SF3A2: Difference between revisions
Jump to navigation
Jump to search
m (Bot: HTTP→HTTPS) |
imported>JCW-CleanerBot m (→Further reading: task, replaced: journal = Rna → journal = RNA (2)) |
||
| Line 16: | Line 16: | ||
{{refbegin|33em}} | {{refbegin|33em}} | ||
* {{cite journal | vauthors = Chiara MD, Champion-Arnaud P, Buvoli M, Nadal-Ginard B, Reed R | title = Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 91 | issue = 14 | pages = 6403–7 | date = July 1994 | pmid = 8022796 | pmc = 44210 | doi = 10.1073/pnas.91.14.6403 }} | * {{cite journal | vauthors = Chiara MD, Champion-Arnaud P, Buvoli M, Nadal-Ginard B, Reed R | title = Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 91 | issue = 14 | pages = 6403–7 | date = July 1994 | pmid = 8022796 | pmc = 44210 | doi = 10.1073/pnas.91.14.6403 }} | ||
* {{cite journal | vauthors = Rain JC, Tartakoff AM, Krämer A, Legrain P | title = Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution | journal = | * {{cite journal | vauthors = Rain JC, Tartakoff AM, Krämer A, Legrain P | title = Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution | journal = RNA | volume = 2 | issue = 6 | pages = 535–50 | date = June 1996 | pmid = 8718683 | pmc = 1369393 | doi = }} | ||
* {{cite journal | vauthors = Hong W, Bennett M, Xiao Y, Feld Kramer R, Wang C, Reed R | title = Association of U2 snRNP with the spliceosomal complex E | journal = Nucleic Acids Research | volume = 25 | issue = 2 | pages = 354–61 | date = January 1997 | pmid = 9016565 | pmc = 146436 | doi = 10.1093/nar/25.2.354 }} | * {{cite journal | vauthors = Hong W, Bennett M, Xiao Y, Feld Kramer R, Wang C, Reed R | title = Association of U2 snRNP with the spliceosomal complex E | journal = Nucleic Acids Research | volume = 25 | issue = 2 | pages = 354–61 | date = January 1997 | pmid = 9016565 | pmc = 146436 | doi = 10.1093/nar/25.2.354 }} | ||
* {{cite journal | vauthors = Moraitou M, Patrinou-Georgoula M, Guialis A | title = Structural/functional properties of a mammalian multi-component structure containing all major spliceosomal small nuclear ribonucleoprotein particles | journal = The Biochemical Journal | volume = 332 ( Pt 1) | issue = 1 | pages = 135–44 | date = May 1998 | pmid = 9576861 | pmc = 1219461 | doi = }} | * {{cite journal | vauthors = Moraitou M, Patrinou-Georgoula M, Guialis A | title = Structural/functional properties of a mammalian multi-component structure containing all major spliceosomal small nuclear ribonucleoprotein particles | journal = The Biochemical Journal | volume = 332 ( Pt 1) | issue = 1 | pages = 135–44 | date = May 1998 | pmid = 9576861 | pmc = 1219461 | doi = }} | ||
| Line 26: | Line 26: | ||
* {{cite journal | vauthors = Nesic D, Krämer A | title = Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation | journal = Molecular and Cellular Biology | volume = 21 | issue = 19 | pages = 6406–17 | date = October 2001 | pmid = 11533230 | pmc = 99788 | doi = 10.1128/MCB.21.19.6406-6417.2001 }} | * {{cite journal | vauthors = Nesic D, Krämer A | title = Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation | journal = Molecular and Cellular Biology | volume = 21 | issue = 19 | pages = 6406–17 | date = October 2001 | pmid = 11533230 | pmc = 99788 | doi = 10.1128/MCB.21.19.6406-6417.2001 }} | ||
* {{cite journal | vauthors = Dresser DW, Jamin SP, Atkins CJ, Guerrier D | title = An expressed GNRP-like gene shares a bi-directional promoter with SF3A2 (SAP62) immediately upstream of AMH | journal = Gene | volume = 277 | issue = 1-2 | pages = 163–73 | date = October 2001 | pmid = 11602354 | doi = 10.1016/S0378-1119(01)00690-4 }} | * {{cite journal | vauthors = Dresser DW, Jamin SP, Atkins CJ, Guerrier D | title = An expressed GNRP-like gene shares a bi-directional promoter with SF3A2 (SAP62) immediately upstream of AMH | journal = Gene | volume = 277 | issue = 1-2 | pages = 163–73 | date = October 2001 | pmid = 11602354 | doi = 10.1016/S0378-1119(01)00690-4 }} | ||
* {{cite journal | vauthors = Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ | title = Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis | journal = | * {{cite journal | vauthors = Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ | title = Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis | journal = RNA | volume = 8 | issue = 4 | pages = 426–39 | date = April 2002 | pmid = 11991638 | pmc = 1370266 | doi = 10.1017/S1355838202021088 }} | ||
* {{cite journal | vauthors = Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Lührmann R | title = Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein | journal = The EMBO Journal | volume = 21 | issue = 18 | pages = 4978–88 | date = September 2002 | pmid = 12234937 | pmc = 126279 | doi = 10.1093/emboj/cdf480 }} | * {{cite journal | vauthors = Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Lührmann R | title = Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein | journal = The EMBO Journal | volume = 21 | issue = 18 | pages = 4978–88 | date = September 2002 | pmid = 12234937 | pmc = 126279 | doi = 10.1093/emboj/cdf480 }} | ||
* {{cite journal | vauthors = Takenaka K, Nakagawa H, Miyamoto S, Miki H | title = The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein | journal = The Biochemical Journal | volume = 382 | issue = Pt 1 | pages = 223–30 | date = August 2004 | pmid = 15142036 | pmc = 1133934 | doi = 10.1042/BJ20040521 }} | * {{cite journal | vauthors = Takenaka K, Nakagawa H, Miyamoto S, Miki H | title = The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein | journal = The Biochemical Journal | volume = 382 | issue = Pt 1 | pages = 223–30 | date = August 2004 | pmid = 15142036 | pmc = 1133934 | doi = 10.1042/BJ20040521 }} | ||
* {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Research | volume = 14 | issue = 7 | pages = 1324–32 | date = July 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }} | * {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Research | volume = 14 | issue = 7 | pages = 1324–32 | date = July 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }} | ||
* {{cite journal | vauthors = Nesic D, Tanackovic G, Krämer A | title = A role for Cajal bodies in the final steps of U2 snRNP biogenesis | journal = Journal of Cell Science | volume = 117 | issue = Pt 19 | pages = 4423–33 | date = September 2004 | pmid = 15316075 | doi = 10.1242/jcs.01308 }} | * {{cite journal | vauthors = Nesic D, Tanackovic G, Krämer A | title = A role for Cajal bodies in the final steps of U2 snRNP biogenesis | journal = Journal of Cell Science | volume = 117 | issue = Pt 19 | pages = 4423–33 | date = September 2004 | pmid = 15316075 | doi = 10.1242/jcs.01308 | url = https://archive-ouverte.unige.ch/unige:17542/ATTACHMENT01 }} | ||
{{refend}} | {{refend}} | ||
{{gene-19-stub}} | {{gene-19-stub}} | ||
Latest revision as of 01:19, 28 November 2018
| VALUE_ERROR (nil) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Aliases | |||||||
| External IDs | GeneCards: [1] | ||||||
| Orthologs | |||||||
| Species | Human | Mouse | |||||
| Entrez |
|
| |||||
| Ensembl |
|
| |||||
| UniProt |
|
| |||||
| RefSeq (mRNA) |
|
| |||||
| RefSeq (protein) |
|
| |||||
| Location (UCSC) | n/a | n/a | |||||
| PubMed search | n/a | n/a | |||||
| Wikidata | |||||||
| |||||||
Splicing factor 3A subunit 2 is a protein that in humans is encoded by the SF3A2 gene.[1][2][3]
Function
This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.[3]
Interactions
SF3A2 has been shown to interact with DDX46.[4]
References
- ↑ Bennett M, Reed R (October 1993). "Correspondence between a mammalian spliceosome component and an essential yeast splicing factor". Science. 262 (5130): 105–8. doi:10.1126/science.8211113. PMID 8211113.
- ↑ Dresser DW, Hacker A, Lovell-Badge R, Guerrier D (September 1995). "The genes for a spliceosome protein (SAP62) and the anti-Müllerian hormone (AMH) are contiguous". Human Molecular Genetics. 4 (9): 1613–8. doi:10.1093/hmg/4.9.1613. PMID 8541848.
- ↑ 3.0 3.1 "Entrez Gene: SF3A2 splicing factor 3a, subunit 2, 66kDa".
- ↑ Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Lührmann R (September 2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". The EMBO Journal. 21 (18): 4978–88. doi:10.1093/emboj/cdf480. PMC 126279. PMID 12234937.
Further reading
- Chiara MD, Champion-Arnaud P, Buvoli M, Nadal-Ginard B, Reed R (July 1994). "Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114". Proceedings of the National Academy of Sciences of the United States of America. 91 (14): 6403–7. doi:10.1073/pnas.91.14.6403. PMC 44210. PMID 8022796.
- Rain JC, Tartakoff AM, Krämer A, Legrain P (June 1996). "Essential domains of the PRP21 splicing factor are implicated in the binding to PRP9 and PRP11 proteins and are conserved through evolution". RNA. 2 (6): 535–50. PMC 1369393. PMID 8718683.
- Hong W, Bennett M, Xiao Y, Feld Kramer R, Wang C, Reed R (January 1997). "Association of U2 snRNP with the spliceosomal complex E". Nucleic Acids Research. 25 (2): 354–61. doi:10.1093/nar/25.2.354. PMC 146436. PMID 9016565.
- Moraitou M, Patrinou-Georgoula M, Guialis A (May 1998). "Structural/functional properties of a mammalian multi-component structure containing all major spliceosomal small nuclear ribonucleoprotein particles". The Biochemical Journal. 332 ( Pt 1) (1): 135–44. PMC 1219461. PMID 9576861.
- Yan D, Perriman R, Igel H, Howe KJ, Neville M, Ares M (September 1998). "CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif". Molecular and Cellular Biology. 18 (9): 5000–9. PMC 109085. PMID 9710584.
- Neubauer G, King A, Rappsilber J, Calvio C, Watson M, Ajuh P, Sleeman J, Lamond A, Mann M (September 1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex". Nature Genetics. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.
- Krämer A, Grüter P, Gröning K, Kastner B (June 1999). "Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP". The Journal of Cell Biology. 145 (7): 1355–68. doi:10.1083/jcb.145.7.1355. PMC 2133165. PMID 10385517.
- Das R, Zhou Z, Reed R (May 2000). "Functional association of U2 snRNP with the ATP-independent spliceosomal complex E". Molecular Cell. 5 (5): 779–87. doi:10.1016/S1097-2765(00)80318-4. PMID 10882114.
- Will CL, Schneider C, MacMillan AM, Katopodis NF, Neubauer G, Wilm M, Lührmann R, Query CC (August 2001). "A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site". The EMBO Journal. 20 (16): 4536–46. doi:10.1093/emboj/20.16.4536. PMC 125580. PMID 11500380.
- Nesic D, Krämer A (October 2001). "Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation". Molecular and Cellular Biology. 21 (19): 6406–17. doi:10.1128/MCB.21.19.6406-6417.2001. PMC 99788. PMID 11533230.
- Dresser DW, Jamin SP, Atkins CJ, Guerrier D (October 2001). "An expressed GNRP-like gene shares a bi-directional promoter with SF3A2 (SAP62) immediately upstream of AMH". Gene. 277 (1–2): 163–73. doi:10.1016/S0378-1119(01)00690-4. PMID 11602354.
- Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ (April 2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
- Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Lührmann R (September 2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". The EMBO Journal. 21 (18): 4978–88. doi:10.1093/emboj/cdf480. PMC 126279. PMID 12234937.
- Takenaka K, Nakagawa H, Miyamoto S, Miki H (August 2004). "The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein". The Biochemical Journal. 382 (Pt 1): 223–30. doi:10.1042/BJ20040521. PMC 1133934. PMID 15142036.
- Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (July 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
- Nesic D, Tanackovic G, Krämer A (September 2004). "A role for Cajal bodies in the final steps of U2 snRNP biogenesis". Journal of Cell Science. 117 (Pt 19): 4423–33. doi:10.1242/jcs.01308. PMID 15316075.
 | This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it. |