SLIT3: Difference between revisions

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{{Infobox_gene}}
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'''Slit homolog 3 protein''' is a [[protein]] that in humans is encoded by the ''SLIT3'' [[gene]].<ref name="pmid9693030">{{cite journal | vauthors = Nakayama M, Nakajima D, Nagase T, Nomura N, Seki N, Ohara O | title = Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening | journal = Genomics | volume = 51 | issue = 1 | pages = 27–34 | date = July 1998 | pmid = 9693030 | pmc =  | doi = 10.1006/geno.1998.5341 }}</ref><ref name="pmid9813312">{{cite journal | vauthors = Itoh A, Miyabayashi T, Ohno M, Sakano S | title = Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system | journal = Brain Research. Molecular Brain Research | volume = 62 | issue = 2 | pages = 175–86 | date = November 1998 | pmid = 9813312 | pmc =  | doi = 10.1016/S0169-328X(98)00224-1 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLIT3 slit homolog 3 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6586| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== References ==
{{GNF_Protein_box
{{reflist}}
| image = 
| image_source = 
| PDB =
| Name = Slit homolog 3 (Drosophila)
| HGNCid = 11087
| Symbol = SLIT3
| AltSymbols =; SLIT1; FLJ10764; MEGF5; SLIL2; Slit-3; slit2
| OMIM = 603745
| ECnumber = 
| Homologene = 2303
| MGIid = 1315202
| GeneAtlas_image1 = PBB_GE_SLIT3_203813_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005615 |text = extracellular space}}
| Process = {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007411 |text = axon guidance}} {{GNF_GO|id=GO:0007417 |text = central nervous system development}} {{GNF_GO|id=GO:0009887 |text = organ morphogenesis}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6586
    | Hs_Ensembl = ENSG00000184347
    | Hs_RefseqProtein = NP_003053
    | Hs_RefseqmRNA = NM_003062
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 168026037
    | Hs_GenLoc_end = 168660291
    | Hs_Uniprot = O75094
    | Mm_EntrezGene = 20564
    | Mm_Ensembl = ENSMUSG00000056427
    | Mm_RefseqmRNA = NM_011412
    | Mm_RefseqProtein = NP_035542
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 34964938
    | Mm_GenLoc_end = 35551565
    | Mm_Uniprot = Q3UHN1
  }}
}}
'''Slit homolog 3 (Drosophila)''', also known as '''SLIT3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLIT3 slit homolog 3 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6586| accessdate = }}</ref>


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== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Holmes GP, Negus K, Burridge L, Raman S, Algar E, Yamada T, Little MH | title = Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis | journal = Mechanisms of Development | volume = 79 | issue = 1-2 | pages = 57–72 | date = December 1998 | pmid = 10349621 | doi = 10.1016/S0925-4773(98)00174-9 }}
| citations =
* {{cite journal | vauthors = Little MH, Wilkinson L, Brown DL, Piper M, Yamada T, Stow JL | title = Dual trafficking of Slit3 to mitochondria and cell surface demonstrates novel localization for Slit protein | journal = American Journal of Physiology. Cell Physiology | volume = 281 | issue = 2 | pages = C486-95 | date = August 2001 | pmid = 11443047 | doi =  10.1152/ajpcell.2001.281.2.c486}}
*{{cite journal | author=Nakayama M, Nakajima D, Nagase T, ''et al.'' |title=Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening. |journal=Genomics |volume=51 |issue= 1 |pages= 27-34 |year= 1998 |pmid= 9693030 |doi= 10.1006/geno.1998.5341 }}
* {{cite journal | vauthors = Marillat V, Cases O, Nguyen-Ba-Charvet KT, Tessier-Lavigne M, Sotelo C, Chédotal A | title = Spatiotemporal expression patterns of slit and robo genes in the rat brain | journal = The Journal of Comparative Neurology | volume = 442 | issue = 2 | pages = 130–55 | date = January 2002 | pmid = 11754167 | doi = 10.1002/cne.10068 }}
*{{cite journal  | author=Itoh A, Miyabayashi T, Ohno M, Sakano S |title=Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system. |journal=Brain Res. Mol. Brain Res. |volume=62 |issue= 2 |pages= 175-86 |year= 1999 |pmid= 9813312 |doi=  }}
* {{cite journal | vauthors = Little M, Rumballe B, Georgas K, Yamada T, Teasdale RD | title = Conserved modularity and potential for alternate splicing in mouse and human Slit genes | journal = The International Journal of Developmental Biology | volume = 46 | issue = 4 | pages = 385–91 | year = 2003 | pmid = 12141424 | doi =  }}
*{{cite journal  | author=Holmes GP, Negus K, Burridge L, ''et al.'' |title=Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis. |journal=Mech. Dev. |volume=79 |issue= 1-2 |pages= 57-72 |year= 1999 |pmid= 10349621 |doi= }}
* {{cite journal | vauthors = Jiang LQ, Wen SJ, Wang HY, Chen LY | title = Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system | journal = Hypertension Research | volume = 25 | issue = 4 | pages = 647–52 | date = July 2002 | pmid = 12358155 | doi = 10.1291/hypres.25.647 }}
*{{cite journal | author=Little MH, Wilkinson L, Brown DL, ''et al.'' |title=Dual trafficking of Slit3 to mitochondria and cell surface demonstrates novel localization for Slit protein. |journal=Am. J. Physiol., Cell Physiol. |volume=281 |issue= 2 |pages= C486-95 |year= 2001 |pmid= 11443047 |doi=  }}
* {{cite journal | vauthors = Shi Y, Zhao X, Yu L, Tao R, Tang J, La Y, Duan Y, Gao B, Gu N, Xu Y, Feng G, Zhu S, Liu H, Salter H, He L | title = Genetic structure adds power to detect schizophrenia susceptibility at SLIT3 in the Chinese Han population | journal = Genome Research | volume = 14 | issue = 7 | pages = 1345–9 | date = July 2004 | pmid = 15231749 | pmc = 442150 | doi = 10.1101/gr.1758204 }}
*{{cite journal | author=Marillat V, Cases O, Nguyen-Ba-Charvet KT, ''et al.'' |title=Spatiotemporal expression patterns of slit and robo genes in the rat brain. |journal=J. Comp. Neurol. |volume=442 |issue= 2 |pages= 130-55 |year= 2002 |pmid= 11754167 |doi= }}
* {{cite journal | vauthors = Hammond R, Vivancos V, Naeem A, Chilton J, Mambetisaeva E, Mambitisaeva E, Andrews W, Sundaresan V, Guthrie S | title = Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain | journal = Development | volume = 132 | issue = 20 | pages = 4483–95 | date = October 2005 | pmid = 16162649 | doi = 10.1242/dev.02038 }}
*{{cite journal | author=Little M, Rumballe B, Georgas K, ''et al.'' |title=Conserved modularity and potential for alternate splicing in mouse and human Slit genes. |journal=Int. J. Dev. Biol. |volume=46 |issue= 4 |pages= 385-91 |year= 2003 |pmid= 12141424 |doi=  }}
* {{cite journal | vauthors = Lin L, Isacson O | title = Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits | journal = Stem Cells | volume = 24 | issue = 11 | pages = 2504–13 | date = November 2006 | pmid = 16840550 | pmc = 2613222 | doi = 10.1634/stemcells.2006-0119 }}
*{{cite journal | author=Jiang LQ, Wen SJ, Wang HY, Chen LY |title=Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system. |journal=Hypertens. Res. |volume=25 |issue= 4 |pages= 647-52 |year= 2003 |pmid= 12358155 |doi=  }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal | author=Clark HF, Gurney AL, Abaya E, ''et al.'' |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265-70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Shi Y, Zhao X, Yu L, ''et al.'' |title=Genetic structure adds power to detect schizophrenia susceptibility at SLIT3 in the Chinese Han population. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1345-9 |year= 2004 |pmid= 15231749 |doi= 10.1101/gr.1758204 }}
*{{cite journal | author=Hammond R, Vivancos V, Naeem A, ''et al.'' |title=Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain. |journal=Development |volume=132 |issue= 20 |pages= 4483-95 |year= 2005 |pmid= 16162649 |doi= 10.1242/dev.02038 }}
*{{cite journal | author=Lin L, Isacson O |title=Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits. |journal=Stem Cells |volume=24 |issue= 11 |pages= 2504-13 |year= 2006 |pmid= 16840550 |doi= 10.1634/stemcells.2006-0119 }}
}}
{{refend}}
{{refend}}


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{{WikiDoc Sources}}
 
[[Category:Slit proteins]]

Latest revision as of 18:21, 4 February 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Slit homolog 3 protein is a protein that in humans is encoded by the SLIT3 gene.[1][2][3]

References

  1. Nakayama M, Nakajima D, Nagase T, Nomura N, Seki N, Ohara O (July 1998). "Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening". Genomics. 51 (1): 27–34. doi:10.1006/geno.1998.5341. PMID 9693030.
  2. Itoh A, Miyabayashi T, Ohno M, Sakano S (November 1998). "Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system". Brain Research. Molecular Brain Research. 62 (2): 175–86. doi:10.1016/S0169-328X(98)00224-1. PMID 9813312.
  3. "Entrez Gene: SLIT3 slit homolog 3 (Drosophila)".

Further reading