Complement component 7: Difference between revisions
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{{infobox protein | {{infobox protein | ||
| Name = complement component 7 | | Name = complement component 7 | ||
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| LocusSupplementaryData = | | LocusSupplementaryData = | ||
}} | }} | ||
'''Complement component 7''' is a protein involved in the [[complement system]], | '''Complement component 7''' is a [[protein]] involved in the [[complement system]] of the [[innate immune system]]. C7 is part of the [[complement membrane attack complex|membrane attack complex (MAC)]] which creates a hole on [[pathogen]] surfaces, leading to cell [[lysis]] and death. | ||
Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the [[cell membrane|phospholipid bilayer]] of the pathogen. | |||
==See also== | |||
* [[Terminal complement pathway deficiency]] | |||
==External links== | ==External links== | ||
Latest revision as of 19:44, 4 January 2018
| complement component 7 | |
|---|---|
| Identifiers | |
| Symbol | C7 |
| Entrez | 730 |
| HUGO | 1346 |
| OMIM | 217070 |
| RefSeq | NM_000587 |
| UniProt | P10643 |
| Other data | |
| Locus | Chr. 5 p13 |
Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which creates a hole on pathogen surfaces, leading to cell lysis and death.
Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen.
See also
External links
- Complement+C7 at the US National Library of Medicine Medical Subject Headings (MeSH)
 | This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it. |