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| __NOTOC__
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| {{Thyroid adenoma}}
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| {{CMG}}; {{AE}} {{Ammu}}
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| ==Overview==
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| ==Biopsy==
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| * One approach used to determine type of adenoma is fine needle biopsy (FNB), which some have described as the most cost-effective, sensitive and accurate test.<ref>
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| {{cite journal
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| | last = Hamberger
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| | first = B
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| | year = 1982
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| | title = Fine-needle aspiration biopsy of thyroid nodules. Impact on thyroid practice and cost of care
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| | journal = Am J Med
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| | volume = 73
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| | pages = 381–384
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| | pmid = 7124765
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| | doi=10.1016/0002-9343(82)90731-8
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| | issue=3
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| }}
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| </ref><ref>
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| {{cite journal
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| | last = Mazzaferri
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| | year = 1993
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| | title = Management of a Solitary Thyroid Nodule
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| | journal = N Engl J Med
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| | volume = 328
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| | pages = 553–9
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| | pmid = 8426623
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| | doi=10.1056/NEJM199302253280807
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| | issue=8
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| }}
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| </ref>
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| * FNB or ultrasound-guided FNA usually yields sufficient thyroid cells to assess the pathology, although in some cases, the suspected nodule may need to be removed surgically for pathological examination. The report may be done according to the [[Bethesda System for Reporting Thyroid Cytopathology]].
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| ===Key Biopsy Findings in Thyroid adenoma===
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| * Areas of hemorrhage, fibrosis, calcification, and cystic change, similar to what is found in multinodular goiters, are common in thyroid (follicular) adenoma, particularly in larger lesions.
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| * Encapsulated tumors without evidence of infiltration
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| ==Biopsy Exams of Thyroid adenoma==
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| <gallery>
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| Image:Follicular adenoma.png|Follicular adenoma of the thyroid gland
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| Image:Micropathology.jpg|Histology of the encapsulated tumor. (a) Photomicrograph showing an encapsulated tumor composed of cells arranged in microfollicular, glandular and trabecular patterns (hematoxylin and eosin; 100×). (b) High power photomicrograph showing the microfollicles containing inspissated colloid resembling hyaline globules and separated by eosinophilic extracellular hyaline material. (hematoxylin and eosin; 100×).<ref name=radio02>Image courtesy of Dr Frank Gaillard. [http://www.jmedicalcasereports.com/content/8/1/270] (original file[http://www.jmedicalcasereports.com/content/8/1/270‘’here’’]).[http://www.jmedicalcasereports.com/content/8/1/270/licence Creative Commons BY-SA-NC]</ref>
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| </gallery>
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| ==References==
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| {{reflist|2}}
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| {{WH}}
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| {{WS}}
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| [[Category:Disease]]
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| [[Category:Endocrinology]]
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