Hemolytic-uremic syndrome other diagnostic studies: Difference between revisions

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__NOTOC__
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{{HUS}}
{{HUS}}
{{CMG}}
{{CMG}} {{shyam}}; {{AE}} {{S.G.}}
 
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==Overview==
==Overview==
Other diagnostic studies associated with HUS include complement protein levels and complement gene mutational analysis.


==Other Diagnostic Studies==
==Other Diagnostic Studies==
:*Kidney [[biopsy]]
Other diagnostic studies associated with HUS include complement protein levels and complement gene mutational analysis.<ref name="pmid21902819">{{cite journal| author=Loirat C, Frémeaux-Bacchi V| title=Atypical hemolytic uremic syndrome. | journal=Orphanet J Rare Dis | year= 2011 | volume= 6 | issue=  | pages= 60 | pmid=21902819 | doi=10.1186/1750-1172-6-60 | pmc=3198674 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21902819  }} </ref>
:*Stool culture may be positive for a certain type of [[E. coli]] bacteria or other bacteria
*Complement factor C3 mutation
 
*Complement factor C4 mutation
==Gallery==
*Complement factor B mutation
 
*Complement factor H mutation
<gallery>
*Complement factor H-related (CFHR) genes 1-3 mutations
Image: Hemolytic syndrome04.jpeg| Escherichia coli in FA stained section of intestine from an 8-month old child suffering from chronic diarrhea. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
*Complement factor I mutation
 
*Membrane cofactor protein (MCP) mutation
Image: Hemolytic syndrome03.jpeg| Scanning electron micrograph (SEM) at 7075X depicts a number of Gram-negative Escherichia coli bacteria of the strain O157:H7, which is one of hundreds of strains of this bacterium. Although most strains are harmless, and live in the intestines of healthy humans and animals, this strain produces a powerful toxin, which can cause severe illness. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
*Thrombomodulin (THBD) mutation
 
*Anti-Complement factor H antibody
Image: Hemolytic syndrome02.jpeg| Colorized scanning electron micrograph (SEM) at 7075X depicts a number of Gram-negative Escherichia coli bacteria of the strain O157:H7. E. coli O157:H7 is one of hundreds of strains of this bacterium. Although most strains are harmless, and live in the intestines of healthy humans and animals, this strain produces a powerful toxin, which can cause severe illness. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
Image: Hemolytic syndrome01.jpeg| Colorized scanning electron micrograph (SEM) at 6836X depicts a number of Gram-negative Escherichia coli bacteria of the strain O157:H7. E. coli O157:H7 is one of hundreds of strains of this bacterium. Although most strains are harmless, and live in the intestines of healthy humans and animals, this strain produces a powerful toxin, which can cause severe illness. <SMALL><SMALL>''[http://phil.cdc.gov/phil/home.asp From Public Health Image Library (PHIL).] ''<ref name=PHIL> {{Cite web | title = Public Health Image Library (PHIL) | url = http://phil.cdc.gov/phil/home.asp}}</ref></SMALL></SMALL>
 
</gallery>


==References==
==References==
{{reflist|2}}
{{Reflist|2}}


{{WH}}
{{WH}}
{{WS}}
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[[Category:Nephrology]]
[[Category:Nephrology]]
[[Category:Hematology]]
[[Category:Hematology]]

Latest revision as of 02:18, 21 December 2018

Hemolytic-uremic syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [3]

Overview

Other diagnostic studies associated with HUS include complement protein levels and complement gene mutational analysis.

Other Diagnostic Studies

Other diagnostic studies associated with HUS include complement protein levels and complement gene mutational analysis.[1]

  • Complement factor C3 mutation
  • Complement factor C4 mutation
  • Complement factor B mutation
  • Complement factor H mutation
  • Complement factor H-related (CFHR) genes 1-3 mutations
  • Complement factor I mutation
  • Membrane cofactor protein (MCP) mutation
  • Thrombomodulin (THBD) mutation
  • Anti-Complement factor H antibody

References

  1. ↑ Loirat C, Frémeaux-Bacchi V (2011). "Atypical hemolytic uremic syndrome". Orphanet J Rare Dis. 6: 60. doi:10.1186/1750-1172-6-60. PMC 3198674. PMID 21902819.

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