POU2AF1: Difference between revisions

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Latest revision as of 03:54, 6 March 2018

POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.^[1]^[2]

Interactions

POU2AF1 has been shown to interact with:

POU2F1^[3]^[4]^[5] and
SIAH1.^[6]

References

↑ Junker S, Brøndum-Nielsen K, Newell JW, Matthias P, Tommerup N (Jun 1996). "Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization". Genomics. 33 (1): 143–5. doi:10.1006/geno.1996.0173. PMID 8617501.
↑ "Entrez Gene: POU2AF1 POU domain, class 2, associating factor 1".
↑ Chasman D, Cepek K, Sharp PA, Pabo CO (Oct 1999). "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev. 13 (20): 2650–7. doi:10.1101/gad.13.20.2650. PMC 317104. PMID 10541551.
↑ Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N (Jan 1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Mol. Cell. Biol. 18 (1): 368–77. doi:10.1128/mcb.18.1.368. PMC 121507. PMID 9418884.
↑ Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B (Jun 2001). "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator". Biochemistry. 40 (22): 6580–8. doi:10.1021/bi010095x. PMID 11380252.
↑ Tiedt R, Bartholdy BA, Matthias G, Newell JW, Matthias P (Aug 2001). "The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1". EMBO J. 20 (15): 4143–52. doi:10.1093/emboj/20.15.4143. PMC 149178. PMID 11483517.

Teitell MA (2004). "OCA-B regulation of B-cell development and function". Trends Immunol. 24 (10): 546–53. doi:10.1016/j.it.2003.08.002. PMID 14552839.
Luo Y, Roeder RG (1995). "Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B". Mol. Cell. Biol. 15 (8): 4115–24. PMC 230650. PMID 7623806.
Gstaiger M, Knoepfel L, Georgiev O, Schaffner W, Hovens CM (1995). "A B-cell coactivator of octamer-binding transcription factors". Nature. 373 (6512): 360–2. doi:10.1038/373360a0. PMID 7779176.
Strubin M, Newell JW, Matthias P (1995). "OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins". Cell. 80 (3): 497–506. doi:10.1016/0092-8674(95)90500-6. PMID 7859290.
Galiègue-Zouitina S, Quief S, Hildebrand MP, Denis C, Lecocq G, Collyn-d'Hooghe M, Bastard C, Yuille M, Dyer MJ, Kerckaert JP (1996). "Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation". Comptes Rendus de l'Académie des Sciences, Série III. 318 (11): 1125–31. PMID 8574789.
Zwilling S, Dieckmann A, Pfisterer P, Angel P, Wirth T (1997). "Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells". Science. 277 (5323): 221–5. doi:10.1126/science.277.5323.221. PMID 9211847.
Sauter P, Matthias P (1998). "The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction". Immunobiology. 198 (1–3): 207–16. doi:10.1016/S0171-2985(97)80041-1. PMID 9442392.
Luo Y, Ge H, Stevens S, Xiao H, Roeder RG (1998). "Coactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors". Mol. Cell. Biol. 18 (7): 3803–10. doi:10.1128/mcb.18.7.3803. PMC 108964. PMID 9632764.
Sauter P, Matthias P (1998). "Coactivator OBF-1 Makes Selective Contacts with Both the POU-Specific Domain and the POU Homeodomain and Acts as a Molecular Clamp on DNA". Mol. Cell. Biol. 18 (12): 7397–409. PMC 109321. PMID 9819426.
Chasman D, Cepek K, Sharp PA, Pabo CO (1999). "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev. 13 (20): 2650–7. doi:10.1101/gad.13.20.2650. PMC 317104. PMID 10541551.
Tomilin A, Reményi A, Lins K, Bak H, Leidel S, Vriend G, Wilmanns M, Schöler HR (2001). "Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration". Cell. 103 (6): 853–64. doi:10.1016/S0092-8674(00)00189-6. PMID 11136971.
Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B (2001). "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator". Biochemistry. 40 (22): 6580–8. doi:10.1021/bi010095x. PMID 11380252.
Tiedt R, Bartholdy BA, Matthias G, Newell JW, Matthias P (2001). "The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1". EMBO J. 20 (15): 4143–52. doi:10.1093/emboj/20.15.4143. PMC 149178. PMID 11483517.
Boehm J, He Y, Greiner A, Staudt L, Wirth T (2001). "Regulation of BOB.1/OBF.1 stability by SIAH". EMBO J. 20 (15): 4153–62. doi:10.1093/emboj/20.15.4153. PMC 149152. PMID 11483518.
Malone CS, Wall R (2002). "Bob1 (OCA-B/OBF-1) differential transactivation of the B cell-specific B29 (Ig beta) and mb-1 (Ig alpha) promoters". J. Immunol. 168 (7): 3369–75. doi:10.4049/jimmunol.168.7.3369. PMID 11907094.
Casellas R, Jankovic M, Meyer G, Gazumyan A, Luo Y, Roeder R, Nussenzweig M (2003). "OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genes". Cell. 110 (5): 575–85. doi:10.1016/S0092-8674(02)00911-X. PMID 12230975.
Schaffer A, Kim EC, Wu X, Zan H, Testoni L, Salamon S, Cerutti A, Casali P (2003). "Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements". J. Biol. Chem. 278 (25): 23141–50. doi:10.1074/jbc.M212952200. PMID 12672812.
Lins K, Reményi A, Tomilin A, Massa S, Wilmanns M, Matthias P, Schöler HR (2003). "OBF1 enhances transcriptional potential of Oct1". EMBO J. 22 (9): 2188–98. doi:10.1093/emboj/cdg199. PMC 156071. PMID 12727885.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[pmid8617501-1] Junker S, Brøndum-Nielsen K, Newell JW, Matthias P, Tommerup N (Jun 1996). "Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization". Genomics. 33 (1): 143–5. doi:10.1006/geno.1996.0173. PMID 8617501.

[entrez-2] "Entrez Gene: POU2AF1 POU domain, class 2, associating factor 1".

[pmid10541551-3] Chasman D, Cepek K, Sharp PA, Pabo CO (Oct 1999). "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev. 13 (20): 2650–7. doi:10.1101/gad.13.20.2650. PMC 317104. PMID 10541551.

[pmid9418884-4] Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N (Jan 1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Mol. Cell. Biol. 18 (1): 368–77. doi:10.1128/mcb.18.1.368. PMC 121507. PMID 9418884.

[pmid11380252-5] Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B (Jun 2001). "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator". Biochemistry. 40 (22): 6580–8. doi:10.1021/bi010095x. PMID 11380252.

[pmid11483517-6] Tiedt R, Bartholdy BA, Matthias G, Newell JW, Matthias P (Aug 2001). "The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1". EMBO J. 20 (15): 4143–52. doi:10.1093/emboj/20.15.4143. PMC 149178. PMID 11483517.

[1]

[2]

[3]

[4]

[5]

[6]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''POU domain class 2-associating factor 1''' is a [[protein]] that in humans is encoded by the ''POU2AF1'' [[gene]].<ref name="pmid8617501">{{cite journal | vauthors = Junker S, Brøndum-Nielsen K, Newell JW, Matthias P, Tommerup N | title = Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization | journal = Genomics | volume = 33 | issue = 1 | pages = 143–5 | date = Jun 1996 | pmid = 8617501 | pmc =  | doi = 10.1006/geno.1996.0173 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: POU2AF1 POU domain, class 2, associating factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5450| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{GNF_Protein_box
- | image = PBB_Protein_POU2AF1_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1cqt.
- | PDB = {{PDB2|1cqt}}
- | Name = POU domain, class 2, associating factor 1
- | HGNCid = 9211
- | Symbol = POU2AF1
- | AltSymbols =; BOB1; OBF-1; OBF1; OCAB
- | OMIM = 601206
- | ECnumber =
- | Homologene = 4543
- | MGIid = 105086
- | GeneAtlas_image1 = PBB_GE_POU2AF1_205267_at_tn.png
- | Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003713 |text = transcription coactivator activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006959 |text = humoral immune response}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 5450
-    | Hs_Ensembl = ENSG00000110777
-    | Hs_RefseqProtein = NP_006226
-    | Hs_RefseqmRNA = NM_006235
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 11
-    | Hs_GenLoc_start = 110728210
-    | Hs_GenLoc_end = 110755627
-    | Hs_Uniprot = Q16633
-    | Mm_EntrezGene = 18985
-    | Mm_Ensembl = ENSMUSG00000032053
-    | Mm_RefseqmRNA = NM_011136
-    | Mm_RefseqProtein = NP_035266
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 9
-    | Mm_GenLoc_start = 50965920
-    | Mm_GenLoc_end = 50992309
-    | Mm_Uniprot = Q542H4
-  }}
-}}
-'''POU domain, class 2, associating factor 1''', also known as '''POU2AF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: POU2AF1 POU domain, class 2, associating factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5450| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+POU2AF1 has been shown to [[Protein-protein interaction|interact]] with:
-{{PBB_Summary
+* [[POU2F1]]<ref name = pmid10541551>{{cite journal | vauthors = Chasman D, Cepek K, Sharp PA, Pabo CO | title = Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface | journal = Genes Dev. | volume = 13 | issue = 20 | pages = 2650–7 | date = Oct 1999 | pmid = 10541551 | pmc = 317104 | doi =  10.1101/gad.13.20.2650}}</ref><ref name = pmid9418884>{{cite journal | vauthors = Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N | title = The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1 | journal = Mol. Cell. Biol. | volume = 18 | issue = 1 | pages = 368–77 | date = Jan 1998 | pmid = 9418884 | pmc = 121507 | doi =  10.1128/mcb.18.1.368}}</ref><ref name = pmid11380252>{{cite journal | vauthors = Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B | title = Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator | journal = Biochemistry | volume = 40 | issue = 22 | pages = 6580–8 | date = Jun 2001 | pmid = 11380252 | doi =  10.1021/bi010095x}}</ref>  and
-| section_title =
+* [[SIAH1]].<ref name = pmid11483517>{{cite journal | vauthors = Tiedt R, Bartholdy BA, Matthias G, Newell JW, Matthias P | title = The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1 | journal = EMBO J. | volume = 20 | issue = 15 | pages = 4143–52 | date = Aug 2001 | pmid = 11483517 | pmc = 149178 | doi = 10.1093/emboj/20.15.4143 }}</ref>
-| summary_text =
-}}
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Teitell MA | title = OCA-B regulation of B-cell development and function | journal = Trends Immunol. | volume = 24 | issue = 10 | pages = 546–53 | year = 2004 | pmid = 14552839 | doi = 10.1016/j.it.2003.08.002 }}
-| citations =
+* {{cite journal | vauthors = Luo Y, Roeder RG | title = Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B | journal = Mol. Cell. Biol. | volume = 15 | issue = 8 | pages = 4115–24 | year = 1995 | pmid = 7623806 | pmc = 230650 | doi =  }}
-*{{cite journal  | author=Teitell MA |title=OCA-B regulation of B-cell development and function. |journal=Trends Immunol. |volume=24 |issue= 10 |pages= 546-53 |year= 2004 |pmid= 14552839 |doi=  }}
+* {{cite journal | vauthors = Gstaiger M, Knoepfel L, Georgiev O, Schaffner W, Hovens CM | title = A B-cell coactivator of octamer-binding transcription factors | journal = Nature | volume = 373 | issue = 6512 | pages = 360–2 | year = 1995 | pmid = 7779176 | doi = 10.1038/373360a0 }}
-*{{cite journal  | author=Luo Y, Roeder RG |title=Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. |journal=Mol. Cell. Biol. |volume=15 |issue= 8 |pages= 4115-24 |year= 1995 |pmid= 7623806 |doi=  }}
+* {{cite journal | vauthors = Strubin M, Newell JW, Matthias P | title = OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins | journal = Cell | volume = 80 | issue = 3 | pages = 497–506 | year = 1995 | pmid = 7859290 | doi = 10.1016/0092-8674(95)90500-6 }}
-*{{cite journal  | author=Gstaiger M, Knoepfel L, Georgiev O, ''et al.'' |title=A B-cell coactivator of octamer-binding transcription factors. |journal=Nature |volume=373 |issue= 6512 |pages= 360-2 |year= 1995 |pmid= 7779176 |doi= 10.1038/373360a0 }}
+* {{cite journal | vauthors = Galiègue-Zouitina S, Quief S, Hildebrand MP, Denis C, Lecocq G, Collyn-d'Hooghe M, Bastard C, Yuille M, Dyer MJ, Kerckaert JP | title = Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation | journal = Comptes Rendus de l'Académie des Sciences, Série III | volume = 318 | issue = 11 | pages = 1125–31 | year = 1996 | pmid = 8574789 | doi =  }}
-*{{cite journal  | author=Strubin M, Newell JW, Matthias P |title=OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. |journal=Cell |volume=80 |issue= 3 |pages= 497-506 |year= 1995 |pmid= 7859290 |doi=  }}
+* {{cite journal | vauthors = Zwilling S, Dieckmann A, Pfisterer P, Angel P, Wirth T | title = Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells | journal = Science | volume = 277 | issue = 5323 | pages = 221–5 | year = 1997 | pmid = 9211847 | doi = 10.1126/science.277.5323.221 }}
-*{{cite journal  | author=Galiègue-Zouitina S, Quief S, Hildebrand MP, ''et al.'' |title=Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation. |journal=C. R. Acad. Sci. III, Sci. Vie |volume=318 |issue= 11 |pages= 1125-31 |year= 1996 |pmid= 8574789 |doi=  }}
+* {{cite journal | vauthors = Sauter P, Matthias P | title = The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction | journal = Immunobiology | volume = 198 | issue = 1–3 | pages = 207–16 | year = 1998 | pmid = 9442392 | doi = 10.1016/S0171-2985(97)80041-1 }}
-*{{cite journal  | author=Junker S, Brøndum-Nielsen K, Newell JW, ''et al.'' |title=Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization. |journal=Genomics |volume=33 |issue= 1 |pages= 143-5 |year= 1996 |pmid= 8617501 |doi= 10.1006/geno.1996.0173 }}
+* {{cite journal | vauthors = Luo Y, Ge H, Stevens S, Xiao H, Roeder RG | title = Coactivation by OCA-B: Definition of Critical Regions and Synergism with General Cofactors | journal = Mol. Cell. Biol. | volume = 18 | issue = 7 | pages = 3803–10 | year = 1998 | pmid = 9632764 | pmc = 108964 | doi =  10.1128/mcb.18.7.3803}}
-*{{cite journal  | author=Zwilling S, Dieckmann A, Pfisterer P, ''et al.'' |title=Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells. |journal=Science |volume=277 |issue= 5323 |pages= 221-5 |year= 1997 |pmid= 9211847 |doi=  }}
+* {{cite journal | vauthors = Sauter P, Matthias P | title = Coactivator OBF-1 Makes Selective Contacts with Both the POU-Specific Domain and the POU Homeodomain and Acts as a Molecular Clamp on DNA | journal = Mol. Cell. Biol. | volume = 18 | issue = 12 | pages = 7397–409 | year = 1998 | pmid = 9819426 | pmc = 109321 | doi =  }}
-*{{cite journal  | author=Sauter P, Matthias P |title=The B cell-specific coactivator OBF-1 (OCA-B, Bob-1) is inducible in T cells and its expression is dispensable for IL-2 gene induction. |journal=Immunobiology |volume=198 |issue= 1-3 |pages= 207-16 |year= 1998 |pmid= 9442392 |doi=  }}
+* {{cite journal | vauthors = Chasman D, Cepek K, Sharp PA, Pabo CO | title = Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface | journal = Genes Dev. | volume = 13 | issue = 20 | pages = 2650–7 | year = 1999 | pmid = 10541551 | pmc = 317104 | doi = 10.1101/gad.13.20.2650 }}
-*{{cite journal  | author=Luo Y, Ge H, Stevens S, ''et al.'' |title=Coactivation by OCA-B: definition of critical regions and synergism with general cofactors. |journal=Mol. Cell. Biol. |volume=18 |issue= 7 |pages= 3803-10 |year= 1998 |pmid= 9632764 |doi=  }}
+* {{cite journal | vauthors = Tomilin A, Reményi A, Lins K, Bak H, Leidel S, Vriend G, Wilmanns M, Schöler HR | title = Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration | journal = Cell | volume = 103 | issue = 6 | pages = 853–64 | year = 2001 | pmid = 11136971 | doi = 10.1016/S0092-8674(00)00189-6 }}
-*{{cite journal  | author=Sauter P, Matthias P |title=Coactivator OBF-1 makes selective contacts with both the POU-specific domain and the POU homeodomain and acts as a molecular clamp on DNA. |journal=Mol. Cell. Biol. |volume=18 |issue= 12 |pages= 7397-409 |year= 1998 |pmid= 9819426 |doi=  }}
+* {{cite journal | vauthors = Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B | title = Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator | journal = Biochemistry | volume = 40 | issue = 22 | pages = 6580–8 | year = 2001 | pmid = 11380252 | doi = 10.1021/bi010095x }}
-*{{cite journal  | author=Chasman D, Cepek K, Sharp PA, Pabo CO |title=Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. |journal=Genes Dev. |volume=13 |issue= 20 |pages= 2650-7 |year= 1999 |pmid= 10541551 |doi=  }}
+* {{cite journal | vauthors = Tiedt R, Bartholdy BA, Matthias G, Newell JW, Matthias P | title = The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1 | journal = EMBO J. | volume = 20 | issue = 15 | pages = 4143–52 | year = 2001 | pmid = 11483517 | pmc = 149178 | doi = 10.1093/emboj/20.15.4143 }}
-*{{cite journal  | author=Tomilin A, Reményi A, Lins K, ''et al.'' |title=Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration. |journal=Cell |volume=103 |issue= 6 |pages= 853-64 |year= 2001 |pmid= 11136971 |doi=  }}
+* {{cite journal | vauthors = Boehm J, He Y, Greiner A, Staudt L, Wirth T | title = Regulation of BOB.1/OBF.1 stability by SIAH | journal = EMBO J. | volume = 20 | issue = 15 | pages = 4153–62 | year = 2001 | pmid = 11483518 | pmc = 149152 | doi = 10.1093/emboj/20.15.4153 }}
-*{{cite journal  | author=Lee L, Stollar E, Chang J, ''et al.'' |title=Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator. |journal=Biochemistry |volume=40 |issue= 22 |pages= 6580-8 |year= 2001 |pmid= 11380252 |doi=  }}
+* {{cite journal | vauthors = Malone CS, Wall R | title = Bob1 (OCA-B/OBF-1) differential transactivation of the B cell-specific B29 (Ig beta) and mb-1 (Ig alpha) promoters | journal = J. Immunol. | volume = 168 | issue = 7 | pages = 3369–75 | year = 2002 | pmid = 11907094 | doi = 10.4049/jimmunol.168.7.3369 }}
-*{{cite journal  | author=Tiedt R, Bartholdy BA, Matthias G, ''et al.'' |title=The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1. |journal=EMBO J. |volume=20 |issue= 15 |pages= 4143-52 |year= 2001 |pmid= 11483517 |doi= 10.1093/emboj/20.15.4143 }}
+* {{cite journal | vauthors = Casellas R, Jankovic M, Meyer G, Gazumyan A, Luo Y, Roeder R, Nussenzweig M | title = OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genes | journal = Cell | volume = 110 | issue = 5 | pages = 575–85 | year = 2003 | pmid = 12230975 | doi = 10.1016/S0092-8674(02)00911-X }}
-*{{cite journal  | author=Boehm J, He Y, Greiner A, ''et al.'' |title=Regulation of BOB.1/OBF.1 stability by SIAH. |journal=EMBO J. |volume=20 |issue= 15 |pages= 4153-62 |year= 2001 |pmid= 11483518 |doi= 10.1093/emboj/20.15.4153 }}
+* {{cite journal | vauthors = Schaffer A, Kim EC, Wu X, Zan H, Testoni L, Salamon S, Cerutti A, Casali P | title = Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements | journal = J. Biol. Chem. | volume = 278 | issue = 25 | pages = 23141–50 | year = 2003 | pmid = 12672812 | doi = 10.1074/jbc.M212952200 }}
-*{{cite journal  | author=Malone CS, Wall R |title=Bob1 (OCA-B/OBF-1) differential transactivation of the B cell-specific B29 (Ig beta) and mb-1 (Ig alpha) promoters. |journal=J. Immunol. |volume=168 |issue= 7 |pages= 3369-75 |year= 2002 |pmid= 11907094 |doi=  }}
+* {{cite journal | vauthors = Lins K, Reményi A, Tomilin A, Massa S, Wilmanns M, Matthias P, Schöler HR | title = OBF1 enhances transcriptional potential of Oct1 | journal = EMBO J. | volume = 22 | issue = 9 | pages = 2188–98 | year = 2003 | pmid = 12727885 | pmc = 156071 | doi = 10.1093/emboj/cdg199 }}
-*{{cite journal  | author=Casellas R, Jankovic M, Meyer G, ''et al.'' |title=OcaB is required for normal transcription and V(D)J recombination of a subset of immunoglobulin kappa genes. |journal=Cell |volume=110 |issue= 5 |pages= 575-85 |year= 2003 |pmid= 12230975 |doi=  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Schaffer A, Kim EC, Wu X, ''et al.'' |title=Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements. |journal=J. Biol. Chem. |volume=278 |issue= 25 |pages= 23141-50 |year= 2003 |pmid= 12672812 |doi= 10.1074/jbc.M212952200 }}
-*{{cite journal  | author=Lins K, Reményi A, Tomilin A, ''et al.'' |title=OBF1 enhances transcriptional potential of Oct1. |journal=EMBO J. |volume=22 |issue= 9 |pages= 2188-98 |year= 2003 |pmid= 12727885 |doi= 10.1093/emboj/cdg199 }}
-}}
 {{refend}}
-{{protein-stub}}
+{{PDB Gallery|geneid=5450}}
-{{WikiDoc Sources}}
+{{gene-11-stub}}

POU2AF1: Difference between revisions

Latest revision as of 03:54, 6 March 2018

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