CLDN12: Difference between revisions

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Identifiers
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Orthologs
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Latest revision as of 12:23, 4 November 2018

Claudin-12 is a protein that in humans is encoded by the CLDN12 gene.^[1] It belongs to the group of claudins.

References

↑ "Entrez Gene: CLDN12 claudin 12".

External links

Human CLDN12 genome location and CLDN12 gene details page in the UCSC Genome Browser.

Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport". Traffic. 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Niimi T, Nagashima K, Ward JM, et al. (2001). "claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing". Mol. Cell. Biol. 21 (21): 7380–90. doi:10.1128/MCB.21.21.7380-7390.2001. PMC 99911. PMID 11585919.
Kiuchi-Saishin Y, Gotoh S, Furuse M, et al. (2002). "Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments". J. Am. Soc. Nephrol. 13 (4): 875–86. PMID 11912246.
Brandner JM, Kief S, Grund C, et al. (2003). "Organization and formation of the tight junction system in human epidermis and cultured keratinocytes". Eur. J. Cell Biol. 81 (5): 253–63. doi:10.1078/0171-9335-00244. PMID 12067061.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Kitajiri SI, Furuse M, Morita K, et al. (2004). "Expression patterns of claudins, tight junction adhesion molecules, in the inner ear". Hear. Res. 187 (1–2): 25–34. doi:10.1016/S0378-5955(03)00338-1. PMID 14698084.
Acharya P, Beckel J, Ruiz WG, et al. (2004). "Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium". Am. J. Physiol. Renal Physiol. 287 (2): F305–18. doi:10.1152/ajprenal.00341.2003. PMID 15068973.
Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS (2015). "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res. doi:10.1021/acs.jproteome.5b00769. PMID 26680015.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: CLDN12 claudin 12".

[1]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Claudin-12''' is a [[protein]] that in humans is encoded by the ''CLDN12'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLDN12 claudin 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9069| accessdate = }}</ref> It belongs to the group of [[claudin]]s.
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Claudin 12
- | HGNCid = 2034
- | Symbol = CLDN12
- | AltSymbols =;
- | OMIM =
- | ECnumber =
- | Homologene = 40809
- | MGIid = 1929288
- | Function = {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0042802 |text = identical protein binding}}
- | Component = {{GNF_GO|id=GO:0005923 |text = tight junction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0016338 |text = calcium-independent cell-cell adhesion}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 9069
-    | Hs_Ensembl = ENSG00000157224
-    | Hs_RefseqProtein = NP_036261
-    | Hs_RefseqmRNA = NM_012129
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 7
-    | Hs_GenLoc_start = 89870698
-    | Hs_GenLoc_end = 89883200
-    | Hs_Uniprot = P56749
-    | Mm_EntrezGene = 64945
-    | Mm_Ensembl = ENSMUSG00000046798
-    | Mm_RefseqmRNA = NM_022890
-    | Mm_RefseqProtein = NP_075028
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 5
-    | Mm_GenLoc_start = 5511115
-    | Mm_GenLoc_end = 5520879
-    | Mm_Uniprot = Q9ET43
-  }}
-}}
-'''Claudin 12''', also known as '''CLDN12''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLDN12 claudin 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9069| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 54: / Line 9: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|CLDN12}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Kniesel U, Wolburg H |title=Tight junctions of the blood-brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57-76 |year= 2000 |pmid= 10690502 |doi=  }}
+*{{cite journal  | vauthors=Kniesel U, Wolburg H |title=Tight junctions of the blood–brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57–76 |year= 2000 |pmid= 10690502 |doi=10.1023/A:1006995910836  }}
-*{{cite journal  | author=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93-8 |year= 2001 |pmid= 11247307 |doi=  }}
+*{{cite journal  | vauthors=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93–8 |year= 2001 |pmid= 11247307 |doi=10.1034/j.1600-0854.2001.020203.x  }}
-*{{cite journal  | author=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285-93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088 }}
+*{{cite journal  | vauthors=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285–93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088 }}
-*{{cite journal  | author=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531-6 |year= 2003 |pmid= 12231346 |doi=  }}
+*{{cite journal  | vauthors=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531–6 |year= 2003 |pmid= 12231346 |doi=10.1016/S0955-0674(02)00362-9  }}
-*{{cite journal  | author=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1-44 |year= 2003 |pmid= 12475568 |doi=  }}
+*{{cite journal  | vauthors=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1–44 |year= 2003 |pmid= 12475568 |doi=10.1016/S0079-6107(02)00037-8  }}
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
+*{{cite journal  | vauthors=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=10.1101/gr.143000  | pmc=310948  }}
-*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
+*{{cite journal  | vauthors=Wiemann S, Weil B, Wellenreuther R |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 |display-authors=etal}}
-*{{cite journal  | author=Niimi T, Nagashima K, Ward JM, ''et al.'' |title=claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. |journal=Mol. Cell. Biol. |volume=21 |issue= 21 |pages= 7380-90 |year= 2001 |pmid= 11585919 |doi= 10.1128/MCB.21.21.7380-7390.2001 }}
+*{{cite journal  | vauthors=Niimi T, Nagashima K, Ward JM |title=claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing. |journal=Mol. Cell. Biol. |volume=21 |issue= 21 |pages= 7380–90 |year= 2001 |pmid= 11585919 |doi= 10.1128/MCB.21.21.7380-7390.2001  | pmc=99911 |display-authors=etal}}
-*{{cite journal  | author=Kiuchi-Saishin Y, Gotoh S, Furuse M, ''et al.'' |title=Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. |journal=J. Am. Soc. Nephrol. |volume=13 |issue= 4 |pages= 875-86 |year= 2002 |pmid= 11912246 |doi=  }}
+*{{cite journal  | vauthors=Kiuchi-Saishin Y, Gotoh S, Furuse M |title=Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. |journal=J. Am. Soc. Nephrol. |volume=13 |issue= 4 |pages= 875–86 |year= 2002 |pmid= 11912246 |doi=  |display-authors=etal}}
-*{{cite journal  | author=Brandner JM, Kief S, Grund C, ''et al.'' |title=Organization and formation of the tight junction system in human epidermis and cultured keratinocytes. |journal=Eur. J. Cell Biol. |volume=81 |issue= 5 |pages= 253-63 |year= 2003 |pmid= 12067061 |doi=  }}
+*{{cite journal  | vauthors=Brandner JM, Kief S, Grund C |title=Organization and formation of the tight junction system in human epidermis and cultured keratinocytes. |journal=Eur. J. Cell Biol. |volume=81 |issue= 5 |pages= 253–63 |year= 2003 |pmid= 12067061 |doi=10.1078/0171-9335-00244  |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
+*{{cite journal  | vauthors=Scherer SW, Cheung J, MacDonald JR |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205  | pmc=2882961 |doi= 10.1126/science.1083423 |display-authors=etal}}
-*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
+*{{cite journal  | vauthors=Hillier LW, Fulton RS, Fulton LA |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |display-authors=etal}}
-*{{cite journal  | author=Kitajiri SI, Furuse M, Morita K, ''et al.'' |title=Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. |journal=Hear. Res. |volume=187 |issue= 1-2 |pages= 25-34 |year= 2004 |pmid= 14698084 |doi=  }}
+*{{cite journal  | vauthors=Kitajiri SI, Furuse M, Morita K |title=Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. |journal=Hear. Res. |volume=187 |issue= 1–2 |pages= 25–34 |year= 2004 |pmid= 14698084 |doi=10.1016/S0378-5955(03)00338-1  |display-authors=etal}}
-*{{cite journal  | author=Acharya P, Beckel J, Ruiz WG, ''et al.'' |title=Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. |journal=Am. J. Physiol. Renal Physiol. |volume=287 |issue= 2 |pages= F305-18 |year= 2004 |pmid= 15068973 |doi= 10.1152/ajprenal.00341.2003 }}
+*{{cite journal  | vauthors=Acharya P, Beckel J, Ruiz WG |title=Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium. |journal=Am. J. Physiol. Renal Physiol. |volume=287 |issue= 2 |pages= F305–18 |year= 2004 |pmid= 15068973 |doi= 10.1152/ajprenal.00341.2003 |display-authors=etal}}
 }}
+* {{cite journal | vauthors = Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS | title = A systems proteomics view of the endogenous human claudin protein family | journal = J Proteome Res | date= 2015 | pmid = 26680015 | doi = 10.1021/acs.jproteome.5b00769 | url = https://archive-ouverte.unige.ch/unige:79118/ATTACHMENT01 }}
 {{refend}}
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CLDN12: Difference between revisions

Latest revision as of 12:23, 4 November 2018

References

External links

Further reading

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