Thrombotic thrombocytopenic purpura screening: Difference between revisions
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{{ | {{Thrombotic thrombocytopenic purpura}} | ||
{{CMG}}; {{AE}} | {{CMG}}; {{AE}} {{S.G.}} | ||
==Overview== | ==Overview== | ||
There is insufficient evidence to recommend routine | There is no insufficient evidence to recommend routine [[Screening (medicine)|screening]] for TTP. | ||
==Screening== | ==Screening== | ||
There is no insufficient evidence to recommend routine screening for TTP. | * There is no insufficient [[evidence]] to recommend routine screening for TTP.<ref name="JolyCoppo2017">{{cite journal|last1=Joly|first1=Bérangère S.|last2=Coppo|first2=Paul|last3=Veyradier|first3=Agnès|title=Thrombotic thrombocytopenic purpura|journal=Blood|volume=129|issue=21|year=2017|pages=2836–2846|issn=0006-4971|doi=10.1182/blood-2016-10-709857}}</ref> | ||
* First test to be screening for [[ADAMTS13]] [[Activity (chemistry)|activity]]. [[ADAMTS13]] [[Activity (chemistry)|activity]] < 10%, TTP [[diagnosis]] is confirmed. | |||
* In sever [[deficiency]] of [[ADAMTS13]] second [[Screening (medicine)|screening]] is detection of anti-[[ADAMTS13]] [[Immunoglobulin G|IgG]] | |||
* [[Gene]] [[sequencing]] of [[ADAMTS13|A''DAMTS13'']] is a third test is used. | |||
*ADAMTS13 | |||
==References== | ==References== |
Latest revision as of 17:08, 25 February 2019
Thrombotic thrombocytopenic purpura Microchapters |
Differentiating Thrombotic thrombocytopenic purpura from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Thrombotic thrombocytopenic purpura screening On the Web |
American Roentgen Ray Society Images of Thrombotic thrombocytopenic purpura screening |
Directions to Hospitals Treating Thrombotic thrombocytopenic purpura |
Risk calculators and risk factors for Thrombotic thrombocytopenic purpura screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
There is no insufficient evidence to recommend routine screening for TTP.
Screening
- There is no insufficient evidence to recommend routine screening for TTP.[1]
- First test to be screening for ADAMTS13 activity. ADAMTS13 activity < 10%, TTP diagnosis is confirmed.
- In sever deficiency of ADAMTS13 second screening is detection of anti-ADAMTS13 IgG
- Gene sequencing of ADAMTS13 is a third test is used.
References
- ↑ Joly, Bérangère S.; Coppo, Paul; Veyradier, Agnès (2017). "Thrombotic thrombocytopenic purpura". Blood. 129 (21): 2836–2846. doi:10.1182/blood-2016-10-709857. ISSN 0006-4971.