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{{Choriocarcinoma}}
{{Gestational trophoblastic neoplasia}}
{{CMG}}
{{CMG}}{{AE}}{{MD}}{{Sab}}
 
 
==Overview==
==Overview==
Gestational trophoblastic neoplasia patients can present with history of previous pregnancies including [[hydatidiform mole]] ([[Hydatidiform mole|molar pregnancy]]) and [[miscarriage]], history of previous [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]], and [[Medical sign|signs]] and [[Symptom|symptoms]] that may suggest [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]. Symptoms of choriocarcinoma include [[vaginal bleeding]], passing of [[Tissue (biology)|tissue]] resembling a “bunch of grapes” from the [[vagina]], and [[Abdomen|abdominal]] distension.
==History==
When obtaining history from a [[patient]] with suspected gestational trophoblastic neoplasia, specific areas of focus include:
* History of previous [[pregnancies]], including [[hydatidiform mole]] ([[Hydatidiform mole|molar pregnancy]]) and [[miscarriage]]
* History of previous [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]
* [[Reproductive system|Reproductive]] factors that may increase the risk of [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]
* A family history of [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]
* [[Medical sign|Signs]] and [[Symptom|symptoms]] that may suggest [[Gestational trophoblastic disease|gestational trophoblastic disease (GTD)]]


==History and Symptoms==
==Symptoms==
* [[vaginal bleeding]]
===Early Symptoms of Gestational Trophoblastic Neoplasia===
* [[shortness of breath]]
* [[Vaginal bleeding]]<ref name="xxx">Signs and symptoms of gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/signs-and-symptoms/?region=ns Accessed on October 10, 2015</ref>
* [[hemoptysis]] (coughing up blood)
* [[Nausea]] and [[vomiting]]
* [[chest pain]]
* Passing of [[Tissue (biology)|tissue]] resembling a “bunch of grapes” from the [[vagina]]
 
* Absent [[fetal]] movement during [[pregnancy]]
Signs and symptoms of gestational trophoblastic disease
* [[Abdomen|Abdominal]] distension
 
===Rare Symptoms of Gestational Trophoblastic Neoplasia===
A sign is something that can be observed and recognized by a doctor or healthcare professional (for example, a rash). A symptom is something that only the person experiencing it can feel and know (for example, pain or tiredness). Some women with gestational trophoblastic disease (GTD) do not experience signs and symptoms because blood tests and ultrasound during prenatal care find most types of GTD early, before it causes any signs or symptoms.
* [[Headache]]
 
* [[Edema ]]of the [[Hand|hands]] and feet
Signs and symptoms of GTD include:
* [[Abdomen|Abdominal]] or [[Pelvis|pelvic]] pain
 
* [[Vaginal discharge]]
vaginal bleeding
* Overactive [[thyroid gland]] ([[hyperthyroidism]]) that causes:
swelling of the abdomen
:* [[Tachycardia]]
With a hydatidiform mole, the abdomen and uterus may grow at a much faster rate than with a normal pregnancy.
:* [[Sweating]]
 
:* Shaking
ovarian cysts (luteoma)
:* Heat intolerance
nausea and vomiting
:* [[Fever]]
Some women have a condition called hyperemesis gravidarum, which causes nausea and vomiting that is often much worse than what may occur during a normal pregnancy.
===Late Symptoms of Gestational Trophoblastic Neoplasia===
 
* [[Hemoptysis]]
passing of  tissue resembling a “bunch of grapes” from the vagina
* Dry [[cough]]
lack of fetal movement during pregnancy
* [[Chest pain]]
 
* Trouble [[breathing]]
Rare signs and symptoms
* [[Headache]]
 
* [[Dizziness]]
Rare signs and symptoms of GTD are:
* [[Jaundice]]
 
* [[Paralysis]]
anemia (if bleeding is severe or lasts for a long time)
* [[Seizure]]
pre-eclampsia, a condition characterized by:
* [[Dysarthria]] and [[dysphasia]]
high blood pressure
* [[Visual system|Vision]] problems
abnormal amounts of protein in the urine
* [[Lump]] in the [[vagina]]
headache
swelling of the hands and feet
 
overactive thyroid gland (hyperthyroidism) that causes:
rapid heartbeat
warm skin
sweating
shaking
feeling “too hot”
 
abdominal or pelvic pain
vaginal discharge
fever
 
Late signs and symptoms
 
Late signs and symptoms occur as the cancer grows larger or spreads to other parts of the body, including other organs.
 
coughing up blood
dry cough
chest pain
trouble breathing
headache
dizziness
yellowing of the skin or eyes (jaundicejaundiceA condition in which the skin and whites of the eyes become yellow and urine is dark yellow.)
gradual loss of the ability to move a body part (paralysis)
seizure
trouble speaking
vision problems
lump in the vagina
 


==References==
==References==
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[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gynecology]]
[[Category:Surgery]]

Latest revision as of 20:06, 19 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]Sabawoon Mirwais, M.B.B.S, M.D.[3]

Overview

Gestational trophoblastic neoplasia patients can present with history of previous pregnancies including hydatidiform mole (molar pregnancy) and miscarriage, history of previous gestational trophoblastic disease (GTD), and signs and symptoms that may suggest gestational trophoblastic disease (GTD). Symptoms of choriocarcinoma include vaginal bleeding, passing of tissue resembling a “bunch of grapes” from the vagina, and abdominal distension.

History

When obtaining history from a patient with suspected gestational trophoblastic neoplasia, specific areas of focus include:

Symptoms

Early Symptoms of Gestational Trophoblastic Neoplasia

Rare Symptoms of Gestational Trophoblastic Neoplasia

Late Symptoms of Gestational Trophoblastic Neoplasia

References

  1. ↑ Signs and symptoms of gestational trophoblastic disease. Canadian Cancer Society. http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/signs-and-symptoms/?region=ns Accessed on October 10, 2015

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