Lymphangioma differential diagnosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{ | [[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Lymphangioma]] | ||
{{ | {{CMG}} {{AE}}{{Badria}} {{HL}} | ||
==Overview== | ==Overview== | ||
Lymphangioma must be differentiated from [[arteriovenous malformation]], [[branchial cleft]] [[cyst]], and [[dermoid cyst]]. | [[Lymphangioma]] must be differentiated from [[arteriovenous malformation]], [[branchial cleft]] [[cyst]], and [[dermoid cyst]]. | ||
==Differentiating Lymphangioma from other | ==Differentiating Lymphangioma from other diseases== | ||
Lymphangioma must be differentiated from [[ | [[Lymphangioma]] must be differentiated from following: | ||
* [[Arteriovenous malformation]] | |||
* [[Lymphangiosarcoma]] | |||
* [[Branchial cleft]] | |||
* [[Dermoid cyst]] | |||
* Other [[Vascular anomalies|vascular anomolies]] | |||
For more information on vascular anomolies [[Vascular anomalies|'''click here''']]. | |||
=== Classifying and differentiating vascular tumors === | |||
{{Family tree/start}} | |||
{{Family tree | | | | | | | A01 | | | | | | | |A01= '''[[Vascular malformations]]'''}} | |||
{{Family tree | |,|-|-|-|v|-|^|-|v|-|-|-|.| | |}} | |||
{{Family tree | B01 | | B02 | | B03 | | B04 | |B01='''''[[Simple vascular malformations]]'''''|B02='''''[[Combined vascular malformations]]'''''|B03='''''Vascular malformations of major named vessels'''''|B04='''''[[Vascular malformations asscoiated with other anomalies]]'''''}} | |||
{{Family tree | |!| | | |!| | | |!| | | |!| | |}} | |||
{{Family tree | |!| | | I02 | | I03 | | I04 | |I02=<table class="wikitable"> | |||
<tr><td>'''CM + VM'''</td><td>Capillary-venous malformation</td><td>CVM</td></tr> | |||
<tr><td>'''CM + LM'''</td><td>Capillary-lymphatic malformation</td><td>CLM</td></tr> | |||
<tr><td>'''CM + AVM'''</td><td>Capillary-arteriovenous malformation</td><td>CAVM</td></tr> | |||
<tr><td>'''LM + VM'''</td><td>Lymphatic-venous malformation</td><td>LVM</td></tr> | |||
<tr><td>'''CM + LM + VM'''</td><td>Capillary-lymphatic-venous malformation</td><td>CLVM</td></tr> | |||
<tr><td>'''CM + LM + AVM'''</td><td>Capillary-lymphatic-arteriovenous malformation</td><td>CLVM</td></tr> | |||
<tr><td>'''CM + VM + AVM'''</td><td>Capillary-venous-arteriovenous malformation</td><td>CVAVM</td></tr> | |||
<tr><td>'''CM + LM + VM + AVM'''</td><td>Capillary-lymphatic-venous-arteriovenous malformation</td><td>CLVAVM</td></tr> | |||
</table>|I03=<br>(also known as "channel type" or "truncal" vascular malformations)<br><table> | |||
<tr><td>'''Affect'''</td></tr> | |||
<tr><td>• Lymphatics<td></tr> | |||
<tr><td>• Veins</tr> | |||
<tr><td>• Arteries</tr> | |||
<tr><td>'''Anomalies of'''</td></tr> | |||
<tr><td>• Origin<td></tr> | |||
<tr><td>• Course<td></tr> | |||
<tr><td>• Number<td></tr> | |||
<tr><td>• Diameter (aplasia,<br>hypoplasia, stenosis,<br>ectasia / aneurysm)<td></tr> | |||
<tr><td>• Valves<td></tr> | |||
<tr><td>• Communication (AVF)<td></tr> | |||
<tr><td>• Persistence (of<br>embryonal vessel)<td></tr> | |||
</table>|I04=<table class="wikitable"> | |||
<tr><td>'''[[Klippel-Trenaunay syndrome]]'''</td><td>CM + VM +/-LM + limb overgrowth</td></tr> | |||
<tr><td>'''[[Parke's Weber syndrome]]'''</td><td>CM + AVF + limb overgrowth</td></tr> | |||
<tr><td>'''[[Servelle-Martorell syndrome]]'''</td><td>Limb VM + bone undergrowth</td></tr> | |||
<tr><td>'''[[Sturge-Weber syndrome]]'''</td><td>Facial + leptomeningeal CM + eye anomalies +/-bone and/or soft tissue overgrowth</td></tr> | |||
<tr><td>'''[[Maffucci syndrome]]'''</td><td>VM +/-spindle-cell hemangioma + enchondroma</td></tr> | |||
<tr><td>'''[[CLOVES syndrome]]'''</td><td>LM + VM + CM +/-AVM+ lipomatous overgrowth</td></tr> | |||
<tr><td>'''[[Proteus syndrome]]'''</td><td>CM, VM and/or LM + asymmetrical somatic overgrowth</td></tr> | |||
<tr><td>'''[[Bannayan-Riley-Ruvalcaba syndrome]]'''</td><td>lower lip CM + face and neck LM + asymmetry and partial/generalized overgrowth</td></tr> | |||
<tr><td colspan="2">'''Limb CM + congenital non-progressive limb overgrowth'''</td></tr> | |||
<tr><td colspan="2">'''Macrocephaly-CM (M-CM / MCAP)'''</td></tr> | |||
<tr><td colspan="2">'''Microcephaly-CM (MICCAP)'''</td></tr> | |||
</table>|}} | |||
{{Family tree | |!| | |}} | |||
{{Family tree | |!| | |}} | |||
{{Family tree | |)|-|-|-|v|-|-|-|v|-|-|-|v|-|-|-|.| | |}} | |||
{{Family tree | | C01 | | C02 | | C03 | | C04 | | C05 | |C01=[[Capillary malformations]] (CM)|C02=[[Lymphatic malformations]] (LM)|C03=[[Venous malformations]] (VM)|C04=[[Arteriovenous malformation]] (AVM)|C05=[[Arteriovenous fistula]]}} | |||
{{Family tree | |!| | | |!| | | |!| | | |!| | | |!| | | |}} | |||
{{Family tree | |)| D01 |)| E01 |)| F01 |)| G01 |)| H01 |D01=[[Nevus simplex]] / [[salmon patch]], “[[angel kiss]]”, “[[stork bite]]”|E01=<table> | |||
<tr><td>[[Common (cystic) LM]] </td></tr> | |||
<tr><td>• [[Macrocystic LM]]<td></tr> | |||
<tr><td>• [[Microcystic LM]]<td></tr> | |||
<tr><td>• [[Mixed cystic LM]]<td></tr> | |||
</table>|F01=[[Common VM]]|G01=Sporadic|H01=Sporadic}} | |||
{{Family tree | |!| | | |!| | | |!| | | |!| | | |!| | | |}} | |||
{{Family tree | |)| D02 |)| E02 |)| F02 |)| G02 |)| H02 |D02=<table> | |||
<tr><td>[[Cutaneous and/or mucosal CM]] (also known as [[“port-wine” stain]]) </td></tr> | |||
<tr><td>• [[Nonsyndromic CM]]<td></tr> | |||
<tr><td>• CM with CNS and/or ocular anomalies ([[Sturge-Weber syndrome]])<td></tr> | |||
<tr><td>• CM with bone and/or soft tissues overgrowth <td></tr> | |||
<tr><td>• [[Diffuse CM with overgrowth]] ([[DCMO]]) <td></tr> | |||
</table>|E02=[[Generalized lymphatic anomaly]] ([[GLA]])<br>[[Kaposiform lymphangiomatosis]] ([[KLA]])|F02=[[Familial VM cutaneo-mucosal]] ([[VMCM]])|G02=In [[HHT]]|H02=In [[HHT]]|}} | |||
{{Family tree | |!| | | |!| | | |!| | | |!| | | |!| | | |}} | |||
{{Family tree | |)| D03 |)| E03 |)| F03 |)| G03 |)| H03 |D03=<table> | |||
<tr><td>[[Reticulate CM]] </td></tr> | |||
<tr><td>• CM of MIC-CAP (microcephaly-capillary malformation)<td></tr> | |||
<tr><td>• CM of MCAP (megalencephaly-capillary malformation-polymicrogyria)<td></tr> | |||
</table> | |||
|E03=LM in [[Gorham-Stout disease]]|F03=[[Blue rubber bleb nevus (Bean) syndrome]] VM|G03=In [[CM-AVM]]|H03=In [[CM-AVM]]|}} | |||
{{Family tree | |!| | | |!| | | |!| | | |!| | | |!| | | | |}} | |||
{{Family tree | |)| D04 |)| E04 |)| F04 |`| G04 |`| H04 |D04=[[CM of CM-AVM]]|E04=Channel type LM|F04=[[Glomuvenous malformation]] ([[GVM]])|G04=Others|H04=Others|}} | |||
{{Family tree | |!| | | |!| | | |!| | | | | | | | | | | |}} | |||
{{Family tree | |)| D05 |)| E05 |)| F05 | | | | | | | | |D05=[[Cutis marmorata telangiectatica congenita]] ([[CMTC]])|E05=[[“Acquired” progressive lymphatic anomaly]] (so called [[acquired progressive "lymphangioma"]])|F05=[[Cerebral cavernous malformation]] ([[CCM]]) |}} | |||
{{Family tree | |!| | | |!| | | |!| | | | | | | | | | | |}} | |||
{{Family tree | |)| D06 |)| E06 |)| F06 | | | | | | | | |D06=Others|E06=[[Primary lymphedema]] |F06=[[Familial intraosseous vascular malformation]] ([[VMOS]])|}} | |||
{{Family tree | |!| | | |!| | | |!| | | | | | | | | | | |}} | |||
{{Family tree | |`| D07 |`| E07 |)| F07 | | | | | | | | |D07=<table> | |||
<tr><td>[[Telangiectasia]] </td></tr> | |||
<tr><td>• [[Hereditary hemorrhagic telangiectasia]] (HHT) <td></tr> | |||
<tr><td>• Others<td></tr> | |||
</table>|E07=Others|F07=[[Verrucous venous malformation]] (formerly [[verrucous hemangioma]])|}} | |||
{{Family tree | | | | | | | | | |!| | | | | | | | | | | |}} | |||
{{Family tree | | | | | | | | | |`| F08 | | | | | | | | |F08=Others|}} | |||
{{Family tree/end}} | |||
'''Abbreviations:''' CM:capillary malformation; VM:venous malformation; CVM:capillary venous malformation; LM:lymphatic malformation; CLM:capillary lymphatic malformation; AVM:arteriovenous malformation; CAVM:capillary arteriovenous malformation; LVM:lymphatic venous malformation; CLVM:capillary lymphatic venous malformation; CVAVM:capillary venous arteriovenous malformation; CLVAVM:capillary lymphatic venous arteriovenous malformation; AVF:arteriovenous fistula; CLOVES:congenital lipomatous overgrowth, vascular malformations, epidermal nevi, skeletal/scoliosis and spinal abnormalities; M-CM:macrocephaly-capillary malformation; MCAP:megalencephaly-capillary malformation-polymicrogyria; MICCAP:microcephaly-capillary malformation; CNS:central nervous system; DCMO:diffuse capillary malformation with overgrowth; CM-AVM:capillary malformation-arteriovenous malformation; CMTC:cutis marmorata telangiectatica congenita; HHT:hereditary hemorrhagic telangiectasia; GLA:generalized lymphatic anomaly; KLA:kaposiform lymphangiomatosis; VMCM:venous malformation cutaneo mucosal; GVM:glomuvenous malformation; CCM:cerebral cavernous malformation. | |||
'''Adapted from International Society for the Study of Vascular Anomalies'''<ref name="urlClassification | International Society for the Study of Vascular Anomalies">{{cite web |url=http://www.issva.org/classification |title=Classification | International Society for the Study of Vascular Anomalies |format= |work= |accessdate=}}</ref> | |||
==References== | ==References== | ||
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Latest revision as of 22:05, 27 February 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Badria Munir M.B.B.S.[2] Haytham Allaham, M.D. [3]
Overview
Lymphangioma must be differentiated from arteriovenous malformation, branchial cleft cyst, and dermoid cyst.
Differentiating Lymphangioma from other diseases
Lymphangioma must be differentiated from following:
For more information on vascular anomolies click here.
Classifying and differentiating vascular tumors
| Vascular malformations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Simple vascular malformations | Combined vascular malformations | Vascular malformations of major named vessels | Vascular malformations asscoiated with other anomalies | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| (also known as "channel type" or "truncal" vascular malformations)
|
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Capillary malformations (CM) | Lymphatic malformations (LM) | Venous malformations (VM) | Arteriovenous malformation (AVM) | Arteriovenous fistula | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Nevus simplex / salmon patch, “angel kiss”, “stork bite” |
| Common VM | Sporadic | Sporadic | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Generalized lymphatic anomaly (GLA) Kaposiform lymphangiomatosis (KLA) | Familial VM cutaneo-mucosal (VMCM) | In HHT | In HHT | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| LM in Gorham-Stout disease | Blue rubber bleb nevus (Bean) syndrome VM | In CM-AVM | In CM-AVM | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| CM of CM-AVM | Channel type LM | Glomuvenous malformation (GVM) | Others | Others | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cutis marmorata telangiectatica congenita (CMTC) | “Acquired” progressive lymphatic anomaly (so called acquired progressive "lymphangioma") | Cerebral cavernous malformation (CCM) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Others | Primary lymphedema | Familial intraosseous vascular malformation (VMOS) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Others | Verrucous venous malformation (formerly verrucous hemangioma) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Others | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abbreviations: CM:capillary malformation; VM:venous malformation; CVM:capillary venous malformation; LM:lymphatic malformation; CLM:capillary lymphatic malformation; AVM:arteriovenous malformation; CAVM:capillary arteriovenous malformation; LVM:lymphatic venous malformation; CLVM:capillary lymphatic venous malformation; CVAVM:capillary venous arteriovenous malformation; CLVAVM:capillary lymphatic venous arteriovenous malformation; AVF:arteriovenous fistula; CLOVES:congenital lipomatous overgrowth, vascular malformations, epidermal nevi, skeletal/scoliosis and spinal abnormalities; M-CM:macrocephaly-capillary malformation; MCAP:megalencephaly-capillary malformation-polymicrogyria; MICCAP:microcephaly-capillary malformation; CNS:central nervous system; DCMO:diffuse capillary malformation with overgrowth; CM-AVM:capillary malformation-arteriovenous malformation; CMTC:cutis marmorata telangiectatica congenita; HHT:hereditary hemorrhagic telangiectasia; GLA:generalized lymphatic anomaly; KLA:kaposiform lymphangiomatosis; VMCM:venous malformation cutaneo mucosal; GVM:glomuvenous malformation; CCM:cerebral cavernous malformation.
Adapted from International Society for the Study of Vascular Anomalies[1]