Desmoid tumor other diagnostic studies: Difference between revisions

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__NOTOC__
{{Desmoid tumor}}
{{CMG}} {{AE}}{{S.M.}}


==Overview==
Antibodies including smooth muscle actin, desmin and KIT are often examined to aid in distinguishing desmoids from other tumors.
==Other diagnostic studies==
{| class="wikitable"
|+Characteristic features of desmoid tumors on immunohistochemistry and relevant antibodies
!Other diagnostic tests
!Associated characteristics features
|-
|Immunohistochemistry
(aids histologic diagnosis)
|Spindle cells on immunohistochemical stains show the following features:
* Positive for: vimentin and smooth muscle actin and nuclear beta-catenin but are generally negative for desmin, cytokeratins, and S-100
*Regardless of the site, 90% of desmoids show nuclear reactivity (has relatively high specificity)
|-
|Antibodies
|In order to distinguish desmoid tumors from other tumors, following antibodies are often examined:
*Smooth muscle actin
*Desmin
*KIT
|}
==Reference==
{{Reflist|2}}
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Latest revision as of 16:29, 5 March 2019