Desmoid tumor future or investigational therapies: Difference between revisions
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==Overview== | ==Overview== | ||
[[Angiogenesis inhibitor|Angiogenesis inhibitors]] and different [[chemotherapy agents]] are under [[Investigational new drug|investigation]] nowadays which might prove fruitful for treatment of [[Desmoid tumor|desmoid tumors]] in future. Furthermore, [[Mutation|mutational]] [[analysis]] for [[Beta-catenin|beta-catenin gene]] may soon be used to predict the recurrence risk and to aid in designing the individual therapies. | |||
==Future or Investigational therapies== | ==Future or Investigational therapies== | ||
*Following investigational therapies might prove fruitful in future for treatment of desmoid tumors: | *Following [[Investigational new drug|investigational therapies]] might prove fruitful in future for treatment of [[Desmoid tumor|desmoid tumors]]: | ||
===Angiogenesis inhibitors=== | ===Angiogenesis inhibitors=== | ||
*Newer substances | *Newer substances which block the formation of new [[blood vessels]] feeding the [[tumors]] are under [[Investigational New Drug|investigation]] and may be able to prevent the [[tumor]] [[growth]] in future | ||
===Chemotherapy agents=== | ===Chemotherapy agents=== | ||
* | *Several [[Chemotherapy agents|chemotherapy drugs]], or combination of [[drugs]] are being tested by researchers, that could prove to be most effective in treating [[Desmoid tumor|desmoid tumors]] to avoid radical management via [[surgery]] | ||
===Mutations in the gene for beta-catenin== | ===Mutations in the gene for beta-catenin=== | ||
* | *[[Beta-catenin]] [[gene]] [[mutations]] have been found to commonly occur in [[desmoid tumor]] | ||
*Mutation analysis may | *[[Mutation|Mutational]] [[analysis]] may be used soon in order to predict the recurrence risk and to aid in designing the individual therapies | ||
==Source== | ==Source== | ||
*Information on current clinical trials is posted on the Internet at www.clinicaltrials.gov | *Information on current clinical trials is posted on the Internet at: | ||
*National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/desmoid-tumor/ | **https://www.clinicaltrials.gov/ | ||
**National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/desmoid-tumor/ | |||
==Reference== | ==Reference== | ||
Latest revision as of 16:08, 13 March 2019
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Desmoid tumor Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]
Overview
Angiogenesis inhibitors and different chemotherapy agents are under investigation nowadays which might prove fruitful for treatment of desmoid tumors in future. Furthermore, mutational analysis for beta-catenin gene may soon be used to predict the recurrence risk and to aid in designing the individual therapies.
Future or Investigational therapies
- Following investigational therapies might prove fruitful in future for treatment of desmoid tumors:
Angiogenesis inhibitors
- Newer substances which block the formation of new blood vessels feeding the tumors are under investigation and may be able to prevent the tumor growth in future
Chemotherapy agents
- Several chemotherapy drugs, or combination of drugs are being tested by researchers, that could prove to be most effective in treating desmoid tumors to avoid radical management via surgery
Mutations in the gene for beta-catenin
- Beta-catenin gene mutations have been found to commonly occur in desmoid tumor
- Mutational analysis may be used soon in order to predict the recurrence risk and to aid in designing the individual therapies
Source
- Information on current clinical trials is posted on the Internet at:
- https://www.clinicaltrials.gov/
- National Organization for Rare Disorders (NORD) https://rarediseases.org/rare-diseases/desmoid-tumor/