Diabetes insipidus Diagnostic study of choice: Difference between revisions
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{{Family tree | | | E01 | | | | E02 | | | | | | | | |E01= <br>• Plasma Na+ >143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm < Posm | E02= <br>• Plasma Na+ <143 mEq/L <br>• Posm <295 mOsm/kg H2O <br>• Uosm < Posm}} | {{Family tree | | | E01 | | | | E02 | | | | | | | | |E01= <br>• Plasma Na+ >143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm < Posm | E02= <br>• Plasma Na+ <143 mEq/L <br>• Posm <295 mOsm/kg H2O <br>• Uosm < Posm}} | ||
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{{Family tree | | | | | | | | | F01 | | | | | | | |F01= '''Water deprivation test''' (minimum for 7 hrs)<br>• Monitor body wt, Posm, Uosm, plasma AVP <br>• Inturrept and measure AVP/Copeptin if; <br>• >3-5% body wt loss <br>• Plasma Na+ > 143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm increases to normal }} | {{Family tree | | | |!| | | | | F01 | | | | | | | |F01= '''Water deprivation test''' (minimum for 7 hrs)<br>• Monitor body wt, Posm, Uosm, plasma AVP <br>• Inturrept and measure AVP/Copeptin if; <br>• >3-5% body wt loss <br>• Plasma Na+ > 143 mEq/L <br>• Posm >295 mOsm/kg H2O <br>• Uosm increases to normal }} | ||
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{{Family tree | | | |!| | G01 | | | | G02 | | | | | G01= Uosm < Posm| G02= Uosm > Posm }} | |||
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{{Family tree | | | |!| | |!| | H01 | | | | H02 | | H01= Partial DI| H02= Primary polydipsia }} | |||
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{{Family tree | | | | | | | | I01 | | | | | | | | | I01= '''Desmopressin challange test''' }} | |||
Latest revision as of 21:22, 24 January 2019
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Diabetes insipidus Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Diabetes insipidus Diagnostic study of choice On the Web |
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American Roentgen Ray Society Images of Diabetes insipidus Diagnostic study of choice |
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Risk calculators and risk factors for Diabetes insipidus Diagnostic study of choice |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]
Overview
Diagnostic Study of Choice
Diagnostic approach
| Clinical exam, signs, symptoms | |||||||||||||||||||||||||||||||||||||||
| 24-hrs water balance: •Confirm polyurea and polydipsia | |||||||||||||||||||||||||||||||||||||||
| 24-hrs urine volume: • >50-60 ml/kg (age 0-10) • >40-50 ml/kg (age >10) | |||||||||||||||||||||||||||||||||||||||
| Blood and urine test (Na+, Posm, Uosm) | Other diagnostic hypothesis | ||||||||||||||||||||||||||||||||||||||
• Plasma Na+ >143 mEq/L • Posm >295 mOsm/kg H2O • Uosm < Posm | • Plasma Na+ <143 mEq/L • Posm <295 mOsm/kg H2O • Uosm < Posm | ||||||||||||||||||||||||||||||||||||||
| Water deprivation test (minimum for 7 hrs) • Monitor body wt, Posm, Uosm, plasma AVP • Inturrept and measure AVP/Copeptin if; • >3-5% body wt loss • Plasma Na+ > 143 mEq/L • Posm >295 mOsm/kg H2O • Uosm increases to normal | |||||||||||||||||||||||||||||||||||||||
| Uosm < Posm | Uosm > Posm | ||||||||||||||||||||||||||||||||||||||
| Partial DI | Primary polydipsia | ||||||||||||||||||||||||||||||||||||||
| Desmopressin challange test | |||||||||||||||||||||||||||||||||||||||