RAB8B: Difference between revisions

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Latest revision as of 12:46, 9 January 2019

Ras-related protein Rab-8B is a protein that in humans is encoded by the RAB8B gene.^[1]^[2]^[3]

References

↑ Chen D, Guo J, Gahl WA (Mar 1997). "RAB GTPases expressed in human melanoma cells". Biochim Biophys Acta. 1355 (1): 1–6. doi:10.1016/S0167-4889(96)00169-3. PMID 9030196.
↑ Heidrych P, Zimmermann U, Bress A, Pusch CM, Ruth P, Pfister M, Knipper M, Blin N (Nov 2008). "Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form". Hum Mol Genet. 17 (23): 3814–21. doi:10.1093/hmg/ddn279. PMID 18772196.
↑ "Entrez Gene: RAB8B RAB8B, member RAS oncogene family".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Lau AS, Mruk DD (2003). "Rab8B GTPase and junction dynamics in the testis". Endocrinology. 144 (4): 1549–63. doi:10.1210/en.2002-220893. PMID 12639940.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hattula K, Furuhjelm J, Arffman A, Peränen J (2003). "A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport". Mol. Biol. Cell. 13 (9): 3268–80. doi:10.1091/mbc.E02-03-0143. PMC 124888. PMID 12221131.
de Bruyn KM, de Rooij J, Wolthuis RM, et al. (2000). "RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral". J. Biol. Chem. 275 (38): 29761–6. doi:10.1074/jbc.M001160200. PMID 10889189.
Armstrong J, Thompson N, Squire JH, et al. (1997). "Identification of a novel member of the Rab8 family from the rat basophilic leukaemia cell line, RBL.2H3". J. Cell Sci. 109 (6): 1265–74. PMID 8799816.

This article on a gene on human chromosome 15 is a stub. You can help Wikipedia by expanding it.

[pmid9030196-1] Chen D, Guo J, Gahl WA (Mar 1997). "RAB GTPases expressed in human melanoma cells". Biochim Biophys Acta. 1355 (1): 1–6. doi:10.1016/S0167-4889(96)00169-3. PMID 9030196.

[pmid18772196-2] Heidrych P, Zimmermann U, Bress A, Pusch CM, Ruth P, Pfister M, Knipper M, Blin N (Nov 2008). "Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form". Hum Mol Genet. 17 (23): 3814–21. doi:10.1093/hmg/ddn279. PMID 18772196.

[entrez-3] "Entrez Gene: RAB8B RAB8B, member RAS oncogene family".

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[2]

[3]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Ras-related protein Rab-8B''' is a [[protein]] that in humans is encoded by the ''RAB8B'' [[gene]].<ref name="pmid9030196">{{cite journal | vauthors = Chen D, Guo J, Gahl WA | title = RAB GTPases expressed in human melanoma cells | journal = Biochim Biophys Acta | volume = 1355 | issue = 1 | pages = 1–6 |date=Mar 1997 | pmid = 9030196 | pmc =  | doi =10.1016/S0167-4889(96)00169-3  }}</ref><ref name="pmid18772196">{{cite journal | vauthors = Heidrych P, Zimmermann U, Bress A, Pusch CM, Ruth P, Pfister M, Knipper M, Blin N | title = Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form | journal = Hum Mol Genet | volume = 17 | issue = 23 | pages = 3814–21 |date=Nov 2008 | pmid = 18772196 | pmc =  | doi = 10.1093/hmg/ddn279 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB8B RAB8B, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51762| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = RAB8B, member RAS oncogene family
- | HGNCid = 30273
- | Symbol = RAB8B
- | AltSymbols =; FLJ38125
- | OMIM =
- | ECnumber =
- | Homologene = 69220
- | MGIid = 2442982
-  | GeneAtlas_image1 = PBB_GE_RAB8B_219210_s_at_tn.png
-  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}}{{GNF_GO|id=GO:0003924 |text = GTPase activity}}{{GNF_GO|id=GO:0005524 |text = ATP binding}}{{GNF_GO|id=GO:0005525 |text = GTP binding}}{{GNF_GO|id=GO:0008134 |text = transcription factor binding}}
- | Component = {{GNF_GO|id=GO:0005575 |text = cellular_component}} {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0016020 |text = membrane}}
- | Process = {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 51762
-    | Hs_Ensembl = ENSG00000166128
-    | Hs_RefseqProtein = NP_057614
-    | Hs_RefseqmRNA = NM_016530
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 15
-    | Hs_GenLoc_start = 61268781
-    | Hs_GenLoc_end = 61347028
-    | Hs_Uniprot = Q92930
-    | Mm_EntrezGene = 235442
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA = NM_173413
-    | Mm_RefseqProtein = NP_775589
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''RAB8B, member RAS oncogene family''', also known as '''RAB8B''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB8B RAB8B, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51762| accessdate = }}</ref>
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 {{PBB_Summary
@@ Line 55: / Line 8: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Lau AS, Mruk DD |title=Rab8B GTPase and junction dynamics in the testis. |journal=Endocrinology |volume=144 |issue= 4 |pages= 1549-63 |year= 2003 |pmid= 12639940 |doi=  }}
+*{{cite journal  | vauthors=Lau AS, Mruk DD |title=Rab8B GTPase and junction dynamics in the testis. |journal=Endocrinology |volume=144 |issue= 4 |pages= 1549–63 |year= 2003 |pmid= 12639940 |doi=10.1210/en.2002-220893  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Hattula K, Furuhjelm J, Arffman A, Peränen J |title=A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport. |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3268-80 |year= 2003 |pmid= 12221131 |doi= 10.1091/mbc.E02-03-0143 }}
+*{{cite journal  | vauthors=Hattula K, Furuhjelm J, Arffman A, Peränen J |title=A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport. |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3268–80 |year= 2003 |pmid= 12221131 |doi= 10.1091/mbc.E02-03-0143  | pmc=124888 }}
-*{{cite journal  | author=de Bruyn KM, de Rooij J, Wolthuis RM, ''et al.'' |title=RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29761-6 |year= 2000 |pmid= 10889189 |doi= 10.1074/jbc.M001160200 }}
+*{{cite journal   |vauthors=de Bruyn KM, de Rooij J, Wolthuis RM, etal |title=RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29761–6 |year= 2000 |pmid= 10889189 |doi= 10.1074/jbc.M001160200 }}
-*{{cite journal  | author=Chen D, Guo J, Gahl WA |title=RAB GTPases expressed in human melanoma cells. |journal=Biochim. Biophys. Acta |volume=1355 |issue= 1 |pages= 1-6 |year= 1997 |pmid= 9030196 |doi=  }}
+*{{cite journal   |vauthors=Armstrong J, Thompson N, Squire JH, etal |title=Identification of a novel member of the Rab8 family from the rat basophilic leukaemia cell line, RBL.2H3. |journal=J. Cell Sci. |volume=109 |issue=  6|pages= 1265–74 |year= 1997 |pmid= 8799816 |doi=  }}
-*{{cite journal  | author=Armstrong J, Thompson N, Squire JH, ''et al.'' |title=Identification of a novel member of the Rab8 family from the rat basophilic leukaemia cell line, RBL.2H3. |journal=J. Cell. Sci. |volume=109 ( Pt 6) |issue=  |pages= 1265-74 |year= 1997 |pmid= 8799816 |doi=  }}
 }}
 {{refend}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
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+| update_citations = yes
+}}
 {{gene-15-stub}}
-{{WikiDoc Sources}}

RAB8B: Difference between revisions

Latest revision as of 12:46, 9 January 2019

References

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