TOPORS: Difference between revisions

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Latest revision as of 07:32, 10 January 2019

E3 ubiquitin-protein ligase Topors is an enzyme that in humans is encoded by the TOPORS gene.^[1]^[2]^[3]^[4]

References

↑ Haluska P Jr, Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH (Jul 1999). "Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein". Nucleic Acids Res. 27 (12): 2538–44. doi:10.1093/nar/27.12.2538. PMC 148458. PMID 10352183.
↑ Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH (Jun 2002). "The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies". Exp Cell Res. 277 (2): 152–60. doi:10.1006/excr.2002.5550. PMID 12083797.
↑ Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, Munro PM, Gal A, Hamel CP, Marigo V, Ponting CP, Wissinger B, Zrenner E, Matter K, Swaroop A, Koenekoop RK, Bhattacharya SS (Oct 2007). "Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy". Am J Hum Genet. 81 (5): 1098–103. doi:10.1086/521953. PMC 2265653. PMID 17924349.
↑ "Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich".

Zhou R, Wen H, Ao SZ (1999). "Identification of a novel gene encoding a p53-associated protein". Gene. 235 (1–2): 93–101. doi:10.1016/S0378-1119(99)00203-6. PMID 10415337.
Souto-Carneiro MM, Krenn V, Hermann R, et al. (2001). "IgVH genes from different anatomical regions, with different histopathological patterns, of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process". Arthritis Res. 2 (4): 303–14. doi:10.1186/ar105. PMC 17813. PMID 11056671.
Chu D, Kakazu N, Gorrin-Rivas MJ, et al. (2001). "Cloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequence". J. Biol. Chem. 276 (17): 14004–13. doi:10.1074/jbc.M010262200. PMID 11278651.
Weger S, Hammer E, Heilbronn R (2002). "Topors, a p53 and topoisomerase I binding protein, interacts with the adeno-associated virus (AAV-2) Rep78/68 proteins and enhances AAV-2 gene expression". J. Gen. Virol. 83 (Pt 3): 511–6. doi:10.1099/0022-1317-83-3-511. PMID 11842245.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Imabayashi H, Mori T, Gojo S, et al. (2003). "Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis". Exp. Cell Res. 288 (1): 35–50. doi:10.1016/S0014-4827(03)00130-7. PMID 12878157.
Weger S, Hammer E, Engstler M (2003). "The DNA topoisomerase I binding protein topors as a novel cellular target for SUMO-1 modification: characterization of domains necessary for subcellular localization and sumolation". Exp. Cell Res. 290 (1): 13–27. doi:10.1016/S0014-4827(03)00292-1. PMID 14516784.
Saleem A, Dutta J, Malegaonkar D, et al. (2004). "The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor". Oncogene. 23 (31): 5293–300. doi:10.1038/sj.onc.1207700. PMID 15107820.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Rajendra R, Malegaonkar D, Pungaliya P, et al. (2004). "Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53". J. Biol. Chem. 279 (35): 36440–4. doi:10.1074/jbc.C400300200. PMID 15247280.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Oyanagi H, Takenaka K, Ishikawa S, et al. (2005). "Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer". Lung Cancer. 46 (1): 21–8. doi:10.1016/j.lungcan.2004.03.009. PMID 15364129.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Flatten K, Dai NT, Vroman BT, et al. (2005). "The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons". J. Biol. Chem. 280 (14): 14349–55. doi:10.1074/jbc.M411890200. PMID 15699047.
Lin L, Ozaki T, Takada Y, et al. (2005). "topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage". Oncogene. 24 (21): 3385–96. doi:10.1038/sj.onc.1208554. PMID 15735665.
Weger S, Hammer E, Heilbronn R (2005). "Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo". FEBS Lett. 579 (22): 5007–12. doi:10.1016/j.febslet.2005.07.088. PMID 16122737.
Papaioannou M, Chakarova CF, Prescott DC, et al. (2006). "A new locus (RP31) for autosomal dominant retinitis pigmentosa maps to chromosome 9p". Hum. Genet. 118 (3–4): 501–3. doi:10.1007/s00439-005-0063-3. PMID 16189705.

External links

TOPORS human gene location in the UCSC Genome Browser.
TOPORS human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

[pmid10352183-1] Haluska P Jr, Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH (Jul 1999). "Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein". Nucleic Acids Res. 27 (12): 2538–44. doi:10.1093/nar/27.12.2538. PMC 148458. PMID 10352183.

[pmid12083797-2] Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH (Jun 2002). "The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies". Exp Cell Res. 277 (2): 152–60. doi:10.1006/excr.2002.5550. PMID 12083797.

[pmid17924349-3] Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, Munro PM, Gal A, Hamel CP, Marigo V, Ponting CP, Wissinger B, Zrenner E, Matter K, Swaroop A, Koenekoop RK, Bhattacharya SS (Oct 2007). "Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy". Am J Hum Genet. 81 (5): 1098–103. doi:10.1086/521953. PMC 2265653. PMID 17924349.

[entrez-4] "Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich".

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Underlinked|date=June 2016}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''E3 ubiquitin-protein ligase Topors''' is an [[enzyme]] that in humans is encoded by the ''TOPORS'' [[gene]].<ref name="pmid10352183">{{cite journal | vauthors = ((Haluska P Jr)), Saleem A, Rasheed Z, Ahmed F, Su EW, Liu LF, Rubin EH | title = Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein | journal = Nucleic Acids Res | volume = 27 | issue = 12 | pages = 2538–44 |date=Jul 1999 | pmid = 10352183 | pmc = 148458 | doi =10.1093/nar/27.12.2538  }}</ref><ref name="pmid12083797">{{cite journal | vauthors = Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH | title = The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies | journal = Exp Cell Res | volume = 277 | issue = 2 | pages = 152–60 |date=Jun 2002 | pmid = 12083797 | pmc =  | doi =10.1006/excr.2002.5550  }}</ref><ref name="pmid17924349">{{cite journal | vauthors = Chakarova CF, Papaioannou MG, Khanna H, Lopez I, Waseem N, Shah A, Theis T, Friedman J, Maubaret C, Bujakowska K, Veraitch B, Abd El-Aziz MM, Prescott de Q, Parapuram SK, Bickmore WA, Munro PM, Gal A, Hamel CP, Marigo V, Ponting CP, Wissinger B, Zrenner E, Matter K, Swaroop A, Koenekoop RK, Bhattacharya SS | title = Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy | journal = Am J Hum Genet | volume = 81 | issue = 5 | pages = 1098–103 |date=Oct 2007 | pmid = 17924349 | pmc = 2265653 | doi = 10.1086/521953 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10210| accessdate = }}</ref>
-| require_manual_inspection = no
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Topoisomerase I binding, arginine/serine-rich
- | HGNCid = 21653
- | Symbol = TOPORS
- | AltSymbols =; LUN; TP53BPL
- | OMIM = 609507
- | ECnumber =
- | Homologene = 4237
- | MGIid = 2146189
- | GeneAtlas_image1 = PBB_GE_TOPORS_204071_s_at_tn.png
-  | Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003823 |text = antigen binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0016874 |text = ligase activity}} {{GNF_GO|id=GO:0017033 |text = DNA topoisomerase I binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0016607 |text = nuclear speck}}
-  | Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006512 |text = ubiquitin cycle}} {{GNF_GO|id=GO:0006915 |text = apoptosis}} {{GNF_GO|id=GO:0006974 |text = response to DNA damage stimulus}} {{GNF_GO|id=GO:0042127 |text = regulation of cell proliferation}} {{GNF_GO|id=GO:0045941 |text = positive regulation of transcription}} {{GNF_GO|id=GO:0051457 |text = maintenance of protein localization in nucleus}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 10210
-    | Hs_Ensembl = ENSG00000197579
-    | Hs_RefseqProtein = NP_005793
-    | Hs_RefseqmRNA = NM_005802
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 9
-    | Hs_GenLoc_start = 32530545
-    | Hs_GenLoc_end = 32542601
-    | Hs_Uniprot = Q9NS56
-    | Mm_EntrezGene = 106021
-    | Mm_Ensembl = ENSMUSG00000036822
-    | Mm_RefseqmRNA = NM_134097
-    | Mm_RefseqProtein = NP_598858
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 4
-    | Mm_GenLoc_start = 40448852
-    | Mm_GenLoc_end = 40457172
-    | Mm_Uniprot = Q05D01
-  }}
-}}
-'''Topoisomerase I binding, arginine/serine-rich''', also known as '''TOPORS''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TOPORS topoisomerase I binding, arginine/serine-rich| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10210| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 55: / Line 10: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Haluska P, Saleem A, Rasheed Z, ''et al.'' |title=Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein. |journal=Nucleic Acids Res. |volume=27 |issue= 12 |pages= 2538-44 |year= 1999 |pmid= 10352183 |doi=  }}
+*{{cite journal  | vauthors=Zhou R, Wen H, Ao SZ |title=Identification of a novel gene encoding a p53-associated protein. |journal=Gene |volume=235 |issue= 1–2 |pages= 93–101 |year= 1999 |pmid= 10415337 |doi=10.1016/S0378-1119(99)00203-6  }}
-*{{cite journal  | author=Zhou R, Wen H, Ao SZ |title=Identification of a novel gene encoding a p53-associated protein. |journal=Gene |volume=235 |issue= 1-2 |pages= 93-101 |year= 1999 |pmid= 10415337 |doi=  }}
+*{{cite journal   |vauthors=Souto-Carneiro MM, Krenn V, Hermann R, etal |title=IgVH genes from different anatomical regions, with different histopathological patterns, of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process |journal=Arthritis Res. |volume=2 |issue= 4 |pages= 303–14 |year= 2001 |pmid= 11056671 |doi=10.1186/ar105  | pmc=17813  }}
-*{{cite journal  | author=Souto-Carneiro MM, Krenn V, Hermann R, ''et al.'' |title=IgVH genes from different anatomical regions, with different histopathological patterns, of a rheumatoid arthritis patient suggest cyclic re-entry of mature synovial B-cells in the hypermutation process. |journal=Arthritis Res. |volume=2 |issue= 4 |pages= 303-14 |year= 2001 |pmid= 11056671 |doi=  }}
+*{{cite journal   |vauthors=Chu D, Kakazu N, Gorrin-Rivas MJ, etal |title=Cloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequence |journal=J. Biol. Chem. |volume=276 |issue= 17 |pages= 14004–13 |year= 2001 |pmid= 11278651 |doi= 10.1074/jbc.M010262200 }}
-*{{cite journal  | author=Chu D, Kakazu N, Gorrin-Rivas MJ, ''et al.'' |title=Cloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequence. |journal=J. Biol. Chem. |volume=276 |issue= 17 |pages= 14004-13 |year= 2001 |pmid= 11278651 |doi= 10.1074/jbc.M010262200 }}
+*{{cite journal  | vauthors=Weger S, Hammer E, Heilbronn R |title=Topors, a p53 and topoisomerase I binding protein, interacts with the adeno-associated virus (AAV-2) Rep78/68 proteins and enhances AAV-2 gene expression |journal=J. Gen. Virol. |volume=83 |issue= Pt 3 |pages= 511–6 |year= 2002 |pmid= 11842245 |doi=  10.1099/0022-1317-83-3-511}}
-*{{cite journal  | author=Weger S, Hammer E, Heilbronn R |title=Topors, a p53 and topoisomerase I binding protein, interacts with the adeno-associated virus (AAV-2) Rep78/68 proteins and enhances AAV-2 gene expression. |journal=J. Gen. Virol. |volume=83 |issue= Pt 3 |pages= 511-6 |year= 2002 |pmid= 11842245 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Rasheed ZA, Saleem A, Ravee Y, ''et al.'' |title=The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies. |journal=Exp. Cell Res. |volume=277 |issue= 2 |pages= 152-60 |year= 2002 |pmid= 12083797 |doi=  }}
+*{{cite journal   |vauthors=Imabayashi H, Mori T, Gojo S, etal |title=Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis |journal=Exp. Cell Res. |volume=288 |issue= 1 |pages= 35–50 |year= 2003 |pmid= 12878157 |doi=10.1016/S0014-4827(03)00130-7  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Weger S, Hammer E, Engstler M |title=The DNA topoisomerase I binding protein topors as a novel cellular target for SUMO-1 modification: characterization of domains necessary for subcellular localization and sumolation |journal=Exp. Cell Res. |volume=290 |issue= 1 |pages= 13–27 |year= 2003 |pmid= 14516784 |doi=10.1016/S0014-4827(03)00292-1  }}
-*{{cite journal  | author=Imabayashi H, Mori T, Gojo S, ''et al.'' |title=Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. |journal=Exp. Cell Res. |volume=288 |issue= 1 |pages= 35-50 |year= 2003 |pmid= 12878157 |doi=  }}
+*{{cite journal   |vauthors=Saleem A, Dutta J, Malegaonkar D, etal |title=The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor |journal=Oncogene |volume=23 |issue= 31 |pages= 5293–300 |year= 2004 |pmid= 15107820 |doi= 10.1038/sj.onc.1207700 }}
-*{{cite journal  | author=Weger S, Hammer E, Engstler M |title=The DNA topoisomerase I binding protein topors as a novel cellular target for SUMO-1 modification: characterization of domains necessary for subcellular localization and sumolation. |journal=Exp. Cell Res. |volume=290 |issue= 1 |pages= 13-27 |year= 2003 |pmid= 14516784 |doi=  }}
+*{{cite journal   |vauthors=Humphray SJ, Oliver K, Hunt AR, etal |title=DNA sequence and analysis of human chromosome 9 |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465  | pmc=2734081 }}
-*{{cite journal  | author=Saleem A, Dutta J, Malegaonkar D, ''et al.'' |title=The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor. |journal=Oncogene |volume=23 |issue= 31 |pages= 5293-300 |year= 2004 |pmid= 15107820 |doi= 10.1038/sj.onc.1207700 }}
+*{{cite journal   |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional proteomics mapping of a human signaling pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104  | pmc=442148 }}
-*{{cite journal  | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
+*{{cite journal   |vauthors=Rajendra R, Malegaonkar D, Pungaliya P, etal |title=Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53 |journal=J. Biol. Chem. |volume=279 |issue= 35 |pages= 36440–4 |year= 2004 |pmid= 15247280 |doi= 10.1074/jbc.C400300200 }}
-*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
+*{{cite journal   |vauthors=Beausoleil SA, Jedrychowski M, Schwartz D, etal |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 }}
-*{{cite journal  | author=Rajendra R, Malegaonkar D, Pungaliya P, ''et al.'' |title=Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53. |journal=J. Biol. Chem. |volume=279 |issue= 35 |pages= 36440-4 |year= 2004 |pmid= 15247280 |doi= 10.1074/jbc.C400300200 }}
+*{{cite journal   |vauthors=Oyanagi H, Takenaka K, Ishikawa S, etal |title=Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer |journal=Lung Cancer |volume=46 |issue= 1 |pages= 21–8 |year= 2005 |pmid= 15364129 |doi= 10.1016/j.lungcan.2004.03.009 }}
-*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Oyanagi H, Takenaka K, Ishikawa S, ''et al.'' |title=Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer. |journal=Lung Cancer |volume=46 |issue= 1 |pages= 21-8 |year= 2005 |pmid= 15364129 |doi= 10.1016/j.lungcan.2004.03.009 }}
+*{{cite journal   |vauthors=Flatten K, Dai NT, Vroman BT, etal |title=The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 14349–55 |year= 2005 |pmid= 15699047 |doi= 10.1074/jbc.M411890200 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Lin L, Ozaki T, Takada Y, etal |title=topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage |journal=Oncogene |volume=24 |issue= 21 |pages= 3385–96 |year= 2005 |pmid= 15735665 |doi= 10.1038/sj.onc.1208554 }}
-*{{cite journal  | author=Flatten K, Dai NT, Vroman BT, ''et al.'' |title=The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons. |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 14349-55 |year= 2005 |pmid= 15699047 |doi= 10.1074/jbc.M411890200 }}
+*{{cite journal  | vauthors=Weger S, Hammer E, Heilbronn R |title=Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo |journal=FEBS Lett. |volume=579 |issue= 22 |pages= 5007–12 |year= 2005 |pmid= 16122737 |doi= 10.1016/j.febslet.2005.07.088 }}
-*{{cite journal  | author=Lin L, Ozaki T, Takada Y, ''et al.'' |title=topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage. |journal=Oncogene |volume=24 |issue= 21 |pages= 3385-96 |year= 2005 |pmid= 15735665 |doi= 10.1038/sj.onc.1208554 }}
+*{{cite journal   |vauthors=Papaioannou M, Chakarova CF, Prescott DC, etal |title=A new locus (RP31) for autosomal dominant retinitis pigmentosa maps to chromosome 9p |journal=Hum. Genet. |volume=118 |issue= 3–4 |pages= 501–3 |year= 2006 |pmid= 16189705 |doi= 10.1007/s00439-005-0063-3 }}
-*{{cite journal  | author=Weger S, Hammer E, Heilbronn R |title=Topors acts as a SUMO-1 E3 ligase for p53 in vitro and in vivo. |journal=FEBS Lett. |volume=579 |issue= 22 |pages= 5007-12 |year= 2005 |pmid= 16122737 |doi= 10.1016/j.febslet.2005.07.088 }}
-*{{cite journal  | author=Papaioannou M, Chakarova CF, Prescott DC, ''et al.'' |title=A new locus (RP31) for autosomal dominant retinitis pigmentosa maps to chromosome 9p. |journal=Hum. Genet. |volume=118 |issue= 3-4 |pages= 501-3 |year= 2006 |pmid= 16189705 |doi= 10.1007/s00439-005-0063-3 }}
 }}
 {{refend}}
-{{protein-stub}}
+==External links==
-{{WikiDoc Sources}}
+* {{UCSC genome browser|TOPORS}}
+* {{UCSC gene details|TOPORS}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+{{gene-9-stub}}

TOPORS: Difference between revisions

Latest revision as of 07:32, 10 January 2019

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