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{{Appendix cancer}}
{{Appendix cancer}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{Soroush}}
==Overview==
==Overview==
There is no established system for the classification of [disease name].
[[Vermiform appendix|Appendix]] [[cancer]] is [[Classification|classifie]]<nowiki/>d according to the [[Histology|histological findings]]. According to [[World Health Organization|WHO]] classification, there are four major groups of appendix cancer including [[Epithelium|epithelial]] [[Tumor|tumors]], non-epithelial tumors, secondary tumors, and [[Hyperplasia|hyperplastic]] (metaplastic) [[polyp]]<nowiki/>s. [[Carcinoid Tumor|Carcinoid]] (well differentiated endocrine neoplasm), and [[adenocarcinoma]] are two major subtypes of [[Epithelial hyperplasia|epithelial tumors]], making the majority of [[Vermiform appendix|appendix]] [[cancer]] cases.
 
OR
 
[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
 
OR
 
[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
 
OR
 
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
 
OR
 
If the staging system involves specific and characteristic findings and features:
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
 
OR
 
The staging of [malignancy name] is based on the [staging system].
 
OR
 
There is no established system for the staging of [malignancy name].


==Classification==
==Classification==
 
*[[Vermiform appendix|Appendix]] [[cancer]] may be classified according to [[WHO]] classification into 4 groups:<ref name="WHO">Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019</ref>
There is no established system for the classification of [disease name].
:*[[Epithelial hyperplasia|Epithelial tumors]]
 
:*Non-epithelial tumors
OR
:*Secondary tumors
 
:*[[Metaplasticity|Hyperplastic (metaplastic) polyps]].
[Disease name] may be classified according to [classification method] into [number] subtypes/groups:  
*The table below summarizes the different types of appendix cancer according to the [[World Health Organization|WHO classification]].
*[Group1]
{| style="border: 5px; font-size: 90%; margin: 5px; width: 300px" align="center"
*[Group2]
! colspan="4" style="padding: 5px 5px; background: #4479BA; font-weight: bold; text-align:center;" |{{fontcolor|#FFF|'''WHO histological classification<br>Tumors of the appendix (Adapted from WHO/IARC)<ref name="WHO"> Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019</ref>'''}}
*[Group3]
|-
*[Group4]
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Epithelial tumors
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Non-epithelial tumors
OR
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Secondary tumors
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold; text-align:center;" | Hyperplastic polyp
[Disease name] may be classified into [large number > 6] subtypes based on:  
|-
*[Classification method 1]
| style="padding: 5px 5px; background: #F5F5F5; text-align:left;" |
*[Classification method 2]
*'''Adenoma'''
*[Classification method 3]
:*Tubular
 
:*Villous
[Disease name] may be classified into several subtypes based on:  
:*Tubulovillous
*[Classification method 1]
:*Serrated
*[Classification method 2]
*'''Carcinoma'''
*[Classification method 3]
:*Adenocarcinoma
 
:*Mucinous adenocarcinoma
OR
:*Signet-ring cell carcinoma
 
:*Small cell carcinoma
Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
:*Undifferentiated carcinoma
 
*'''Carcinoid (well differentiated endocrine neoplasm)'''
OR
:*EC-cell, serotonin-producing neoplasm
 
:*L-cell, glucagon-like peptide
'''If the staging system involves specific and characteristic findings and features:'''
:* and PP/PYY producing tumour
 
:*others
According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
*'''Tubular carcinoid '''
 
*'''Goblet cell carcinoid (mucinous carcinoid)'''
OR
*'''Mixed carcinoid-adenocarcinoma'''
 
*'''Others'''
The staging of [malignancy name] is based on the [staging system].
| style="padding: 5px 5px; background: #F5F5F5; text-align:left;" |
 
*'''Neuroma'''
OR
*'''Lipoma'''
 
*'''Leiomyoma'''
There is no established system for the staging of [malignancy name].
*'''Gastrointestinal stromal tumor'''
*'''Leiomyosarcoma'''
*'''Kaposi sarcoma'''
*'''Others'''
*'''Malignant lymphoma'''
| style="padding: 5px 5px; background: #F5F5F5; text-align:left;" |
| style="padding: 5px 5px; background: #F5F5F5; text-align:left;" |
|}


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
 
{{WS}}
[[Category:Surgery]]
[[Category: (name of the system)]]
[[Category:Medicine]]
[[Category:Emergency medicine]]
[[Category:Oncology]]
[[Category:Up-To-Date]]

Latest revision as of 18:11, 22 February 2019

Appendix cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Epidemiology and Demographics

Differentiating Appendix cancer from other Diseases

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

MRI

CT scan

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Appendix cancer classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Appendix cancer classification

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Appendix cancer classification

CDC on Appendix cancer classification

Appendix cancer classification in the news

Blogs on Appendix cancer classification

Directions to Hospitals Treating Appendix cancer

Risk calculators and risk factors for Appendix cancer classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

Appendix cancer is classified according to the histological findings. According to WHO classification, there are four major groups of appendix cancer including epithelial tumors, non-epithelial tumors, secondary tumors, and hyperplastic (metaplastic) polyps. Carcinoid (well differentiated endocrine neoplasm), and adenocarcinoma are two major subtypes of epithelial tumors, making the majority of appendix cancer cases.

Classification

  • The table below summarizes the different types of appendix cancer according to the WHO classification.
WHO histological classification
Tumors of the appendix (Adapted from WHO/IARC)[1]
Epithelial tumors Non-epithelial tumors Secondary tumors Hyperplastic polyp
  • Adenoma
  • Tubular
  • Villous
  • Tubulovillous
  • Serrated
  • Carcinoma
  • Adenocarcinoma
  • Mucinous adenocarcinoma
  • Signet-ring cell carcinoma
  • Small cell carcinoma
  • Undifferentiated carcinoma
  • Carcinoid (well differentiated endocrine neoplasm)
  • EC-cell, serotonin-producing neoplasm
  • L-cell, glucagon-like peptide
  • and PP/PYY producing tumour
  • others
  • Tubular carcinoid
  • Goblet cell carcinoid (mucinous carcinoid)
  • Mixed carcinoid-adenocarcinoma
  • Others
  • Neuroma
  • Lipoma
  • Leiomyoma
  • Gastrointestinal stromal tumor
  • Leiomyosarcoma
  • Kaposi sarcoma
  • Others
  • Malignant lymphoma

References

  1. ↑ 1.0 1.1 Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019
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