EPS15L1: Difference between revisions

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Latest revision as of 13:14, 7 November 2018

Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1 gene.^[1]

Interactions

EPS15L1 has been shown to interact with HRB.^[2]

References

↑ "Entrez Gene: EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1".
↑ Doria M, Salcini AE, Colombo E, Parslow TG, Pelicci PG, Di Fiore PP (Dec 1999). "The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport". J. Cell Biol. 147 (7): 1379–84. doi:10.1083/jcb.147.7.1379. PMC 2174238. PMID 10613896.

Salcini AE, Confalonieri S, Doria M, Santolini E, Tassi E, Minenkova O, Cesareni G, Pelicci PG, Di Fiore PP (1997). "Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module". Genes Dev. 11 (17): 2239–49. doi:10.1101/gad.11.17.2239. PMC 275390. PMID 9303539.
Carbone R, Fré S, Iannolo G, Belleudi F, Mancini P, Pelicci PG, Torrisi MR, Di Fiore PP (1997). "eps15 and eps15R are essential components of the endocytic pathway". Cancer Res. 57 (24): 5498–504. PMID 9407958.
Coda L, Salcini AE, Confalonieri S, Pelicci G, Sorkina T, Sorkin A, Pelicci PG, Di Fiore PP (1998). "Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization". J. Biol. Chem. 273 (5): 3003–12. doi:10.1074/jbc.273.5.3003. PMID 9446614.
Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis". Nature. 394 (6695): 793–7. doi:10.1038/29555. PMID 9723620.
Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M (1998). "Selection system for genes encoding nuclear-targeted proteins". Nat. Biotechnol. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615.
Doria M, Salcini AE, Colombo E, Parslow TG, Pelicci PG, Di Fiore PP (1999). "The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport". J. Cell Biol. 147 (7): 1379–84. doi:10.1083/jcb.147.7.1379. PMC 2174238. PMID 10613896.
Offenhäuser N, Santolini E, Simeone A, Di Fiore PP (2000). "Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis". Mech. Dev. 95 (1–2): 309–12. doi:10.1016/S0925-4773(00)00363-4. PMID 10906484.
Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS (2001). "Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery". J. Cell Biol. 153 (5): 1111–20. doi:10.1083/jcb.153.5.1111. PMC 2174325. PMID 11381094.
Poupon V, Polo S, Vecchi M, Martin G, Dautry-Varsat A, Cerf-Bensussan N, Di Fiore PP, Benmerah A (2002). "Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R". J. Biol. Chem. 277 (11): 8941–8. doi:10.1074/jbc.M108385200. PMID 11777906.
Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Schmid EM, Ford MG, Burtey A, Praefcke GJ, Peak-Chew SY, Mills IG, Benmerah A, McMahon HT (2006). "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly". PLoS Biol. 4 (9): e262. doi:10.1371/journal.pbio.0040262. PMC 1540706. PMID 16903783.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1".

[pmid10613896-2] Doria M, Salcini AE, Colombo E, Parslow TG, Pelicci PG, Di Fiore PP (Dec 1999). "The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport". J. Cell Biol. 147 (7): 1379–84. doi:10.1083/jcb.147.7.1379. PMC 2174238. PMID 10613896.

[1]

[2]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Epidermal growth factor receptor substrate 15-like 1''' is a [[protein]] that in humans is encoded by the ''EPS15L1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=58513| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Epidermal growth factor receptor pathway substrate 15-like 1
- | HGNCid = 24634
- | Symbol = EPS15L1
- | AltSymbols =; EPS15R
- | OMIM =
- | ECnumber =
- | Homologene = 31881
- | MGIid = 104582
- | GeneAtlas_image1 = PBB_GE_EPS15L1_222113_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_EPS15L1_221056_x_at_tn.png
- | GeneAtlas_image3 = PBB_GE_EPS15L1_222112_at_tn.png
- | Function = {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005905 |text = coated pit}}
- | Process = {{GNF_GO|id=GO:0006897 |text = endocytosis}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 58513
-    | Hs_Ensembl = ENSG00000127527
-    | Hs_RefseqProtein = NP_067058
-    | Hs_RefseqmRNA = NM_021235
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 19
-    | Hs_GenLoc_start = 16333408
-    | Hs_GenLoc_end = 16443762
-    | Hs_Uniprot = Q9UBC2
-    | Mm_EntrezGene = 13859
-    | Mm_Ensembl = ENSMUSG00000006276
-    | Mm_RefseqmRNA = NM_007944
-    | Mm_RefseqProtein = NP_031970
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 8
-    | Mm_GenLoc_start = 75270370
-    | Mm_GenLoc_end = 75329222
-    | Mm_Uniprot = Q3UIS9
-  }}
-}}
-'''Epidermal growth factor receptor pathway substrate 15-like 1''', also known as '''EPS15L1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=58513| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+EPS15L1 has been shown to [[Protein-protein interaction|interact]] with [[HRB (gene)|HRB]].<ref name=pmid10613896>{{cite journal | vauthors = Doria M, Salcini AE, Colombo E, Parslow TG, Pelicci PG, Di Fiore PP | title = The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport | journal = J. Cell Biol. | volume = 147 | issue = 7 | pages = 1379–84  | date = Dec 1999 | pmid = 10613896 | pmc = 2174238 | doi = 10.1083/jcb.147.7.1379 }}</ref>
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Salcini AE, Confalonieri S, Doria M, Santolini E, Tassi E, Minenkova O, Cesareni G, Pelicci PG, Di Fiore PP | title = Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module | journal = Genes Dev. | volume = 11 | issue = 17 | pages = 2239–49 | year = 1997 | pmid = 9303539 | pmc = 275390 | doi = 10.1101/gad.11.17.2239 }}
-| citations =
+* {{cite journal | vauthors = Carbone R, Fré S, Iannolo G, Belleudi F, Mancini P, Pelicci PG, Torrisi MR, Di Fiore PP | title = eps15 and eps15R are essential components of the endocytic pathway | journal = Cancer Res. | volume = 57 | issue = 24 | pages = 5498–504 | year = 1997 | pmid = 9407958 | doi =  }}
-*{{cite journal  | author=Salcini AE, Confalonieri S, Doria M, ''et al.'' |title=Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. |journal=Genes Dev. |volume=11 |issue= 17 |pages= 2239-49 |year= 1997 |pmid= 9303539 |doi=  }}
+* {{cite journal | vauthors = Coda L, Salcini AE, Confalonieri S, Pelicci G, Sorkina T, Sorkin A, Pelicci PG, Di Fiore PP | title = Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization | journal = J. Biol. Chem. | volume = 273 | issue = 5 | pages = 3003–12 | year = 1998 | pmid = 9446614 | doi = 10.1074/jbc.273.5.3003 }}
-*{{cite journal  | author=Carbone R, Fré S, Iannolo G, ''et al.'' |title=eps15 and eps15R are essential components of the endocytic pathway. |journal=Cancer Res. |volume=57 |issue= 24 |pages= 5498-504 |year= 1998 |pmid= 9407958 |doi=  }}
+* {{cite journal | vauthors = Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P | title = Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis | journal = Nature | volume = 394 | issue = 6695 | pages = 793–7 | year = 1998 | pmid = 9723620 | doi = 10.1038/29555 }}
-*{{cite journal  | author=Coda L, Salcini AE, Confalonieri S, ''et al.'' |title=Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization. |journal=J. Biol. Chem. |volume=273 |issue= 5 |pages= 3003-12 |year= 1998 |pmid= 9446614 |doi=  }}
+* {{cite journal | vauthors = Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M | title = Selection system for genes encoding nuclear-targeted proteins | journal = Nat. Biotechnol. | volume = 16 | issue = 13 | pages = 1338–42 | year = 1998 | pmid = 9853615 | doi = 10.1038/4315 }}
-*{{cite journal  | author=Chen H, Fre S, Slepnev VI, ''et al.'' |title=Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis. |journal=Nature |volume=394 |issue= 6695 |pages= 793-7 |year= 1998 |pmid= 9723620 |doi= 10.1038/29555 }}
+* {{cite journal | vauthors = Doria M, Salcini AE, Colombo E, Parslow TG, Pelicci PG, Di Fiore PP | title = The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport | journal = J. Cell Biol. | volume = 147 | issue = 7 | pages = 1379–84 | year = 1999 | pmid = 10613896 | pmc = 2174238 | doi = 10.1083/jcb.147.7.1379 }}
-*{{cite journal  | author=Ueki N, Oda T, Kondo M, ''et al.'' |title=Selection system for genes encoding nuclear-targeted proteins. |journal=Nat. Biotechnol. |volume=16 |issue= 13 |pages= 1338-42 |year= 1999 |pmid= 9853615 |doi= 10.1038/4315 }}
+* {{cite journal | vauthors = Offenhäuser N, Santolini E, Simeone A, Di Fiore PP | title = Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis | journal = Mech. Dev. | volume = 95 | issue = 1–2 | pages = 309–12 | year = 2000 | pmid = 10906484 | doi = 10.1016/S0925-4773(00)00363-4 }}
-*{{cite journal  | author=Doria M, Salcini AE, Colombo E, ''et al.'' |title=The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport. |journal=J. Cell Biol. |volume=147 |issue= 7 |pages= 1379-84 |year= 2000 |pmid= 10613896 |doi=  }}
+* {{cite journal | vauthors = Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS | title = Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery | journal = J. Cell Biol. | volume = 153 | issue = 5 | pages = 1111–20 | year = 2001 | pmid = 11381094 | pmc = 2174325 | doi = 10.1083/jcb.153.5.1111 }}
-*{{cite journal  | author=Offenhäuser N, Santolini E, Simeone A, Di Fiore PP |title=Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis. |journal=Mech. Dev. |volume=95 |issue= 1-2 |pages= 309-12 |year= 2000 |pmid= 10906484 |doi=  }}
+* {{cite journal | vauthors = Poupon V, Polo S, Vecchi M, Martin G, Dautry-Varsat A, Cerf-Bensussan N, Di Fiore PP, Benmerah A | title = Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R | journal = J. Biol. Chem. | volume = 277 | issue = 11 | pages = 8941–8 | year = 2002 | pmid = 11777906 | doi = 10.1074/jbc.M108385200 }}
-*{{cite journal  | author=Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS |title=Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery. |journal=J. Cell Biol. |volume=153 |issue= 5 |pages= 1111-20 |year= 2001 |pmid= 11381094 |doi=  }}
+* {{cite journal | vauthors = Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC | title = Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry | journal = Anal. Chem. | volume = 76 | issue = 10 | pages = 2763–72 | year = 2004 | pmid = 15144186 | doi = 10.1021/ac035352d }}
-*{{cite journal  | author=Poupon V, Polo S, Vecchi M, ''et al.'' |title=Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R. |journal=J. Biol. Chem. |volume=277 |issue= 11 |pages= 8941-8 |year= 2002 |pmid= 11777906 |doi= 10.1074/jbc.M108385200 }}
+* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 33 | pages = 12130–5 | year = 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+* {{cite journal | vauthors = Schmid EM, Ford MG, Burtey A, Praefcke GJ, Peak-Chew SY, Mills IG, Benmerah A, McMahon HT | title = Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly | journal = PLoS Biol. | volume = 4 | issue = 9 | pages = e262 | year = 2006 | pmid = 16903783 | pmc = 1540706 | doi = 10.1371/journal.pbio.0040262 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+* {{cite journal | vauthors = Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP | title = A probability-based approach for high-throughput protein phosphorylation analysis and site localization | journal = Nat. Biotechnol. | volume = 24 | issue = 10 | pages = 1285–92 | year = 2006 | pmid = 16964243 | doi = 10.1038/nbt1240 }}
-*{{cite journal  | author=Brill LM, Salomon AR, Ficarro SB, ''et al.'' |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763-72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d }}
+* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
-*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Schmid EM, Ford MG, Burtey A, ''et al.'' |title=Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly. |journal=PLoS Biol. |volume=4 |issue= 9 |pages= e262 |year= 2007 |pmid= 16903783 |doi= 10.1371/journal.pbio.0040262 }}
-*{{cite journal  | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
-}}
 {{refend}}
 {{gene-19-stub}}
-{{WikiDoc Sources}}
+[[Category:EF-hand-containing proteins]]

EPS15L1: Difference between revisions

Latest revision as of 13:14, 7 November 2018

Interactions

References

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