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{{Infobox_gene}}
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'''Splicing factor 3 subunit 1''' is a [[protein]] that in humans is encoded by the ''SF3A1'' [[gene]].<ref name="pmid7489498">{{cite journal |author1=Kramer A |author2=Mulhauser F |author3=Wersig C |author4=Groning K |author5=Bilbe G | title = Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae | journal = RNA | volume = 1 | issue = 3 | pages = 260–72 |date=January 1996 | pmid = 7489498 | pmc = 1369079 | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SF3A1 splicing factor 3a, subunit 1, 120kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10291| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_SF3A1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1we7.
| PDB = {{PDB2|1we7}}, {{PDB2|1zkh}}, {{PDB2|2dt6}}, {{PDB2|2dt7}}
| Name = Splicing factor 3a, subunit 1, 120kDa
| HGNCid = 10765
| Symbol = SF3A1
| AltSymbols =; PRP21; PRPF21; SAP114; SF3A120
| OMIM = 605595
| ECnumber =
| Homologene = 4294
| MGIid = 1914715
| GeneAtlas_image1 = PBB_GE_SF3A1_201356_at_tn.png
| GeneAtlas_image2 = PBB_GE_SF3A1_201357_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_SF3A1_216457_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005681 |text = spliceosome}}
| Process = {{GNF_GO|id=GO:0000389 |text = nuclear mRNA 3'-splice site recognition}} {{GNF_GO|id=GO:0000398 |text = nuclear mRNA splicing, via spliceosome}} {{GNF_GO|id=GO:0006464 |text = protein modification process}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10291
    | Hs_Ensembl = ENSG00000099995
    | Hs_RefseqProtein = NP_001005409
    | Hs_RefseqmRNA = NM_001005409
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 22
    | Hs_GenLoc_start = 29057979
    | Hs_GenLoc_end = 29082913
    | Hs_Uniprot = Q15459
    | Mm_EntrezGene = 67465
    | Mm_Ensembl = ENSMUSG00000002129
    | Mm_RefseqmRNA = NM_026175
    | Mm_RefseqProtein = NP_080451
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 4060371
    | Mm_GenLoc_end = 4080632
    | Mm_Uniprot = Q3TVM1
  }}
}}
'''Splicing factor 3a, subunit 1, 120kDa''', also known as '''SF3A1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SF3A1 splicing factor 3a, subunit 1, 120kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10291| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =
| summary_text = This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.<ref name="entrez">{{cite web | title = Entrez Gene: SF3A1 splicing factor 3a, subunit 1, 120kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10291| accessdate = }}</ref>
| summary_text = This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.<ref name="entrez"/>
}}
}}
==Interactions==
SF3A1 has been shown to [[Protein-protein interaction|interact]] with [[SF3A3]]<ref name=pmid11533230>{{cite journal |last=Nesic |first=D |authorlink= |author2=Krämer A  |date=October 2001 |title=Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation |journal=Mol. Cell. Biol. |volume=21 |issue=19 |pages=6406–17 |publisher= |location = United States| issn = 0270-7306| pmid = 11533230 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.21.19.6406-6417.2001 |pmc=99788 }}</ref><ref name=pmid8022796>{{cite journal |last=Chiara |first=M D |authorlink= |author2=Champion-Arnaud P |author3=Buvoli M |author4=Nadal-Ginard B |author5=Reed R  |date=July 1994 |title=Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114 |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=91 |issue=14 |pages=6403–7 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8022796 | bibcode =1994PNAS...91.6403C | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1073/pnas.91.14.6403 |pmc=44210 }}</ref> and [[CDC5L]].<ref name=pmid11101529>{{cite journal |last=Ajuh |first=P |authorlink= |author2=Kuster B |author3=Panov K |author4=Zomerdijk J C |author5=Mann M |author6=Lamond A I  |date=Dec 2000 |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry |journal=EMBO J. |volume=19 |issue=23 |pages=6569–81 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 11101529 |doi = 10.1093/emboj/19.23.6569 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=305846 }}</ref>


==References==
==References==
{{reflist|2}}
{{Reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{Refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading
| citations =  
| citations =
*{{cite journal | author=Krämer A, Mulhauser F, Wersig C, ''et al.'' |title=Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae. |journal=RNA |volume=1 |issue= 3 |pages= 260-72 |year= 1996 |pmid= 7489498 |doi= }}
*{{cite journal   |vauthors=Chiara MD, Champion-Arnaud P, Buvoli M, etal |title=Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 14 |pages= 6403–7 |year= 1994 |pmid= 8022796 |doi=10.1073/pnas.91.14.6403  | pmc=44210  |bibcode=1994PNAS...91.6403C }}
*{{cite journal  | author=Chiara MD, Champion-Arnaud P, Buvoli M, ''et al.'' |title=Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 14 |pages= 6403-7 |year= 1994 |pmid= 8022796 |doi=  }}
*{{cite journal  |author1=Rain JC |author2=Tartakoff AM |author3=Krämer A |author4=Legrain P |title=Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution. |journal=RNA |volume=2 |issue= 6 |pages= 535–50 |year= 1996 |pmid= 8718683 |doi=  | pmc=1369393  }}
*{{cite journal | author=Rain JC, Tartakoff AM, Krämer A, Legrain P |title=Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution. |journal=RNA |volume=2 |issue= 6 |pages= 535-50 |year= 1996 |pmid= 8718683 |doi= }}
*{{cite journal   |vauthors=Neubauer G, King A, Rappsilber J, etal |title=Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. |journal=Nat. Genet. |volume=20 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9731529 |doi= 10.1038/1700 }}
*{{cite journal  | author=Neubauer G, King A, Rappsilber J, ''et al.'' |title=Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. |journal=Nat. Genet. |volume=20 |issue= 1 |pages= 46-50 |year= 1998 |pmid= 9731529 |doi= 10.1038/1700 }}
*{{cite journal  |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi= 10.1101/gr.8.11.1097}}
*{{cite journal  | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097-108 |year= 1999 |pmid= 9847074 |doi= }}
*{{cite journal  |author1=Krämer A |author2=Grüter P |author3=Gröning K |author4=Kastner B |title=Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP. |journal=J. Cell Biol. |volume=145 |issue= 7 |pages= 1355–68 |year= 1999 |pmid= 10385517 |doi=10.1083/jcb.145.7.1355  | pmc=2133165  }}
*{{cite journal | author=Krämer A, Grüter P, Gröning K, Kastner B |title=Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP. |journal=J. Cell Biol. |volume=145 |issue= 7 |pages= 1355-68 |year= 1999 |pmid= 10385517 |doi= }}
*{{cite journal   |vauthors=Dunham I, Shimizu N, Roe BA, etal |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 |bibcode=1999Natur.402..489D }}
*{{cite journal  | author=Dunham I, Shimizu N, Roe BA, ''et al.'' |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489-95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031 }}
*{{cite journal  |author1=Das R |author2=Zhou Z |author3=Reed R |title=Functional association of U2 snRNP with the ATP-independent spliceosomal complex E. |journal=Mol. Cell |volume=5 |issue= 5 |pages= 779–87 |year= 2000 |pmid= 10882114 |doi=10.1016/S1097-2765(00)80318-4  }}
*{{cite journal  | author=Das R, Zhou Z, Reed R |title=Functional association of U2 snRNP with the ATP-independent spliceosomal complex E. |journal=Mol. Cell |volume=5 |issue= 5 |pages= 779-87 |year= 2000 |pmid= 10882114 |doi=  }}
*{{cite journal  |author1=Gunther M |author2=Laithier M |author3=Brison O |title=A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. |journal=Mol. Cell. Biochem. |volume=210 |issue= 1–2 |pages= 131–42 |year= 2000 |pmid= 10976766 |doi=10.1023/A:1007177623283 }}
*{{cite journal | author=Gunther M, Laithier M, Brison O |title=A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. |journal=Mol. Cell. Biochem. |volume=210 |issue= 1-2 |pages= 131-42 |year= 2000 |pmid= 10976766 |doi=  }}
*{{cite journal   |vauthors=Ajuh P, Kuster B, Panov K, etal |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6569–81 |year= 2001 |pmid= 11101529 |doi= 10.1093/emboj/19.23.6569 | pmc=305846 }}
*{{cite journal | author=Ajuh P, Kuster B, Panov K, ''et al.'' |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6569-81 |year= 2001 |pmid= 11101529 |doi= 10.1093/emboj/19.23.6569 }}
*{{cite journal   |vauthors=Suzuki Y, Tsunoda T, Sese J, etal |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes. |journal=Genome Res. |volume=11 |issue= 5 |pages= 677–84 |year= 2001 |pmid= 11337467 |doi=   10.1101/gr.gr-1640r| pmc=311086 }}
*{{cite journal | author=Suzuki Y, Tsunoda T, Sese J, ''et al.'' |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes. |journal=Genome Res. |volume=11 |issue= 5 |pages= 677-84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.164001 }}
*{{cite journal   |vauthors=Will CL, Schneider C, MacMillan AM, etal |title=A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. |journal=EMBO J. |volume=20 |issue= 16 |pages= 4536–46 |year= 2001 |pmid= 11500380 |doi= 10.1093/emboj/20.16.4536  | pmc=125580 }}
*{{cite journal  | author=Will CL, Schneider C, MacMillan AM, ''et al.'' |title=A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. |journal=EMBO J. |volume=20 |issue= 16 |pages= 4536-46 |year= 2001 |pmid= 11500380 |doi= 10.1093/emboj/20.16.4536 }}
*{{cite journal  |author1=Nesic D |author2=Krämer A |title=Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation. |journal=Mol. Cell. Biol. |volume=21 |issue= 19 |pages= 6406–17 |year= 2001 |pmid= 11533230 |doi=10.1128/MCB.21.19.6406-6417.2001  | pmc=99788  }}
*{{cite journal | author=Nesic D, Krämer A |title=Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation. |journal=Mol. Cell. Biol. |volume=21 |issue= 19 |pages= 6406-17 |year= 2001 |pmid= 11533230 |doi=  }}
*{{cite journal   |vauthors=Jurica MS, Licklider LJ, Gygi SR, etal |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=10.1017/S1355838202021088 | pmc=1370266  }}
*{{cite journal | author=Jurica MS, Licklider LJ, Gygi SR, ''et al.'' |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426-39 |year= 2002 |pmid= 11991638 |doi=  }}
*{{cite journal   |vauthors=Will CL, Urlaub H, Achsel T, etal |title=Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. |journal=EMBO J. |volume=21 |issue= 18 |pages= 4978–88 |year= 2002 |pmid= 12234937 |doi=10.1093/emboj/cdf480  | pmc=126279 }}
*{{cite journal | author=Will CL, Urlaub H, Achsel T, ''et al.'' |title=Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. |journal=EMBO J. |volume=21 |issue= 18 |pages= 4978-88 |year= 2002 |pmid= 12234937 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 |bibcode=2004PNAS..10112130B }}
*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal  |author1=Nesic D |author2=Tanackovic G |author3=Krämer A |title=A role for Cajal bodies in the final steps of U2 snRNP biogenesis. |journal=J. Cell Sci. |volume=117 |issue= Pt 19 |pages= 4423–33 |year= 2005 |pmid= 15316075 |doi= 10.1242/jcs.01308 |url=https://archive-ouverte.unige.ch/unige:17542/ATTACHMENT01 }}
*{{cite journal  | author=Nesic D, Tanackovic G, Krämer A |title=A role for Cajal bodies in the final steps of U2 snRNP biogenesis. |journal=J. Cell. Sci. |volume=117 |issue= Pt 19 |pages= 4423-33 |year= 2005 |pmid= 15316075 |doi= 10.1242/jcs.01308 }}
*{{cite journal  |author1=Lin KT |author2=Lu RM |author3=Tarn WY |title=The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. |journal=Mol. Cell. Biol. |volume=24 |issue= 20 |pages= 9176–85 |year= 2004 |pmid= 15456888 |doi= 10.1128/MCB.24.20.9176-9185.2004  | pmc=517884 }}
*{{cite journal | author=Lin KT, Lu RM, Tarn WY |title=The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. |journal=Mol. Cell. Biol. |volume=24 |issue= 20 |pages= 9176-85 |year= 2004 |pmid= 15456888 |doi= 10.1128/MCB.24.20.9176-9185.2004 }}
*{{cite journal   |vauthors=Collins JE, Wright CL, Edwards CA, etal |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84  | pmc=545604 }}
*{{cite journal  | author=Collins JE, Wright CL, Edwards CA, ''et al.'' |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84 }}
}}
{{Refend}}
 
==External links==
* {{UCSC genome browser|SF3A1}}
* {{UCSC gene details|SF3A1}}
 
{{PDB Gallery|geneid=10291}}
 
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{{refend}}


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Latest revision as of 12:23, 9 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Splicing factor 3 subunit 1 is a protein that in humans is encoded by the SF3A1 gene.[1][2]

This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms.[2]

Interactions

SF3A1 has been shown to interact with SF3A3[3][4] and CDC5L.[5]

References

  1. ↑ Kramer A; Mulhauser F; Wersig C; Groning K; Bilbe G (January 1996). "Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae". RNA. 1 (3): 260–72. PMC 1369079. PMID 7489498.
  2. ↑ 2.0 2.1 "Entrez Gene: SF3A1 splicing factor 3a, subunit 1, 120kDa".
  3. ↑ Nesic, D; Krämer A (October 2001). "Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation". Mol. Cell. Biol. United States. 21 (19): 6406–17. doi:10.1128/MCB.21.19.6406-6417.2001. ISSN 0270-7306. PMC 99788. PMID 11533230.
  4. ↑ Chiara, M D; Champion-Arnaud P; Buvoli M; Nadal-Ginard B; Reed R (July 1994). "Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114". Proc. Natl. Acad. Sci. U.S.A. UNITED STATES. 91 (14): 6403–7. Bibcode:1994PNAS...91.6403C. doi:10.1073/pnas.91.14.6403. ISSN 0027-8424. PMC 44210. PMID 8022796.
  5. ↑ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (Dec 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. ENGLAND. 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529.

Further reading

External links



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