PPP3R2: Difference between revisions
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'''Calcineurin subunit B type 2''' is a [[protein]] that in humans is encoded by the ''PPP3R2'' [[gene]].<ref name="pmid15865209">{{cite journal | vauthors = Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L | title = Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis | journal = Mol Biol Rep | volume = 32 | issue = 1 | pages = 41–5 |date=May 2005 | pmid = 15865209 | pmc = | doi =10.1007/s11033-004-4250-4 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5535| accessdate = }}</ref> Among its related pathways are [[MAPK/ERK pathway|MAPK signaling pathway]]<ref>{{Cite web|title = PathCards :: MAPK signaling pathway Pathway and related pathways|url = http://pathcards.genecards.org/card/mapk_signaling_pathway|website = pathcards.genecards.org|accessdate = 2015-09-08}}</ref> and [[GPCR pathway]].<ref>{{Cite web|title = PathCards :: GPCR Pathway Pathway and related pathways|url = http://pathcards.genecards.org/card/gpcr_pathway|website = pathcards.genecards.org|accessdate = 2015-09-08}}</ref> GO annotations related to this gene include calcium ion binding. An important paralog of this gene is [[CHP1]].<ref>{{Cite web|title = PPP3R2 Gene - GeneCards {{!}} CANB2 Protein {{!}} CANB2 Antibody|url = | '''Calcineurin subunit B type 2''' is a [[protein]] that in humans is encoded by the ''PPP3R2'' [[gene]].<ref name="pmid15865209">{{cite journal | vauthors = Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L | title = Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis | journal = Mol Biol Rep | volume = 32 | issue = 1 | pages = 41–5 |date=May 2005 | pmid = 15865209 | pmc = | doi =10.1007/s11033-004-4250-4 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5535| accessdate = }}</ref> Among its related pathways are [[MAPK/ERK pathway|MAPK signaling pathway]]<ref>{{Cite web|title = PathCards :: MAPK signaling pathway Pathway and related pathways|url = http://pathcards.genecards.org/card/mapk_signaling_pathway|website = pathcards.genecards.org|accessdate = 2015-09-08}}</ref> and [[GPCR pathway]].<ref>{{Cite web|title = PathCards :: GPCR Pathway Pathway and related pathways|url = http://pathcards.genecards.org/card/gpcr_pathway|website = pathcards.genecards.org|accessdate = 2015-09-08}}</ref> GO annotations related to this gene include calcium ion binding. An important paralog of this gene is [[CHP1]].<ref>{{Cite web|title = PPP3R2 Gene - GeneCards {{!}} CANB2 Protein {{!}} CANB2 Antibody|url = https://www.genecards.org/cgi-bin/carddisp.pl?gene=PPP3R2|website = www.genecards.org|accessdate = 2015-09-08|first = GeneCards Human Gene|last = Database}}</ref> | ||
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Latest revision as of 07:40, 10 January 2019
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Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene.[1][2] Among its related pathways are MAPK signaling pathway[3] and GPCR pathway.[4] GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CHP1.[5]
References
- ↑ Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L (May 2005). "Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis". Mol Biol Rep. 32 (1): 41–5. doi:10.1007/s11033-004-4250-4. PMID 15865209.
- ↑ "Entrez Gene: PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform".
- ↑ "PathCards :: MAPK signaling pathway Pathway and related pathways". pathcards.genecards.org. Retrieved 2015-09-08.
- ↑ "PathCards :: GPCR Pathway Pathway and related pathways". pathcards.genecards.org. Retrieved 2015-09-08.
- ↑ Database, GeneCards Human Gene. "PPP3R2 Gene - GeneCards | CANB2 Protein | CANB2 Antibody". www.genecards.org. Retrieved 2015-09-08.
Further reading
- Mukai H, Chang CD, Tanaka H, et al. (1991). "cDNA cloning of a novel testis-specific calcineurin B-like protein". Biochem. Biophys. Res. Commun. 179 (3): 1325–30. doi:10.1016/0006-291X(91)91718-R. PMID 1718268.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bennasser Y, Badou A, Tkaczuk J, Bahraoui E (2003). "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha". Virology. 303 (1): 174–80. doi:10.1006/viro.2002.1676. PMID 12482669.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Koefoed-Nielsen PB, Karamperis N, Højskov C, et al. (2007). "The calcineurin activity profiles of cyclosporin and tacrolimus are different in stable renal transplant patients". Transpl. Int. 19 (10): 821–7. doi:10.1111/j.1432-2277.2006.00359.x. PMID 16961774.
- Saeki M, Irie Y, Ni L, et al. (2007). "Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation". J. Biol. Chem. 282 (16): 11786–94. doi:10.1074/jbc.M609347200. PMID 17324936.
- Jang H, Cho EJ, Youn HD (2007). "A new calcineurin inhibition domain in Cabin1". Biochem. Biophys. Res. Commun. 359 (1): 129–35. doi:10.1016/j.bbrc.2007.05.066. PMID 17531200.
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