Chondroma causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Chondroma}} | {{Chondroma}} | ||
{{CMG}}{{AE}} {{F.K}} {{STM}} | {{CMG}}; {{AE}} {{F.K}}, {{STM}} | ||
==Overview== | ==Overview== | ||
The cause of chondromas has not been identified | The cause of chondromas has not been identified. | ||
==Causes== | ==Causes== | ||
The cause of chondromas has not been identified. | * The cause of chondromas has not been identified. [[Fibroblast growth factor receptor]] (FGFR3) deletion may be induced multiple chondroma-like lesions, including [[Enchondroma|enchondromas]] and [[Osteochondroma|osteochondromas]].<ref name="pmid26091072">{{cite journal |vauthors=Zhou S, Xie Y, Tang J, Huang J, Huang Q, Xu W, Wang Z, Luo F, Wang Q, Chen H, Du X, Shen Y, Chen D, Chen L |title=FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling |journal=PLoS Genet. |volume=11 |issue=6 |pages=e1005214 |date=June 2015 |pmid=26091072 |pmc=4474636 |doi=10.1371/journal.pgen.1005214 |url=}}</ref> | ||
* However, enchondroma is believed to occur either as: | |||
** An overgrowth of the [[cartilage]] that lines the ends of the [[Bone|bones]] | |||
** A persistent growth of original [[embryonic]] [[cartilage]]. | |||
==References== | ==References== |
Latest revision as of 20:25, 24 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2], Soujanya Thummathati, MBBS [3]
Overview
The cause of chondromas has not been identified.
Causes
- The cause of chondromas has not been identified. Fibroblast growth factor receptor (FGFR3) deletion may be induced multiple chondroma-like lesions, including enchondromas and osteochondromas.[1]
- However, enchondroma is believed to occur either as:
References
- ↑ Zhou S, Xie Y, Tang J, Huang J, Huang Q, Xu W, Wang Z, Luo F, Wang Q, Chen H, Du X, Shen Y, Chen D, Chen L (June 2015). "FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling". PLoS Genet. 11 (6): e1005214. doi:10.1371/journal.pgen.1005214. PMC 4474636. PMID 26091072.