RBM5: Difference between revisions

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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{Infobox_gene}}
{{GNF_Protein_box
'''RNA-binding protein 5''' is a [[protein]] that in humans is encoded by the ''RBM5'' [[gene]].<ref name="pmid10352938">{{cite journal | vauthors = Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH | title = A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3 | journal = Eur J Hum Genet | volume = 7 | issue = 4 | pages = 478–86 |date=Aug 1999 | pmid = 10352938 | pmc =  | doi = 10.1038/sj.ejhg.5200334 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RBM5 RNA binding motif protein 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10181| accessdate = }}</ref>
| image = 
| image_source = 
| PDB =
| Name = RNA binding motif protein 5
| HGNCid = 9902
| Symbol = RBM5
| AltSymbols =; FLJ39876; G15; H37; LUCA15; RMB5
| OMIM = 606884
| ECnumber = 
| Homologene = 21177
| MGIid = 1933204
| GeneAtlas_image1 = PBB_GE_RBM5_201394_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_RBM5_201395_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006396 |text = RNA processing}} {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0045786 |text = negative regulation of progression through cell cycle}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 10181
    | Hs_Ensembl = ENSG00000003756
    | Hs_RefseqProtein = NP_005769
    | Hs_RefseqmRNA = NM_005778
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 50101372
    | Hs_GenLoc_end = 50131392
    | Hs_Uniprot = P52756
    | Mm_EntrezGene = 83486
    | Mm_Ensembl = ENSMUSG00000032580
    | Mm_RefseqmRNA = NM_148930
    | Mm_RefseqProtein = NP_683732
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 9
    | Mm_GenLoc_start = 107598474
    | Mm_GenLoc_end = 107629040
    | Mm_Uniprot = Q05CY7
  }}
}}
'''RNA binding motif protein 5''', also known as '''RBM5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RBM5 RNA binding motif protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10181| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Timmer T, Terpstra P, van den Berg A, ''et al.'' |title=A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3. |journal=Eur. J. Hum. Genet. |volume=7 |issue= 4 |pages= 478-86 |year= 1999 |pmid= 10352938 |doi= 10.1038/sj.ejhg.5200334 }}
*{{cite journal   |vauthors=Timmer T, Terpstra P, van den Berg A, etal |title=An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers. |journal=Genomics |volume=60 |issue= 2 |pages= 238–40 |year= 1999 |pmid= 10486216 |doi= 10.1006/geno.1999.5878 }}
*{{cite journal  | author=Timmer T, Terpstra P, van den Berg A, ''et al.'' |title=An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers. |journal=Genomics |volume=60 |issue= 2 |pages= 238-40 |year= 1999 |pmid= 10486216 |doi= 10.1006/geno.1999.5878 }}
*{{cite journal  | vauthors=Oh JJ, Grosshans DR, Wong SG, Slamon DJ |title=Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. |journal=Nucleic Acids Res. |volume=27 |issue= 20 |pages= 4008–17 |year= 1999 |pmid= 10497265 |doi= 10.1093/nar/27.20.4008| pmc=148668 }}
*{{cite journal  | author=Oh JJ, Grosshans DR, Wong SG, Slamon DJ |title=Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. |journal=Nucleic Acids Res. |volume=27 |issue= 20 |pages= 4008-17 |year= 1999 |pmid= 10497265 |doi=  }}
*{{cite journal   |vauthors=Scanlan MJ, Gordan JD, Williamson B, etal |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma. |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456–64 |year= 1999 |pmid= 10508479 |doi=10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 }}
*{{cite journal | author=Scanlan MJ, Gordan JD, Williamson B, ''et al.'' |title=Antigens recognized by autologous antibody in patients with renal-cell carcinoma. |journal=Int. J. Cancer |volume=83 |issue= 4 |pages= 456-64 |year= 1999 |pmid= 10508479 |doi=  }}
*{{cite journal   |vauthors=Sutherland LC, Edwards SE, Cable HC, etal |title=LUCA-15-encoded sequence variants regulate CD95-mediated apoptosis. |journal=Oncogene |volume=19 |issue= 33 |pages= 3774–81 |year= 2000 |pmid= 10949932 |doi= 10.1038/sj.onc.1203720 }}
*{{cite journal | author=Sutherland LC, Edwards SE, Cable HC, ''et al.'' |title=LUCA-15-encoded sequence variants regulate CD95-mediated apoptosis. |journal=Oncogene |volume=19 |issue= 33 |pages= 3774-81 |year= 2000 |pmid= 10949932 |doi= 10.1038/sj.onc.1203720 }}
*{{cite journal  | vauthors=Oh JJ, West AR, Fishbein MC, Slamon DJ |title=A candidate tumor suppressor gene, H37, from the human lung cancer tumor suppressor locus 3p21.3. |journal=Cancer Res. |volume=62 |issue= 11 |pages= 3207–13 |year= 2002 |pmid= 12036935 |doi=  }}
*{{cite journal  | author=Oh JJ, West AR, Fishbein MC, Slamon DJ |title=A candidate tumor suppressor gene, H37, from the human lung cancer tumor suppressor locus 3p21.3. |journal=Cancer Res. |volume=62 |issue= 11 |pages= 3207-13 |year= 2002 |pmid= 12036935 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Mourtada-Maarabouni M, Sutherland LC, Meredith JM, Williams GT |title=Simultaneous acceleration of the cell cycle and suppression of apoptosis by splice variant delta-6 of the candidate tumour suppressor LUCA-15/RBM5. |journal=Genes Cells |volume=8 |issue= 2 |pages= 109–19 |year= 2003 |pmid= 12581154 |doi=10.1046/j.1365-2443.2003.00619.x }}
*{{cite journal  | author=Mourtada-Maarabouni M, Sutherland LC, Meredith JM, Williams GT |title=Simultaneous acceleration of the cell cycle and suppression of apoptosis by splice variant delta-6 of the candidate tumour suppressor LUCA-15/RBM5. |journal=Genes Cells |volume=8 |issue= 2 |pages= 109-19 |year= 2003 |pmid= 12581154 |doi=  }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | vauthors=Rintala-Maki ND, Sutherland LC |title=LUCA-15/RBM5, a putative tumour suppressor, enhances multiple receptor-initiated death signals. |journal=Apoptosis |volume=9 |issue= 4 |pages= 475–84 |year= 2005 |pmid= 15192330 |doi= 10.1023/B:APPT.0000031455.79352.57 }}
*{{cite journal  | author=Rintala-Maki ND, Sutherland LC |title=LUCA-15/RBM5, a putative tumour suppressor, enhances multiple receptor-initiated death signals. |journal=Apoptosis |volume=9 |issue= 4 |pages= 475-84 |year= 2005 |pmid= 15192330 |doi= 10.1023/B:APPT.0000031455.79352.57 }}
*{{cite journal  | vauthors=Rintala-Maki ND, Abrasonis V, Burd M, Sutherland LC |title=Genetic instability of RBM5/LUCA-15/H37 in MCF-7 breast carcinoma sublines may affect susceptibility to apoptosis. |journal=Cell Biochem. Funct. |volume=22 |issue= 5 |pages= 307–13 |year= 2005 |pmid= 15338470 |doi= 10.1002/cbf.1106 }}
*{{cite journal  | author=Rintala-Maki ND, Abrasonis V, Burd M, Sutherland LC |title=Genetic instability of RBM5/LUCA-15/H37 in MCF-7 breast carcinoma sublines may affect susceptibility to apoptosis. |journal=Cell Biochem. Funct. |volume=22 |issue= 5 |pages= 307-13 |year= 2005 |pmid= 15338470 |doi= 10.1002/cbf.1106 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Stelzl U, Worm U, Lalowski M, etal |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 }}
*{{cite journal | author=Stelzl U, Worm U, Lalowski M, ''et al.'' |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957-68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 }}
*{{cite journal   |vauthors=Mourtada-Maarabouni M, Keen J, Clark J, etal |title=Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes. |journal=Exp. Cell Res. |volume=312 |issue= 10 |pages= 1745–52 |year= 2006 |pmid= 16546166 |doi= 10.1016/j.yexcr.2006.02.009 }}
*{{cite journal | author=Mourtada-Maarabouni M, Keen J, Clark J, ''et al.'' |title=Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes. |journal=Exp. Cell Res. |volume=312 |issue= 10 |pages= 1745-52 |year= 2006 |pmid= 16546166 |doi= 10.1016/j.yexcr.2006.02.009 }}
*{{cite journal   |vauthors=Oh JJ, Razfar A, Delgado I, etal |title=3p21.3 tumor suppressor gene H37/Luca15/RBM5 inhibits growth of human lung cancer cells through cell cycle arrest and apoptosis. |journal=Cancer Res. |volume=66 |issue= 7 |pages= 3419–27 |year= 2006 |pmid= 16585163 |doi= 10.1158/0008-5472.CAN-05-1667 }}
*{{cite journal | author=Oh JJ, Razfar A, Delgado I, ''et al.'' |title=3p21.3 tumor suppressor gene H37/Luca15/RBM5 inhibits growth of human lung cancer cells through cell cycle arrest and apoptosis. |journal=Cancer Res. |volume=66 |issue= 7 |pages= 3419-27 |year= 2006 |pmid= 16585163 |doi= 10.1158/0008-5472.CAN-05-1667 }}
*{{cite journal   |vauthors=Masdeu C, Faure H, Coulombe J, etal |title=Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15. |journal=Biochem. Biophys. Res. Commun. |volume=349 |issue= 2 |pages= 471–9 |year= 2006 |pmid= 16945339 |doi= 10.1016/j.bbrc.2006.07.216 }}
*{{cite journal | author=Masdeu C, Faure H, Coulombe J, ''et al.'' |title=Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15. |journal=Biochem. Biophys. Res. Commun. |volume=349 |issue= 2 |pages= 471-9 |year= 2006 |pmid= 16945339 |doi= 10.1016/j.bbrc.2006.07.216 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
==External links==
{{WikiDoc Sources}}
* {{UCSC genome browser|RBM5}}
* {{UCSC gene details|RBM5}}
 
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{{gene-3-stub}}

Latest revision as of 15:57, 19 February 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

RNA-binding protein 5 is a protein that in humans is encoded by the RBM5 gene.[1][2]


References

  1. ↑ Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH (Aug 1999). "A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3". Eur J Hum Genet. 7 (4): 478–86. doi:10.1038/sj.ejhg.5200334. PMID 10352938.
  2. ↑ "Entrez Gene: RBM5 RNA binding motif protein 5".

Further reading

External links



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