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| __NOTOC__
| | #REDIRECT [[Breast cancer]] |
| {{SI}}
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| {{CMG}} {{AE}} {{MV}}
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| {{SK}} Cystosarcoma phyllodes;
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| ==Overview==
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| '''Phyllodes tumor''' (also known as ''cystosarcoma phyllodes''), is a typically large, fast-growing mass that arises from the periductal [[stromal cell]]s of the [[breast]]. Phyllodes tumors account for less than 1% of all breast [[Neoplasia|neoplasms]].
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| ==Historical Perspective==
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| *Phyllodes tumor was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
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| ==Classification==
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| *Phyllodes tumor may be classified according to [classification method] into [number] subtypes/groups:
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| :*[group1]
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| :*[group2]
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| :*[group3]
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| *Other variants of phyllodes tumor include [disease subtype 1], [disease subtype 2], and [disease subtype 3].
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| ==Pathophysiology==
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| *The pathogenesis of phyllodes tumor is characterized by [feature1], [feature2], and [feature3].
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| *Genes involved in the development of phyllodes tumor, include:
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| *On gross pathology, characteristic findings of phyllodes tumor, include:
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| :*Cleft/leaf-like structures
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| :*Friable mass
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| :*Well-defined margins
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| *On microscopic histopathological analysis,characteristic findings of phyllodes tumor, include:
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| :*Large slit-like spaces
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| :*Cellular myxoid stroma
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| :*+/-Infiltrative border
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| :*Stromal overgrowth
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| ==Causes==
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| * There are no established causes for phyllodes tumor.
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| ==Differentiating Phyllodes Tumor from Other Diseases==
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| *Phyllodes tumor must be differentiated from other diseases that cause a breast mass, such as:
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| :*[Differential dx1]
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| :*[Differential dx2]
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| :*[Differential dx3]
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| ==Epidemiology and Demographics==
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| * The prevalence of phyllodes tumor is approximately [number or range] per 100,000 individuals worldwide.
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| * In [year], the incidence of phyllodes tumor was estimated to be [number or range] cases per 100,000 individuals in [location].
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| ===Age===
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| *Patients of all age groups may develop phyllodes tumor.
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| ===Gender===
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| *Females are more commonly affected with phyllodes tumor than males.
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| ===Race===
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| *There is no racial predilection for phyllodes tumor.
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| ==Risk Factors==
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| *Common risk factors in the development of phyllodes tumor, include:
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| == Natural History, Complications and Prognosis==
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| *The majority of patients with phyllodes tumor remain asymptomatic for years.
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| *Early clinical features include palpable mass, mastalgia, and
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| *If left untreated, patients with phyllodes tumor may progress to develop metastases.
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| *Common complications of phyllodes tumor, include:
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| *Prognosis is generally poor, and the 5 year survival rate of patients with phyllodes tumor is approximately
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| == Diagnosis ==
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| ===Diagnostic Criteria===
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| *The diagnosis of phyllodes tumor is made with biopsy.
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| === Symptoms ===
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| *Phyllodes tumor is usually asymptomatic.
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| *Symptoms of phyllodes tumor may include the following:
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| :*[symptom 1]
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| :*[symptom 2]
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| :*[symptom 3]
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| :*[symptom 4]
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| :*[symptom 5]
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| :*[symptom 6]
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| === Physical Examination ===
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| *Patients with phyllodes tumor usually appear [general appearance].
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| *Physical examination may be remarkable for:
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| :*[finding 1]
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| :*[finding 2]
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| :*[finding 3]
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| :*[finding 4]
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| :*[finding 5]
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| :*[finding 6]
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| === Laboratory Findings ===
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| *There are no specific laboratory findings associated with phyllodes tumor.
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| *A [positive/negative] [test name] is diagnostic of phyllodes tumor.
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| *An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of phyllodes tumor.
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| *Other laboratory findings consistent with the diagnosis of phyllodes tumor include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
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| ===Imaging Findings===
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| *[Imaging study 1] is the imaging modality of choice for phyllodes tumor.
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| *On [imaging study 1], findings of phyllodes tumor include:
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| == Treatment ==
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| === Medical Therapy ===
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| *The mainstay of therapy for phyllodes tumor is [medical therapy 1] and [medical therapy 2].
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| === Surgery ===
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| *Surgery is the mainstay of therapy for phyllodes tumor.
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| *[Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of phyllodes tumor.
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| *[Surgical procedure] can only be performed for patients with [disease stage] phyllodes tumor.
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| === Prevention ===
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| *Effective measures for the primary prevention of phyllodes tumor include periodical self-breast examination, and routine mammography.
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| *Once diagnosed and successfully treated, patients with phyllodes tumor are followed-up periodically.
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| *Follow-up testing, includes: ultrasound examination.
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| ==References==
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| {{Reflist|2}}
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| [[Category:Oncology]]
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