Acute myeloid leukemia physical examination: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| (21 intermediate revisions by 5 users not shown) | |||
| Line 2: | Line 2: | ||
{{Acute myeloid leukemia}} | {{Acute myeloid leukemia}} | ||
{{CMG}}; {{AE}} {{RT}} | {{CMG}}; {{AE}} {{RT}}, {{CLG}}, {{shyam}}; {{GRR}} {{Nat}} | ||
==Overview== | ==Overview== | ||
Common physical examination findings of acute myeloid leukemia include [[anemia]], [[fever]], [[pallor]], [[chloroma|leukemia cutis]], [[bruising]], [[petechia]]e, [[ecchymosis]], [[tachycardia]]. Neurologic symptoms can also occur, but these are rarer. | |||
==Physical Examination== | ==Physical Examination== | ||
===Appearance=== | |||
The patient may appear pale because of [[anemia]].<ref name="pmid26137050">{{cite journal| author=Zhang Z, Zou J, Li Y, Liu Z, Xu R, Tian W et al.| title=Clinical characteristics and laboratory analyses of acute myeloid leukemia with t(16;21)(p11;q22). | journal=Oncol Lett | year= 2015 | volume= 9 | issue= 5 | pages= 2244-2248 | pmid=26137050 | doi=10.3892/ol.2015.3051 | pmc=4467340 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26137050 }} </ref> | |||
===Vitals=== | |||
* [[Fever]] | |||
* [[Tachycardia]] | |||
* [[Tachypnea]] | |||
* [[Hypotension]] | |||
===Skin=== | ===Skin=== | ||
* [[Pallor]] | * [[Pallor]]<ref name="pmid26137050">{{cite journal| author=Zhang Z, Zou J, Li Y, Liu Z, Xu R, Tian W et al.| title=Clinical characteristics and laboratory analyses of acute myeloid leukemia with t(16;21)(p11;q22). | journal=Oncol Lett | year= 2015 | volume= 9 | issue= 5 | pages= 2244-2248 | pmid=26137050 | doi=10.3892/ol.2015.3051 | pmc=4467340 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26137050 }} </ref> | ||
* [[Chloroma|Leukemia cutis]] | * [[Chloroma|Leukemia cutis]] | ||
* [[Bruising]] | * [[Bruising]] | ||
* [[Petechia]]e (flat, pin-head sized spots under the skin caused by bleeding) | * [[Petechia]]e (flat, pin-head sized spots under the skin caused by bleeding) | ||
* [[Ecchymosis]] | |||
===Head=== | |||
* [[Lymphadenopathy]] | |||
* Bleeding and swollen gums | |||
===Nose=== | |||
* [[Bleeding]] | |||
===Heart=== | |||
* Flow murmurs due to [[anemia]] | |||
===Abdomen=== | ===Abdomen=== | ||
* [[Splenomegaly]] | * [[Splenomegaly]] | ||
* [[Hepatomegaly]] | |||
* Flank hemorrhage | |||
* Gastrointestinal bleeding | |||
===Extremities=== | |||
* Bone tenderness | |||
* Joint tenderness | |||
===Neurologic=== | |||
* Altered mental status if there is central nervous system involvement<ref name="pmid17924103">{{cite journal| author=Laningham FH, Kun LE, Reddick WE, Ogg RJ, Morris EB, Pui CH| title=Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae. | journal=Neuroradiology | year= 2007 | volume= 49 | issue= 11 | pages= 873-88 | pmid=17924103 | doi=10.1007/s00234-007-0300-7 | pmc=2386669 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17924103 }} </ref> | |||
* Nuchal rigidity if there is leptomeningeal involvement | |||
* Headache if leukostasis is present | |||
* Blurred vision<ref name="pmid27668104">{{cite journal| author=Patel SA| title=Acute Myeloid Leukemia Relapse Presenting as Complete Monocular Vision Loss due to Optic Nerve Involvement. | journal=Case Rep Hematol | year= 2016 | volume= 2016 | issue= | pages= 3794284 | pmid=27668104 | doi=10.1155/2016/3794284 | pmc=5030445 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27668104 }} </ref> | |||
==References== | ==References== | ||
| Line 21: | Line 55: | ||
{{Hematology}} | {{Hematology}} | ||
{{Hematological malignancy histology}} | {{Hematological malignancy histology}} | ||
[[Category:Hematology]] | |||
[[Category:Types of cancer]] | |||
[[Category:Leukemia]] | |||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Hematology]] | |||
[[Category:Immunology]] | |||
Latest revision as of 13:04, 11 April 2019
|
Acute myeloid leukemia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Acute myeloid leukemia physical examination On the Web |
|
American Roentgen Ray Society Images of Acute myeloid leukemia physical examination |
|
Risk calculators and risk factors for Acute myeloid leukemia physical examination |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2], Carlos A Lopez, M.D. [3], Shyam Patel [4]; Grammar Reviewer: Natalie Harpenau, B.S.[5]
Overview
Common physical examination findings of acute myeloid leukemia include anemia, fever, pallor, leukemia cutis, bruising, petechiae, ecchymosis, tachycardia. Neurologic symptoms can also occur, but these are rarer.
Physical Examination
Appearance
The patient may appear pale because of anemia.[1]
Vitals
Skin
- Pallor[1]
- Leukemia cutis
- Bruising
- Petechiae (flat, pin-head sized spots under the skin caused by bleeding)
- Ecchymosis
Head
- Lymphadenopathy
- Bleeding and swollen gums
Nose
Heart
- Flow murmurs due to anemia
Abdomen
- Splenomegaly
- Hepatomegaly
- Flank hemorrhage
- Gastrointestinal bleeding
Extremities
- Bone tenderness
- Joint tenderness
Neurologic
- Altered mental status if there is central nervous system involvement[2]
- Nuchal rigidity if there is leptomeningeal involvement
- Headache if leukostasis is present
- Blurred vision[3]
References
- ↑ 1.0 1.1 Zhang Z, Zou J, Li Y, Liu Z, Xu R, Tian W; et al. (2015). "Clinical characteristics and laboratory analyses of acute myeloid leukemia with t(16;21)(p11;q22)". Oncol Lett. 9 (5): 2244–2248. doi:10.3892/ol.2015.3051. PMC 4467340. PMID 26137050.
- ↑ Laningham FH, Kun LE, Reddick WE, Ogg RJ, Morris EB, Pui CH (2007). "Childhood central nervous system leukemia: historical perspectives, current therapy, and acute neurological sequelae". Neuroradiology. 49 (11): 873–88. doi:10.1007/s00234-007-0300-7. PMC 2386669. PMID 17924103.
- ↑ Patel SA (2016). "Acute Myeloid Leukemia Relapse Presenting as Complete Monocular Vision Loss due to Optic Nerve Involvement". Case Rep Hematol. 2016: 3794284. doi:10.1155/2016/3794284. PMC 5030445. PMID 27668104.