DCMP deaminase: Difference between revisions
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'''dCMP deaminase''' ({{EC number|3.5.4.12}}, ''deoxycytidylate deaminase'', ''deoxy-CMP-deaminase'', ''deoxycytidylate aminohydrolase'', ''deoxycytidine monophosphate deaminase'', ''deoxycytidine-5'-phosphate deaminase'', ''deoxycytidine-5'-monophosphate aminohydrolase'') is an enzyme which converts [[deoxycytidylic acid]] to [[deoxyuridylic acid]].<ref>{{cite journal | title = The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5 | '''dCMP deaminase''' ({{EC number|3.5.4.12}}, ''deoxycytidylate deaminase'', ''deoxy-CMP-deaminase'', ''deoxycytidylate aminohydrolase'', ''deoxycytidine monophosphate deaminase'', ''deoxycytidine-5'-phosphate deaminase'', ''deoxycytidine-5'-monophosphate aminohydrolase'') is an enzyme which converts [[deoxycytidylic acid]] to [[deoxyuridylic acid]].<ref>{{cite journal | vauthors = Scarano E | title = The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate | journal = The Journal of Biological Chemistry | volume = 235 | pages = 706–13 | date = March 1960 | pmid = 14442222 }}</ref><ref>{{cite journal | vauthors = Scarano E, Bonaduce L | title = The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine | journal = The Journal of Biological Chemistry | volume = 235 | pages = 3556–61 | date = December 1960 | pmid = 13747062 }}</ref><ref>{{cite journal | vauthors = Sergott RC, Debeer LJ, Bessman MJ | title = On the regulation of a bacterial deoxycytidylate deaminase | journal = The Journal of Biological Chemistry | volume = 246 | issue = 24 | pages = 7755–8 | date = December 1971 | pmid = 5002683 }}</ref> | ||
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==External links== | == External links == | ||
* {{MeshName|dCMP+deaminase}} | * {{MeshName|dCMP+deaminase}} | ||
Latest revision as of 11:53, 10 January 2019
| dCMP deaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| File:4p9e.jpg Deoxycytidylate deaminase hexamer, Cyanophage s-tim5 | |||||||||
| Identifiers | |||||||||
| EC number | 3.5.4.12 | ||||||||
| CAS number | 9026-92-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| dCMP deaminase | |
|---|---|
| Identifiers | |
| Symbol | DCTD |
| Entrez | 1635 |
| HUGO | 2710 |
| OMIM | 607638 |
| RefSeq | NM_001921 |
| UniProt | P32321 |
| Other data | |
| EC number | 3.5.4.12 |
| Locus | Chr. 4 q35.1 |
dCMP deaminase (EC 3.5.4.12, deoxycytidylate deaminase, deoxy-CMP-deaminase, deoxycytidylate aminohydrolase, deoxycytidine monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidine-5'-monophosphate aminohydrolase) is an enzyme which converts deoxycytidylic acid to deoxyuridylic acid.[1][2][3]
References
- ↑ Scarano E (March 1960). "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. I. The enzymatic deamination of deoxycytidine 5'-phosphate and of 5-methyldeoxycytidine 5-methyldeoxycytidine 5'-phosphate". The Journal of Biological Chemistry. 235: 706–13. PMID 14442222.
- ↑ Scarano E, Bonaduce L (December 1960). "The enzymatic deamination of 6-aminopyrimidine deoxyribonucleotides. II. Purification and properties of a 6-aminopyrimidine deoxyribonucleoside 5'-phosphate deaminase from unfertilized eggs of sea urchine". The Journal of Biological Chemistry. 235: 3556–61. PMID 13747062.
- ↑ Sergott RC, Debeer LJ, Bessman MJ (December 1971). "On the regulation of a bacterial deoxycytidylate deaminase". The Journal of Biological Chemistry. 246 (24): 7755–8. PMID 5002683.
External links
- dCMP+deaminase at the US National Library of Medicine Medical Subject Headings (MeSH)