MARCH2: Difference between revisions

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'''E3 ubiquitin-protein ligase MARCH2''' is an [[enzyme]] that in humans is encoded by the ''MARCH2'' [[gene]].<ref name="pmid11042152">{{cite journal |vauthors=Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Res | volume = 10 | issue = 10 | pages = 1546–60 |date=Nov 2000 | pmid = 11042152 | pmc = 310934 | doi =10.1101/gr.140200 }}</ref><ref name="pmid14722266">{{cite journal |vauthors=Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Fruh K | title = Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins | journal = J Virol | volume = 78 | issue = 3 | pages = 1109–20 |date=Jan 2004 | pmid = 14722266 | pmc = 321412 | doi =10.1128/JVI.78.3.1109-1120.2004 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51257| accessdate = }}</ref>
'''E3 ubiquitin-protein ligase MARCH2''' is an [[enzyme]] that in humans is encoded by the ''MARCH2'' [[gene]].<ref name="pmid11042152">{{cite journal | vauthors = Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Research | volume = 10 | issue = 10 | pages = 1546–60 | date = October 2000 | pmid = 11042152 | pmc = 310934 | doi = 10.1101/gr.140200 }}</ref><ref name="pmid14722266">{{cite journal | vauthors = Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K | title = Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins | journal = Journal of Virology | volume = 78 | issue = 3 | pages = 1109–20 | date = February 2004 | pmid = 14722266 | pmc = 321412 | doi = 10.1128/JVI.78.3.1109-1120.2004 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51257| access-date = }}</ref> It is a member of the MARCH family of E3 ligases, and plays an important role in the [[Protein turnover|turnover]] of [[membrane proteins]].<ref name="Zhang_2018">{{cite journal | vauthors = Zhang Y, Lu J, Liu X | title = MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation | journal = Virology | volume = 518 | issue =  | pages = 293–300 | date = May 2018 | pmid = 29573664 | doi = 10.1016/j.virol.2018.02.003 }}</ref>


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== References ==
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==References==
== Further reading ==
{{reflist}}
{{refbegin|32em}}
 
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = April 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
==Further reading==
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = April 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
{{refbegin | 2}}
* {{cite journal | vauthors = Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW | title = Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation | journal = Nature Biotechnology | volume = 22 | issue = 6 | pages = 707–16 | date = June 2004 | pmid = 15146197 | doi = 10.1038/nbt971 }}
{{PBB_Further_reading
* {{cite journal | vauthors = Nakamura N, Fukuda H, Kato A, Hirose S | title = MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking | journal = Molecular Biology of the Cell | volume = 16 | issue = 4 | pages = 1696–710 | date = April 2005 | pmid = 15689499 | pmc = 1073653 | doi = 10.1091/mbc.E04-03-0216 }}
| citations =
* {{cite journal | vauthors = Fukuda H, Nakamura N, Hirose S | title = MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II | journal = Journal of Biochemistry | volume = 139 | issue = 1 | pages = 137–45 | date = January 2006 | pmid = 16428329 | doi = 10.1093/jb/mvj012 }}
* {{cite journal   |vauthors=Andersson B, Wentland MA, Ricafrente JY, etal |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146  }}
* {{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
* {{cite journal  |vauthors=Brandenberger R, Wei H, Zhang S, etal |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971 }}
* {{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
* {{cite journal  |vauthors=Nakamura N, Fukuda H, Kato A, Hirose S |title=MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking. |journal=Mol. Biol. Cell |volume=16 |issue= 4 |pages= 1696–710 |year= 2005 |pmid= 15689499 |doi= 10.1091/mbc.E04-03-0216 | pmc=1073653 }}
* {{cite journal |vauthors=Fukuda H, Nakamura N, Hirose S |title=MARCH-III Is a novel component of endosomes with properties similar to those of MARCH-II. |journal=J. Biochem. |volume=139 |issue= 1 |pages= 137–45 |year= 2007 |pmid= 16428329 |doi= 10.1093/jb/mvj012 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 07:03, 18 May 2018

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

E3 ubiquitin-protein ligase MARCH2 is an enzyme that in humans is encoded by the MARCH2 gene.[1][2][3] It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins.[4]

References

  1. Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (October 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  2. Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K (February 2004). "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins". Journal of Virology. 78 (3): 1109–20. doi:10.1128/JVI.78.3.1109-1120.2004. PMC 321412. PMID 14722266.
  3. "Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2".
  4. Zhang Y, Lu J, Liu X (May 2018). "MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation". Virology. 518: 293–300. doi:10.1016/j.virol.2018.02.003. PMID 29573664.

Further reading