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| __NOTOC__
| | #REDIRECT [[Breast cancer]] |
| {{Infobox_Disease |
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| Name = Phyllodes tumor |
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| Image = |
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| Caption = |
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| DiseasesDB = 3396 |
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| ICD10 = {{ICD10|C|50||c|50}}, {{ICD10|D|24||d|10}}, {{ICD10|D|48|6|d|37}} |
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| ICD9 = {{ICD9|217 }} |
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| ICDO = M9020 |
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| OMIM = |
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| MedlinePlus = |
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| eMedicineSubj = |
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| eMedicineTopic = |
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| MeshID = D003557 |
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| }}
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| {{SI}}
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| {{CMG}}
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| {{SK}} Phylloides tumor
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| ==Overview==
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| '''Phyllodes tumors''' (from [[Greek language|Greek]]: ''phullon'' leaf), are typically large, fast growing masses that form from the periductal [[stroma]] of the [[breast]]. They account for less than 1% of all breast [[Neoplasia|neoplasms]].
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| ==Pathophysiology==
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| Phyllodes tumors are a [[fibroepithelial tumor]] composed of an epithelial and a cellular stromal component. They may be considered [[benign]], borderline, or [[malignant]] (cystosarcoma phyllodes or cystosarcoma phylloides) depending on histologic features including stromal cellularity, infiltration at the tumor's edge, and [[mitoses|mitotic activity]].
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| Phyllodes tumors are considered to be on a spectrum of disease<ref>{{cite journal |author=Deen SA, McKee GT, Kissin MW |title=Differential cytologic features of fibroepithelial lesions of the breast |journal=Diagn. Cytopathol. |volume=20 |issue=2 |pages=53-6 |year=1999 |pmid=9951596 |doi=}}</ref> that consists of [[fibroadenoma]], fibroadenoma variant and benign phyllodes. Some would extend the spectrum to include malignant phyllodes tumors and frank [[sarcoma]].
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| ==Differentiating Phyllodes tumor from other Diseases==
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| Phyllodes tumor should be differentiated from:
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| * [[Fibroadenoma]]
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| ==Epidemiology and Demographics==
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| ===Age===
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| Occurrence is most common between the ages of 40 and 50, prior to the [[menopause]]. This is about 15 years older than the typical age of patients with [[fibroadenoma]], a condition with which Phyllodes tumors may be confused.
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| ===Gender===
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| Phyllodes tumor is predominantly a tumor of adult women, with very few examples reported in adolescents.
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| ==Treatment==
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| ===Surgery===
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| The common treatment for phyllodes is [[wide local excision]]. Most patients are cured with [[surgery]]; the risk of developing local recurrence or [[metastasis|metastases]] is related to the histologic grade, according to the above-named features.
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| ==References==
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| {{Reflist|2}}
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| {{Soft tissue tumors and sarcomas}}
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| {{Breast neoplasia}}
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| [[bs:Filoidni tumor dojke]]
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| [[vi:Bướu diệp thể vú]]
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| [[Category:Disease]]
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| [[Category:Oncology]]
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| [[Category:Oncology stub]]
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