Hemochromatosis surgery: Difference between revisions
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{{Hemochromatosis}} | {{Hemochromatosis}} | ||
{{CMG}}; {{AE}} | {{CMG}} {{shyam}}; {{AE}}{{SKA}} | ||
==Overview== | ==Overview== | ||
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Early diagnosis is important because the late effects of iron accumulation can be wholly prevented by periodic [[Venipuncture|phlebotomies]] (by venesection) comparable in volume to [[blood donation]]s.<ref>[http://www.mayoclinic.com/health/hemochromatosis/DS00455/DSECTION=7 Hemochromatosis - Treatment]</ref> Treatment is initiated when [[ferritin]] levels reach 300 micrograms per litre (or 200 in nonpregnant [[premenopausal]] women).<ref name="pmid19264677">{{cite journal| author=Hankins JS, McCarville MB, Loeffler RB, Smeltzer MP, Onciu M, Hoffer FA et al.| title=R2* magnetic resonance imaging of the liver in patients with iron overload. | journal=Blood | year= 2009 | volume= 113 | issue= 20 | pages= 4853-5 | pmid=19264677 | doi=10.1182/blood-2008-12-191643 | pmc=2686136 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19264677 }}</ref> | Early diagnosis is important because the late effects of iron accumulation can be wholly prevented by periodic [[Venipuncture|phlebotomies]] (by venesection) comparable in volume to [[blood donation]]s.<ref>[http://www.mayoclinic.com/health/hemochromatosis/DS00455/DSECTION=7 Hemochromatosis - Treatment]</ref> Treatment is initiated when [[ferritin]] levels reach 300 micrograms per litre (or 200 in nonpregnant [[premenopausal]] women).<ref name="pmid19264677">{{cite journal| author=Hankins JS, McCarville MB, Loeffler RB, Smeltzer MP, Onciu M, Hoffer FA et al.| title=R2* magnetic resonance imaging of the liver in patients with iron overload. | journal=Blood | year= 2009 | volume= 113 | issue= 20 | pages= 4853-5 | pmid=19264677 | doi=10.1182/blood-2008-12-191643 | pmc=2686136 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19264677 }}</ref> | ||
Every bag of blood | Every bag of blood contains 200-250 milligrams of iron. Phlebotomy (or [[bloodletting]]) is usually done at a weekly interval until [[ferritin]] levels are less than 50 nanograms per millilitre. After that, 1-4 donations per year are usually needed to maintain iron balance. | ||
==References== | ==References== | ||
Latest revision as of 18:34, 1 January 2019
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Hemochromatosis Microchapters |
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Treatment |
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Hemochromatosis surgery On the Web |
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American Roentgen Ray Society Images of Hemochromatosis surgery |
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Risk calculators and risk factors for Hemochromatosis surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Sunny Kumar MD [3]
Overview
Surgery does not play role in treatment however liver biopsy is obtained in case of evaluations of diagnosis of few cases of iron over load conditions.
Surgery
Early diagnosis is important because the late effects of iron accumulation can be wholly prevented by periodic phlebotomies (by venesection) comparable in volume to blood donations.[1] Treatment is initiated when ferritin levels reach 300 micrograms per litre (or 200 in nonpregnant premenopausal women).[2]
Every bag of blood contains 200-250 milligrams of iron. Phlebotomy (or bloodletting) is usually done at a weekly interval until ferritin levels are less than 50 nanograms per millilitre. After that, 1-4 donations per year are usually needed to maintain iron balance.
References
- ↑ Hemochromatosis - Treatment
- ↑ Hankins JS, McCarville MB, Loeffler RB, Smeltzer MP, Onciu M, Hoffer FA; et al. (2009). "R2* magnetic resonance imaging of the liver in patients with iron overload". Blood. 113 (20): 4853–5. doi:10.1182/blood-2008-12-191643. PMC 2686136. PMID 19264677.