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{{ | '''AP-3 complex subunit sigma-2''' is a [[protein]] that in humans is encoded by the ''AP3S2'' [[gene]].<ref name="pmid9118953">{{cite journal |vauthors=Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS | title = AP-3: an adaptor-like protein complex with ubiquitous expression | journal = EMBO J | volume = 16 | issue = 5 | pages = 917–28 |date=Apr 1997 | pmid = 9118953 | pmc = 1169692 | doi = 10.1093/emboj/16.5.917 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10239| accessdate = }}</ref> | ||
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==Interactions== | |||
AP3S2 has been shown to [[Protein-protein interaction|interact]] with [[AP3B1]].<ref name=pmid9182526>{{cite journal |last=Dell'Angelica |first=E C |authorlink= |author2=Ooi C E |author3=Bonifacino J S |date=Jun 1997 |title=Beta3A-adaptin, a subunit of the adaptor-like complex AP-3 |journal=J. Biol. Chem. |volume=272 |issue=24 |pages=15078–84 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9182526 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.272.24.15078 }}</ref> | |||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | | *{{cite journal |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }} | ||
*{{cite journal |vauthors=Dell'Angelica EC, Ooi CE, Bonifacino JS |title=Beta3A-adaptin, a subunit of the adaptor-like complex AP-3 |journal=J. Biol. Chem. |volume=272 |issue= 24 |pages= 15078–84 |year= 1997 |pmid= 9182526 |doi=10.1074/jbc.272.24.15078 }} | |||
*{{cite journal | | *{{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Rous BA, Reaves BJ, Ihrke G |title=Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes |journal=Mol. Biol. Cell |volume=13 |issue= 3 |pages= 1071–82 |year= 2002 |pmid= 11907283 |doi= 10.1091/mbc.01-08-0409 | pmc=99620 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC |title=BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 28191–9 |year= 2002 |pmid= 12019270 |doi= 10.1074/jbc.M204011200 }} | ||
*{{cite journal | | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }} | ||
*{{cite journal | | *{{cite journal |vauthors=Nie Z, Boehm M, Boja ES |title=Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1 |journal=Dev. Cell |volume=5 |issue= 3 |pages= 513–21 |year= 2003 |pmid= 12967569 |doi=10.1016/S1534-5807(03)00234-X |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Salazar G, Love R, Werner E |title=The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation |journal=Mol. Biol. Cell |volume=15 |issue= 2 |pages= 575–87 |year= 2004 |pmid= 14657250 |doi= 10.1091/mbc.E03-06-0401 | pmc=329249 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Lefrançois S, Janvier K, Boehm M |title=An ear-core interaction regulates the recruitment of the AP-3 complex to membranes |journal=Dev. Cell |volume=7 |issue= 4 |pages= 619–25 |year= 2004 |pmid= 15469849 |doi= 10.1016/j.devcel.2004.08.009 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}} | ||
*{{cite journal | | *{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal|bibcode=2005Natur.437.1173R }} | ||
*{{cite journal | | |||
}} | }} | ||
{{refend}} | {{refend}} | ||
==External links== | |||
* {{UCSC genome browser|AP3S2}} | |||
* {{UCSC gene details|AP3S2}} | |||
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
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Ensembl |
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RefSeq (mRNA) |
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AP-3 complex subunit sigma-2 is a protein that in humans is encoded by the AP3S2 gene.[1][2]
Interactions
AP3S2 has been shown to interact with AP3B1.[3]
References
- ↑ Dell'Angelica EC, Ohno H, Ooi CE, Rabinovich E, Roche KW, Bonifacino JS (Apr 1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
- ↑ "Entrez Gene: AP3S2 adaptor-related protein complex 3, sigma 2 subunit".
- ↑ Dell'Angelica, E C; Ooi C E; Bonifacino J S (Jun 1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. UNITED STATES. 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. ISSN 0021-9258. PMID 9182526.
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Dell'Angelica EC, Ooi CE, Bonifacino JS (1997). "Beta3A-adaptin, a subunit of the adaptor-like complex AP-3". J. Biol. Chem. 272 (24): 15078–84. doi:10.1074/jbc.272.24.15078. PMID 9182526.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Rous BA, Reaves BJ, Ihrke G, et al. (2002). "Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes". Mol. Biol. Cell. 13 (3): 1071–82. doi:10.1091/mbc.01-08-0409. PMC 99620. PMID 11907283.
- Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC (2002). "BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules". J. Biol. Chem. 277 (31): 28191–9. doi:10.1074/jbc.M204011200. PMID 12019270.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Nie Z, Boehm M, Boja ES, et al. (2003). "Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1". Dev. Cell. 5 (3): 513–21. doi:10.1016/S1534-5807(03)00234-X. PMID 12967569.
- Salazar G, Love R, Werner E, et al. (2004). "The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation". Mol. Biol. Cell. 15 (2): 575–87. doi:10.1091/mbc.E03-06-0401. PMC 329249. PMID 14657250.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Lefrançois S, Janvier K, Boehm M, et al. (2004). "An ear-core interaction regulates the recruitment of the AP-3 complex to membranes". Dev. Cell. 7 (4): 619–25. doi:10.1016/j.devcel.2004.08.009. PMID 15469849.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
External links
- AP3S2 human gene location in the UCSC Genome Browser.
- AP3S2 human gene details in the UCSC Genome Browser.
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