PANK1: Difference between revisions

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{{PBB_Summary
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| summary_text = This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified.<ref name="entrez">{{cite web | title = Entrez Gene: PANK1 pantothenate kinase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53354| accessdate = }}</ref>
| summary_text = This gene encodes a [[protein]] belonging to the [[pantothenate kinase]] family. Pantothenate kinase is a key regulatory enzyme in the [[biosynthesis]] of [[coenzyme A]] (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through [[feedback inhibition]] by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct [[isoform]], have been identified.<ref name="entrez">{{cite web | title = Entrez Gene: PANK1 pantothenate kinase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=53354| accessdate = }}</ref>
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Latest revision as of 15:07, 14 February 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Pantothenate kinase 1 is an enzyme that in humans is encoded by the PANK1 gene.[1]

This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified.[1]

References

  1. 1.0 1.1 "Entrez Gene: PANK1 pantothenate kinase 1".

Further reading