EPS8L1: Difference between revisions
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'''Epidermal growth factor receptor kinase substrate 8-like protein 1''' is an [[enzyme]] that in humans is encoded by the ''EPS8L1'' [[gene]].<ref name="pmid12620401">{{cite journal | vauthors = Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C | title = In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure | journal = Genomics | volume = 81 | issue = 2 | pages = 234–44 |date=Mar 2003 | pmid = 12620401 | pmc = | doi =10.1016/S0888-7543(03)00002-8 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPS8L1 EPS8-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54869| accessdate = }}</ref> | '''Epidermal growth factor receptor kinase substrate 8-like protein 1''' is an [[enzyme]] that in humans is encoded by the ''EPS8L1'' [[gene]].<ref name="pmid12620401">{{cite journal | vauthors = Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C | title = In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure | journal = Genomics | volume = 81 | issue = 2 | pages = 234–44 |date=Mar 2003 | pmid = 12620401 | pmc = | doi =10.1016/S0888-7543(03)00002-8 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPS8L1 EPS8-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54869| accessdate = }}</ref> | ||
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| summary_text = This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Several alternatively spliced transcript variants encoding different isoforms exist.<ref name="entrez" /> | | summary_text = This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 ([[EPS8]]), a substrate for the [[epidermal growth factor receptor]]. The function of this protein is unknown. Several alternatively spliced [[transcript variants]] encoding different [[isoforms]] exist.<ref name="entrez" /> | ||
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Latest revision as of 17:23, 21 February 2018
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Epidermal growth factor receptor kinase substrate 8-like protein 1 is an enzyme that in humans is encoded by the EPS8L1 gene.[1][2]
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Several alternatively spliced transcript variants encoding different isoforms exist.[2]
References
- ↑ Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (Mar 2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure". Genomics. 81 (2): 234–44. doi:10.1016/S0888-7543(03)00002-8. PMID 12620401.
- ↑ 2.0 2.1 "Entrez Gene: EPS8L1 EPS8-like 1".
Further reading
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Offenhäuser N, Borgonovo A, Disanza A, et al. (2004). "The eps8 Family of Proteins Links Growth Factor Stimulation to Actin Reorganization Generating Functional Redundancy in the Ras/Rac Pathway". Mol. Biol. Cell. 15 (1): 91–8. doi:10.1091/mbc.E03-06-0427. PMC 307530. PMID 14565974.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Wu K, Xu Z, Wang M, et al. (1999). "[Cloning and expression analyses of down-regulated cDNA C6-2A in human esophageal cancer]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 16 (5): 325–7. PMID 10514543.
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