Glucose-6-phosphate dehydrogenase deficiency medical therapy: Difference between revisions
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{{Glucose-6-phosphate dehydrogenase deficiency}} | {{Glucose-6-phosphate dehydrogenase deficiency}} | ||
{{CMG}}; {{AE}}{{MA}} | {{CMG}}; {{AE}}{{MA}} | ||
==Overview== | ==Overview== | ||
The mainstay of treatment for G6PD deficiency is avoidance of the foods such as [[Fava bean|fava beans]] and drugs that cause [[hemolysis]]. Pharmacologic medical therapy is recommended among patients with chronic [[hemolysis]]. [[Blood transfusion]] can be considered in acute phase of [[hemolysis]]. | The mainstay of treatment for G6PD deficiency is avoidance of the foods such as [[Fava bean|fava beans]] and drugs that cause [[hemolysis]]. Pharmacologic medical therapy is recommended among patients with chronic [[hemolysis]]. [[Blood transfusion]] can be considered in the acute phase of [[hemolysis]]. | ||
==Medical Therapy== | ==Medical Therapy== | ||
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** Mild: no treatment | ** Mild: no treatment | ||
** Intermediate: [[phototherapy]] | ** Intermediate: [[phototherapy]] | ||
** | ** Severe: [[exchange transfusions|exchange transfusion]] | ||
* [[Blood transfusion]] in acute phase of [[hemolysis]] | * [[Blood transfusion]] in acute phase of [[hemolysis]] | ||
* [[Dialysis]] in [[Acute kidney injury|acute kidney failure]] | * [[Dialysis]] in [[Acute kidney injury|acute kidney failure]] | ||
* [[Folic Acid|Folic acid]] for patients with chronic [[hemolysis]] | * [[Folic Acid|Folic acid]] for patients with chronic [[hemolysis]]<ref name="pmid27040960">{{cite journal |vauthors=Luzzatto L, Nannelli C, Notaro R |title=Glucose-6-Phosphate Dehydrogenase Deficiency |journal=Hematol. Oncol. Clin. North Am. |volume=30 |issue=2 |pages=373–93 |date=April 2016 |pmid=27040960 |doi=10.1016/j.hoc.2015.11.006 |url=}}</ref> | ||
* | * | ||
* | * | ||
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* '''Adult''' | * '''Adult''' | ||
** [[Folic Acid|Folic acid]]: 1 mg daily | ** [[Folic Acid|Folic acid]]: 1 mg daily | ||
==References== | ==References== | ||
Latest revision as of 23:39, 19 December 2018
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Glucose-6-phosphate dehydrogenase deficiency Microchapters |
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Differentiating Glucose-6-phosphate dehydrogenase deficiency from other Diseases |
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Risk calculators and risk factors for Glucose-6-phosphate dehydrogenase deficiency medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
The mainstay of treatment for G6PD deficiency is avoidance of the foods such as fava beans and drugs that cause hemolysis. Pharmacologic medical therapy is recommended among patients with chronic hemolysis. Blood transfusion can be considered in the acute phase of hemolysis.
Medical Therapy
- The mainstay of treatment for G6PD deficiency is avoidance of the foods such as fava beans and drugs that cause hemolysis.[1]
- Neonatal jaundice:
- Mild: no treatment
- Intermediate: phototherapy
- Severe: exchange transfusion
- Blood transfusion in acute phase of hemolysis
- Dialysis in acute kidney failure
- Folic acid for patients with chronic hemolysis[2]
Disease Name
- Adult
- Folic acid: 1 mg daily