ZRANB2: Difference between revisions

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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Zinc finger Ran-binding domain-containing protein 2''' is a [[protein]] that in humans is encoded by the ''ZRANB2'' [[gene]].<ref name="pmid9931435">{{cite journal | vauthors = Nakano M, Yoshiura K, Oikawa M, Miyoshi O, Yamada K, Kondo S, Miwa N, Soeda E, Jinno Y, Fujii T, Niikawa N | title = Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene | journal = Gene | volume = 225 | issue = 1–2 | pages = 59–65 | date = February 1999 | pmid = 9931435 | pmc =  | doi = 10.1016/S0378-1119(98)00536-8 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ZRANB2 zinc finger, RAN-binding domain containing 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9406| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image = PBB_Protein_ZRANB2_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1n0z.
| PDB = {{PDB2|1n0z}}
| Name = Zinc finger, RAN-binding domain containing 2
| HGNCid = 13058
| Symbol = ZRANB2
| AltSymbols =; DKFZp686J1831; DKFZp686N09117; FLJ41119; ZIS; ZIS1; ZIS2; ZNF265
| OMIM = 604347
| ECnumber = 
| Homologene = 3984
| MGIid = 1858211
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9406
    | Hs_Ensembl = ENSG00000132485
    | Hs_RefseqProtein = NP_005446
    | Hs_RefseqmRNA = NM_005455
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 71301562
    | Hs_GenLoc_end = 71319568
    | Hs_Uniprot = O95218
    | Mm_EntrezGene = 53861
    | Mm_Ensembl = ENSMUSG00000028180
    | Mm_RefseqmRNA = NM_017381
    | Mm_RefseqProtein = NP_059077
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 157469680
    | Mm_GenLoc_end = 157483633
    | Mm_Uniprot = Q3TI29
  }}
}}
'''Zinc finger, RAN-binding domain containing 2''', also known as '''ZRANB2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZRANB2 zinc finger, RAN-binding domain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9406| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
ZRANB2 has been shown to [[Protein-protein interaction|interact]] with [[U2 small nuclear RNA auxiliary factor 1]]<ref name=pmid11448987>{{cite journal | vauthors = Adams DJ, van der Weyden L, Mayeda A, Stamm S, Morris BJ, Rasko JE | title = ZNF265--a novel spliceosomal protein able to induce alternative splicing | journal = J. Cell Biol. | volume = 154 | issue = 1 | pages = 25–32 | date = July 2001 | pmid = 11448987 | pmc = 2196870 | doi = 10.1083/jcb.200010059 }}</ref> and [[SNRP70]].<ref name=pmid11448987/>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{Reflist}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Nakano M, Yoshiura K, Oikawa M, ''et al.'' |title=Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene. |journal=Gene |volume=225 |issue= 1-2 |pages= 59-65 |year= 1999 |pmid= 9931435 |doi=  }}
*{{cite journal  | author=Adams DJ, van der Weyden L, Kovacic A, ''et al.'' |title=Chromosome localization and characterization of the mouse and human zinc finger protein 265 gene. |journal=Cytogenet. Cell Genet. |volume=88 |issue= 1-2 |pages= 68-73 |year= 2000 |pmid= 10773668 |doi=  }}
*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal  | author=Suzuki Y, Tsunoda T, Sese J, ''et al.'' |title=Identification and characterization of the potential promoter regions of 1031 kinds of human genes. |journal=Genome Res. |volume=11 |issue= 5 |pages= 677-84 |year= 2001 |pmid= 11337467 |doi= 10.1101/gr.164001 }}
*{{cite journal  | author=Adams DJ, van der Weyden L, Mayeda A, ''et al.'' |title=ZNF265--a novel spliceosomal protein able to induce alternative splicing. |journal=J. Cell Biol. |volume=154 |issue= 1 |pages= 25-32 |year= 2001 |pmid= 11448987 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Plambeck CA, Kwan AH, Adams DJ, ''et al.'' |title=The structure of the zinc finger domain from human splicing factor ZNF265 fold. |journal=J. Biol. Chem. |volume=278 |issue= 25 |pages= 22805-11 |year= 2003 |pmid= 12657633 |doi= 10.1074/jbc.M301896200 }}
*{{cite journal  | author=Li J, Hawkins IC, Harvey CD, ''et al.'' |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437-47 |year= 2003 |pmid= 14559993 |doi=  }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Mangs AH, Speirs HJ, Goy C, ''et al.'' |title=XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265. |journal=Nucleic Acids Res. |volume=34 |issue= 17 |pages= 4976-86 |year= 2006 |pmid= 16982639 |doi= 10.1093/nar/gkl660 }}
*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
{{refend}}


{{protein-stub}}
== Further reading ==
{{WikiDoc Sources}}
{{Refbegin | 2}}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–174 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–156 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
* {{cite journal | vauthors = Adams DJ, van der Weyden L, Kovacic A, Lovicu FJ, Copeland NG, Gilbert DJ, Jenkins NA, Ioannou PA, Morris BJ | title = Chromosome localization and characterization of the mouse and human zinc finger protein 265 gene | journal = Cytogenet. Cell Genet. | volume = 88 | issue = 1–2 | pages = 68–73 | year = 2000 | pmid = 10773668 | doi = 10.1159/000015487 }}
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Res. | volume = 11 | issue = 3 | pages = 422–435 | year = 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
* {{cite journal | vauthors = Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S | title = Identification and characterization of the potential promoter regions of 1031 kinds of human genes | journal = Genome Res. | volume = 11 | issue = 5 | pages = 677–84 | year = 2001 | pmid = 11337467 | pmc = 311086 | doi = 10.1101/gr.gr-1640r }}
* {{cite journal | vauthors = Adams DJ, van der Weyden L, Mayeda A, Stamm S, Morris BJ, Rasko JE | title = ZNF265--a novel spliceosomal protein able to induce alternative splicing | journal = J. Cell Biol. | volume = 154 | issue = 1 | pages = 25–32 | year = 2001 | pmid = 11448987 | pmc = 2196870 | doi = 10.1083/jcb.200010059 }}
* {{cite journal | vauthors = Plambeck CA, Kwan AH, Adams DJ, Westman BJ, van der Weyden L, Medcalf RL, Morris BJ, Mackay JP | title = The structure of the zinc finger domain from human splicing factor ZNF265 fold | journal = J. Biol. Chem. | volume = 278 | issue = 25 | pages = 22805–22811 | year = 2003 | pmid = 12657633 | doi = 10.1074/jbc.M301896200 }}
* {{cite journal | vauthors = Li J, Hawkins IC, Harvey CD, Jennings JL, Link AJ, Patton JG | title = Regulation of alternative splicing by SRrp86 and its interacting proteins | journal = Mol. Cell. Biol. | volume = 23 | issue = 21 | pages = 7437–7447 | year = 2003 | pmid = 14559993 | pmc = 207616 | doi = 10.1128/MCB.23.21.7437-7447.2003 }}
* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 101 | issue = 33 | pages = 12130–12135 | year = 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}
* {{cite journal | vauthors = Mangs AH, Speirs HJ, Goy C, Adams DJ, Markus MA, Morris BJ | title = XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265 | journal = Nucleic Acids Res. | volume = 34 | issue = 17 | pages = 4976–4986 | year = 2006 | pmid = 16982639 | pmc = 1635291 | doi = 10.1093/nar/gkl660 }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–648 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
* {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Mol. Syst. Biol. | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
{{Refend}}
 
== External links ==
* {{UCSC genome browser|ZRANB2}}
* {{UCSC gene details|ZRANB2}}
 
{{PDB Gallery|geneid=9406}}
 
 
{{Gene-1-stub}}

Latest revision as of 15:19, 18 March 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger Ran-binding domain-containing protein 2 is a protein that in humans is encoded by the ZRANB2 gene.[1][2]

Interactions

ZRANB2 has been shown to interact with U2 small nuclear RNA auxiliary factor 1[3] and SNRP70.[3]

References

  1. Nakano M, Yoshiura K, Oikawa M, Miyoshi O, Yamada K, Kondo S, Miwa N, Soeda E, Jinno Y, Fujii T, Niikawa N (February 1999). "Identification, characterization and mapping of the human ZIS (zinc-finger, splicing) gene". Gene. 225 (1–2): 59–65. doi:10.1016/S0378-1119(98)00536-8. PMID 9931435.
  2. "Entrez Gene: ZRANB2 zinc finger, RAN-binding domain containing 2".
  3. 3.0 3.1 Adams DJ, van der Weyden L, Mayeda A, Stamm S, Morris BJ, Rasko JE (July 2001). "ZNF265--a novel spliceosomal protein able to induce alternative splicing". J. Cell Biol. 154 (1): 25–32. doi:10.1083/jcb.200010059. PMC 2196870. PMID 11448987.

Further reading

External links