COPS7A: Difference between revisions

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{{Underlinked|date=May 2016}}
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{{Infobox_gene}}
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'''COP9 signalosome complex subunit 7a''' is a [[protein]] that in humans is encoded by the ''COPS7A'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: COPS7A COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50813| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
| HGNCid = 16758
| Symbol = COPS7A
| AltSymbols =; MGC110877
| OMIM = 
| ECnumber = 
| Homologene = 22685
| MGIid = 1349400
| GeneAtlas_image1 = PBB_GE_COPS7A_209029_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0008180 |text = signalosome}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 50813
    | Hs_Ensembl = ENSG00000111652
    | Hs_RefseqProtein = NP_057403
    | Hs_RefseqmRNA = NM_016319
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 6703473
    | Hs_GenLoc_end = 6711283
    | Hs_Uniprot = Q9UBW8
    | Mm_EntrezGene = 26894
    | Mm_Ensembl = ENSMUSG00000030127
    | Mm_RefseqmRNA = NM_012003
    | Mm_RefseqProtein = NP_036133
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 124924435
    | Mm_GenLoc_end = 124930994
    | Mm_Uniprot = Q9CZ04
  }}
}}
'''COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)''', also known as '''COPS7A''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: COPS7A COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50813| accessdate = }}</ref>
 
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==References==
{{reflist}}
==External links==
* {{UCSC gene info|COPS7A}}


==References==
{{reflist|2}}
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Wolf DA, Zhou C, Wee S |title=The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases? |journal=Nat. Cell Biol. |volume=5 |issue= 12 |pages= 1029-33 |year= 2004 |pmid= 14647295 |doi= 10.1038/ncb1203-1029 }}
*{{cite journal  | vauthors=Wolf DA, Zhou C, Wee S |title=The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases? |journal=Nat. Cell Biol. |volume=5 |issue= 12 |pages= 1029–33 |year= 2004 |pmid= 14647295 |doi= 10.1038/ncb1203-1029 }}
*{{cite journal  | author=Seeger M, Kraft R, Ferrell K, ''et al.'' |title=A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. |journal=FASEB J. |volume=12 |issue= 6 |pages= 469-78 |year= 1998 |pmid= 9535219 |doi= }}
*{{cite journal  | author=Seeger M |title=A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits |journal=FASEB J. |volume=12 |issue= 6 |pages= 469–78 |year= 1998 |pmid= 9535219 |doi=  |name-list-format=vanc| author2=Kraft R  | author3=Ferrell K  | display-authors=3  | last4=Bech-Otschir  | first4=D  | last5=Dumdey  | first5=R  | last6=Schade  | first6=R  | last7=Gordon  | first7=C | last8=Naumann  | first8=M  | last9=Dubiel  | first9=W  }}
*{{cite journal | author=Wei N, Tsuge T, Serino G, ''et al.'' |title=The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex. |journal=Curr. Biol. |volume=8 |issue= 16 |pages= 919-22 |year= 1998 |pmid= 9707402 |doi=  }}
*{{cite journal  | author=Wei N |title=The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex |journal=Curr. Biol. |volume=8 |issue= 16 |pages= 919–22 |year= 1998 |pmid= 9707402 |doi=10.1016/S0960-9822(07)00372-7  |name-list-format=vanc| author2=Tsuge T  | author3=Serino G | display-authors=3  | last4=Dohmae  | first4=Naoshi  | last5=Takio  | first5=Koji  | last6=Matsui  | first6=Minami  | last7=Deng  | first7=Xing-Wang  }}
*{{cite journal  | author=Bech-Otschir D, Kraft R, Huang X, ''et al.'' |title=COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. |journal=EMBO J. |volume=20 |issue= 7 |pages= 1630-9 |year= 2001 |pmid= 11285227 |doi= 10.1093/emboj/20.7.1630 }}
*{{cite journal  | author=Bech-Otschir D |title=COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system |journal=EMBO J. |volume=20 |issue= 7 |pages= 1630–9 |year= 2001 |pmid= 11285227 |doi= 10.1093/emboj/20.7.1630 | pmc=145508  |name-list-format=vanc| author2=Kraft R  | author3=Huang X  | display-authors=3  | last4=Henklein  | first4=P  | last5=Kapelari  | first5=B  | last6=Pollmann  | first6=C  | last7=Dubiel | first7=W }}
*{{cite journal | author=Lyapina S, Cope G, Shevchenko A, ''et al.'' |title=Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. |journal=Science |volume=292 |issue= 5520 |pages= 1382-5 |year= 2001 |pmid= 11337588 |doi= 10.1126/science.1059780 }}
*{{cite journal  | author=Lyapina S |title=Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome |journal=Science |volume=292 |issue= 5520 |pages= 1382–5 |year= 2001 |pmid= 11337588 |doi= 10.1126/science.1059780 |name-list-format=vanc| author2=Cope G | author3=Shevchenko A  | display-authors=3  | last4=Serino  | first4=G  | last5=Tsuge  | first5=T  | last6=Zhou  | first6=C  | last7=Wolf | first7=DA | last8=Wei  | first8=N  | last9=Shevchenko  | first9=A }}
*{{cite journal  | author=Wang Y, Devereux W, Stewart TM, Casero RA |title=Polyamine-modulated factor 1 binds to the human homologue of the 7a subunit of the Arabidopsis COP9 signalosome: implications in gene expression. |journal=Biochem. J. |volume=366 |issue= Pt 1 |pages= 79-86 |year= 2002 |pmid= 12020345 |doi= 10.1042/BJ20020211 }}
*{{cite journal | vauthors=Wang Y, Devereux W, Stewart TM, Casero RA |title=Polyamine-modulated factor 1 binds to the human homologue of the 7a subunit of the Arabidopsis COP9 signalosome: implications in gene expression |journal=Biochem. J. |volume=366 |issue= Pt 1 |pages= 79–86 |year= 2002 |pmid= 12020345 |doi= 10.1042/BJ20020211  | pmc=1222765 }}
*{{cite journal | author=Hoareau Alves K, Bochard V, Réty S, Jalinot P |title=Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome. |journal=FEBS Lett. |volume=527 |issue= 1-3 |pages= 15-21 |year= 2002 |pmid= 12220626 |doi=  }}
*{{cite journal  | vauthors=Hoareau Alves K, Bochard V, Réty S, Jalinot P |title=Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome |journal=FEBS Lett. |volume=527 |issue= 1–3 |pages= 15–21 |year= 2002 |pmid= 12220626 |doi=10.1016/S0014-5793(02)03147-2 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal | author=Serino G, Su H, Peng Z, ''et al.'' |title=Characterization of the last subunit of the Arabidopsis COP9 signalosome: implications for the overall structure and origin of the complex. |journal=Plant Cell |volume=15 |issue= 3 |pages= 719-31 |year= 2003 |pmid= 12615944 |doi=  }}
*{{cite journal | author=Serino G |title=Characterization of the Last Subunit of the Arabidopsis COP9 Signalosome: Implications for the Overall Structure and Origin of the Complex |journal=Plant Cell |volume=15 |issue= 3 |pages= 719–31 |year= 2003 |pmid= 12615944 |doi=10.1105/tpc.009092 | pmc=150025  |name-list-format=vanc| author2=Su H  | author3=Peng Z  | display-authors=3  | last4=Tsuge  | first4=T  | last5=Wei  | first5=N  | last6=Gu  | first6=H  | last7=Deng  | first7=XW  }}
*{{cite journal | author=Uhle S, Medalia O, Waldron R, ''et al.'' |title=Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. |journal=EMBO J. |volume=22 |issue= 6 |pages= 1302-12 |year= 2003 |pmid= 12628923 |doi= 10.1093/emboj/cdg127 }}
*{{cite journal  | author=Uhle S |title=Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome |journal=EMBO J. |volume=22 |issue= 6 |pages= 1302–12 |year= 2003 |pmid= 12628923 |doi= 10.1093/emboj/cdg127  | pmc=151059  |name-list-format=vanc| author2=Medalia O  | author3=Waldron R  | display-authors=3  | last4=Dumdey  | first4=R  | last5=Henklein  | first5=P  | last6=Bech-Otschir  | first6=D  | last7=Huang  | first7=X  | last8=Berse  | first8=M  | last9=Sperling  | first9=J }}
*{{cite journal  | author=Groisman R, Polanowska J, Kuraoka I, ''et al.'' |title=The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. |journal=Cell |volume=113 |issue= 3 |pages= 357-67 |year= 2003 |pmid= 12732143 |doi=  }}
*{{cite journal  | author=Groisman R |title=The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage |journal=Cell |volume=113 |issue= 3 |pages= 357–67 |year= 2003 |pmid= 12732143 |doi=10.1016/S0092-8674(03)00316-7  |name-list-format=vanc| author2=Polanowska J  | author3=Kuraoka I  | display-authors=3  | last4=Sawada  | first4=Jun-Ichi  | last5=Saijo  | first5=Masafumi  | last6=Drapkin  | first6=Ronny  | last7=Kisselev  | first7=Alexei F.  | last8=Tanaka  | first8=Kiyoji  | last9=Nakatani  | first9=Yoshihiro  }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal | author=Obuse C, Iwasaki O, Kiyomitsu T, ''et al.'' |title=A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. |journal=Nat. Cell Biol. |volume=6 |issue= 11 |pages= 1135-41 |year= 2004 |pmid= 15502821 |doi= 10.1038/ncb1187 }}
*{{cite journal  | author=Obuse C |title=A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1 |journal=Nat. Cell Biol. |volume=6 |issue= 11 |pages= 1135–41 |year= 2004 |pmid= 15502821 |doi= 10.1038/ncb1187  |name-list-format=vanc| author2=Iwasaki O  | author3=Kiyomitsu T  | display-authors=3  | last4=Goshima  | first4=Gohta  | last5=Toyoda  | first5=Yusuke  | last6=Yanagida  | first6=Mitsuhiro }}
*{{cite journal | author=Stelzl U, Worm U, Lalowski M, ''et al.'' |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957-68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 }}
*{{cite journal  | author=Stelzl U |title=A human protein-protein interaction network: a resource for annotating the proteome |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029  |name-list-format=vanc| author2=Worm U  | author3=Lalowski M  | display-authors=3  | last4=Haenig  | first4=Christian  | last5=Brembeck  | first5=Felix H.  | last6=Goehler  | first6=Heike  | last7=Stroedicke  | first7=Martin  | last8=Zenkner  | first8=Martina  | last9=Schoenherr  | first9=Anke }}
}}
}}
{{refend}}
{{refend}}


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Latest revision as of 01:01, 15 December 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

COP9 signalosome complex subunit 7a is a protein that in humans is encoded by the COPS7A gene.[1]

References

  1. ↑ "Entrez Gene: COPS7A COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)".

External links

Further reading



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