow, Ali; Routy, Jean-Pierre; Szabo, Jason; Frenette, Charles (2018). "Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report". BMC Infectious Diseases. 18 (1). doi:10.1186/s12879-018-3128-3. ISSN 1471-2334.
  10. ↑ 10.0 10.1 10.2 Halvani A, Owlia MB, Sami R (2010). "Lymphomatoid granulomatosis with splenomegaly and pancytopenia". Zhongguo Fei Ai Za Zhi. 13 (1): 84–6. doi:10.3779/j.issn.1009-3419.2010.01.17. PMC 6000673. PMID 20672711.
  11. ↑ Kim JY, Jung KC, Park SH, Choe JY, Kim JE (2018). "Primary lymphomatoid granulomatosis in the central nervous system: A report of three cases". Neuropathology. doi:10.1111/neup.12467. PMID 29635846.
  12. ↑ Quinones E, Potes LI, Silva N, Lobato-Polo J (2016). "Lymphomatoid granulomatosis of the brain: A case report". Surg Neurol Int. 7 (Suppl 23): S612–6. doi:10.4103/2152-7806.189732. PMC 5025951. PMID 27656321.
  13. ↑ Rysgaard CD, Stone MS (2015). "Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature". J Cutan Pathol. 42 (3): 188–93. doi:10.1111/cup.12402. PMID 25355540.
  14. ↑ Gangar P, Venkatarajan S (2015). "Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis". Dermatol Clin. 33 (3): 489–96. doi:10.1016/j.det.2015.03.013. PMID 26143428.
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