Carcinoid syndrome history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Symptoms of carcinoid tumor include [[flushing]], [[diarrhea]], [[abdominal cramps]], [[wheezing]], and [[cough]]. | Symptoms of [[carcinoid tumor]] include [[flushing]], [[diarrhea]], [[abdominal cramps]], [[wheezing]], and [[cough]]. | ||
==History== | ==History== | ||
When evaluating a patient for carcinoid syndrome, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough past medical history review. Other specific areas of focus when obtaining the history are: | When evaluating a patient for [[Carcinoid Syndrome|carcinoid syndrome]], you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated [[symptoms]], and a thorough [[past medical history]] review. Other specific areas of focus when obtaining the history are: | ||
*Review of any family history of predisposing genetic disorders such as [[multiple endocrine neoplasia type 1]] or [[neurofibromatosis type 1]]. | *Review of any family history of predisposing genetic disorders such as [[multiple endocrine neoplasia type 1]] or [[neurofibromatosis type 1]]. | ||
==Symptoms== | ==Symptoms== | ||
===Carcinoid Syndrome=== | ===Carcinoid Syndrome=== | ||
Common symptoms of carcinoid syndrome include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of [[Carcinoid Syndrome|carcinoid syndrome]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
* [[Flushing (physiology)|Flushing]] | * [[Flushing (physiology)|Flushing]] | ||
* [[Diarrhea]] | * [[Diarrhea]] | ||
| Line 23: | Line 23: | ||
*[[Hirsutism]] | *[[Hirsutism]] | ||
*[[Weakness]] | *[[Weakness]] | ||
This constellation of symptoms is called carcinoid syndrome or (if acute) carcinoid crisis. Occasionally, [[hemorrhage]] or pressure effects of the tumor are the presenting symptoms. | This constellation of [[symptoms]] is called [[Carcinoid Syndrome|carcinoid syndrome]] or (if [[acute]]) [[carcinoid crisis]]. Occasionally, [[hemorrhage]] or pressure effects of the [[tumor]] are the presenting [[symptoms]]. | ||
===Gastrointestinal Carcinoid Tumor=== | ===Gastrointestinal Carcinoid Tumor=== | ||
Common symptoms of gastrointestinal carcinoid tumor include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of [[gastrointestinal]] [[carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*[[Abdominal pain]] | *[[Abdominal pain]] | ||
*[[Diarrhea]] | *[[Diarrhea]] | ||
| Line 32: | Line 32: | ||
*[[Rash]] | *[[Rash]] | ||
*[[Gastrointestinal bleeding]] | *[[Gastrointestinal bleeding]] | ||
*[[Pellagra]], which causes scale-like skin sores, [[diarrhea]], and mental disturbances | *[[Pellagra]], which causes scale-like [[skin]] [[sores]], [[diarrhea]], and [[mental]] disturbances | ||
*[[Melena]] | *[[Melena]] | ||
*[[Nausea]] | *[[Nausea]] | ||
| Line 39: | Line 39: | ||
===Duodenal Carcinoid Tumor=== | ===Duodenal Carcinoid Tumor=== | ||
Common symptoms of duodenal carcinoid tumor due to gastrin overproduction include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of duodenal [[Carcinoid tumors|carcinoid tumor]] due to [[gastrin]] overproduction include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*[[Nausea]] | *[[Nausea]] | ||
*[[Vomiting]] | *[[Vomiting]] | ||
| Line 45: | Line 45: | ||
*[[Hemorrhage]] from multiple and recurrent [[peptic ulcers]] | *[[Hemorrhage]] from multiple and recurrent [[peptic ulcers]] | ||
*[[Gastroesophageal reflux]] | *[[Gastroesophageal reflux]] | ||
*[[Diarrhea]] from hypergastrinemia | *[[Diarrhea]] from [[hypergastrinemia]] | ||
===Jejunal and Ileal Carcinoid Tumor=== | ===Jejunal and Ileal Carcinoid Tumor=== | ||
Common symptoms of jejunal and ileal carcinoid tumor include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of [[Jejunum|jejunal]] and [[Ileum|ileal]] [[Carcinoid tumors|carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*Small intestinal obstruction | *[[Small intestinal]] [[obstruction]] | ||
*[[Hemorrhage]] | *[[Hemorrhage]] | ||
* | *Intermitten[[Crampy|t crampy]] [[abdominal pain]] | ||
*[[Weight loss]] | *[[Weight loss]] | ||
| Line 68: | Line 68: | ||
===Colorectal carcinoid Tumor=== | ===Colorectal carcinoid Tumor=== | ||
Common symptoms of colorectal carcinoid tumor include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common symptoms of [[colorectal]] [[Carcinoid tumors|carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*[[Hemorrhage]] | *[[Hemorrhage]] | ||
| Line 76: | Line 76: | ||
===Lung Carcinoid Tumor=== | ===Lung Carcinoid Tumor=== | ||
Common symptoms of lung carcinoid tumor include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | Common [[symptoms]] of [[lung]] [[Carcinoid tumors|carcinoid tumor]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*Post-obstructive [[pneumonia]] | *Post-obstructive [[pneumonia]] | ||
*[[Wheezing]] | *[[Wheezing]] | ||
| Line 82: | Line 82: | ||
===Thymic Carcinoid=== | ===Thymic Carcinoid=== | ||
Thymic carcinoid causes [[Cushing syndrome]] as a result of [[adrenocorticotropic hormone]] secretion by the tumor. Common symptoms of [[Cushing syndrome]] include:<ref name=symptoms>Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | [[Thymic]] [[carcinoid]] causes [[Cushing syndrome]] as a result of [[adrenocorticotropic hormone]] secretion by the [[tumor]]. Common symptoms of [[Cushing syndrome]] include:<ref name="symptoms">Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq</ref> | ||
*[[Obesity|Central obesity]] | *[[Obesity|Central obesity]] | ||
*[[Moon face]] | *[[Moon face]] | ||
Latest revision as of 16:49, 19 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
Symptoms of carcinoid tumor include flushing, diarrhea, abdominal cramps, wheezing, and cough.
History
When evaluating a patient for carcinoid syndrome, you should take a detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough past medical history review. Other specific areas of focus when obtaining the history are:
- Review of any family history of predisposing genetic disorders such as multiple endocrine neoplasia type 1 or neurofibromatosis type 1.
Symptoms
Carcinoid Syndrome
Common symptoms of carcinoid syndrome include:[1]
- Flushing
- Diarrhea
- Wheezing
- Abdominal cramping
- Leg edema
- Shortness of breath
- Palpitations
- Weight gain
- Hirsutism
- Weakness
This constellation of symptoms is called carcinoid syndrome or (if acute) carcinoid crisis. Occasionally, hemorrhage or pressure effects of the tumor are the presenting symptoms.
Gastrointestinal Carcinoid Tumor
Common symptoms of gastrointestinal carcinoid tumor include:[1]
- Abdominal pain
- Diarrhea
- Facial flushing
- Rash
- Gastrointestinal bleeding
- Pellagra, which causes scale-like skin sores, diarrhea, and mental disturbances
- Melena
- Nausea
- Vomiting
- Jaundice
Duodenal Carcinoid Tumor
Common symptoms of duodenal carcinoid tumor due to gastrin overproduction include:[1]
- Nausea
- Vomiting
- Abdominal pain
- Hemorrhage from multiple and recurrent peptic ulcers
- Gastroesophageal reflux
- Diarrhea from hypergastrinemia
Jejunal and Ileal Carcinoid Tumor
Common symptoms of jejunal and ileal carcinoid tumor include:[1]
- Intermittent crampy abdominal pain
Colorectal carcinoid Tumor
Common symptoms of colorectal carcinoid tumor include:[1]
Lung Carcinoid Tumor
Common symptoms of lung carcinoid tumor include:[1]
Thymic Carcinoid
Thymic carcinoid causes Cushing syndrome as a result of adrenocorticotropic hormone secretion by the tumor. Common symptoms of Cushing syndrome include:[1]
- Central obesity
- Moon face
- Diaphoresis
- Insomnia
- Decreased libido
- Impotence
- Amenorrhoea
- Infertility
- Mood disorders[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Signs and symptoms of carcinoid syndrome. National Cancer Institute. http://www.cancer.gov/types/gi-carcinoid-tumors/patient/gi-carcinoid-treatment-pdq
- ↑ Yudofsky, Stuart C. (2007). The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences (5th ed.). American Psychiatric Pub, Inc. ISBN 1585622397. Unknown parameter
|coauthors=ignored (help)