Grb2 associated binding protein 3: Difference between revisions

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Latest revision as of 20:57, 13 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

GRB2 associated binding protein 3 is a protein that in humans is encoded by the GAB3 gene. [1]

Function

This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.

References

  1. ↑ "Entrez Gene: GRB2 associated binding protein 3". Retrieved 2016-07-26.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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