Paraganglioma history and symptoms: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(16 intermediate revisions by 4 users not shown)
Line 1: Line 1:
'''For patient information click [[Paraganglioma (patient information)|here]]'''
__NOTOC__
 
{{Paraganglioma}}
{{Paraganglioma}}
{{CMG}}


{{CMG}}; {{AE}}
==Overview==
==Overview==
A '''paraganglioma''' is a rare [[neoplasm]] that can be found in the abdomen, thorax, and in the head and neck region.  They are usually considered [[benign]] and complete surgical removal results in cure.  However, in about 3% of cases they are [[malignant]] and have the ability to [[metastasis|metastasize]].  Paragangliomas are still sometimes called '''glomus tumors''' (not to be confused with [[glomus tumor]]s of the skin) and '''chemodectomas''', but paraganglioma is the currently accepted and preferred term.
The majority of patients with [disease name] are asymptomatic.


Paragangliomas arise from the [[glomus cell]]s, which are special [[chemoreceptor]]s located along blood vessels that have a role in regulating blood pressure and blood flow.  The main concentration of glomus cells are found are in the [[carotid body]], located in the upper neck at the branching of the [[carotid artery|common carotid artery]], and the [[aortic body|aortic bodies]], located near the [[aorta|aortic arch]].  The glomus cells are a part of the paraganglion system composed of the extra-adrenal [[paraganglia]] of the [[autonomic nervous system]], derived from the embryonic [[neural crest]].  Thus, paragangliomas are a type of [[neuroendocrine tumor]], and are closely related to [[pheochromocytoma]]s.  Although all paragangliomas contain neurosecretory granules, only about 1-3% have clinical evidence of oversecretion.
OR
==History and symptoms==
Paragangliomas are described by their site of origin and are often given special names:


* '''Carotid paraganglioma''' ([[carotid body]] tumor): Is the most common of the head and neck paragangliomas. It usually presents as a painless neck mass, but larger tumors may cause cranial nerve palsies, usually of the [[vagus nerve]] and [[hypoglossal nerve]].
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].


* '''Glomus tympanicum''' and '''Glomus jugulare''': Both commonly present as a middle ear mass resulting in [[tinnitus]] (in 80%) and hearing loss (in 60%). The cranial nerves of the [[jugular foramen]] may be compressed, resulting swallowing difficulty. These patients present with a reddish bulge behind an intact ear drum.  This condition is also known as the "Red drum".  On application of pressure to the external ear canal with the help of a pneumatic ear speculum the mass could be seen to blanch.  This sign is known as "Brown's sign".
==History and Symptoms==
*The majority of patients with [disease name] are asymptomatic.
OR
*The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 
===History===
Patients with [disease name]] may have a positive history of:
*[History finding 1]
*[History finding 2]
*[History finding 3]


* '''Vagal paragangliomas''': These are the least common of the head and neck paragangliomas.  They usually present as a painless neck mass, but may result in [[dysphagia]] and hoarseness.
===Common Symptoms===
Common symptoms of [disease] include:
*[Symptom 1]
*[Symptom 2]
*[Symptom 3]


* '''Other sites''': Rare sites of involvement are the [[larynx]], nasal cavity, paranasal sinuses, [[thyroid]] gland, and the [[thoracic inlet]], as well as the bladder in extremely rare cases.
===Less Common Symptoms===
 
Less common symptoms of [disease name] include
*Difficulty swallowing (dysphagia)
*[Symptom 1]
*Dizziness
*[Symptom 2]
*Hearing problems or loss
*[Symptom 3]
*Hearing pulsations in the ear
*Hoarseness
*Pain
*Weakness or loss of movement in the face (facial nerve palsy)


==References==
==References==
{{reflist|2}}
{{Reflist|2}}
{{Epithelial neoplasms}}
 
[[de:Paragangliom]]
[[nl:Paraganglioom]]
[[sk:Paraganglióm]]
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}


[[Category:Disease]]
{{WH}}
[[Category:Types of cancer]]
{{WS}}
[[Category:Oncology]]
[[Category: (name of the system)]]
[[Category:Mature chapter]]

Latest revision as of 17:56, 31 January 2019

Paraganglioma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paraganglioma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT Scan

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Paraganglioma history and symptoms On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Paraganglioma history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Paraganglioma history and symptoms

CDC on Paraganglioma history and symptoms

Paraganglioma history and symptoms in the news

Blogs on Paraganglioma history and symptoms

Directions to Hospitals Treating Paraganglioma

Risk calculators and risk factors for Paraganglioma history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

  • The majority of patients with [disease name] are asymptomatic.

OR

  • The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  • Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 

History

Patients with [disease name]] may have a positive history of:

  • [History finding 1]
  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of [disease] include:

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

Less Common Symptoms

Less common symptoms of [disease name] include

  • [Symptom 1]
  • [Symptom 2]
  • [Symptom 3]

References

Template:WH Template:WS