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| '''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
| | #REDIRECT [[Sexcord/ stromal ovarian tumors]] |
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| {{DiseaseDisorder infobox |
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| Name = Granulosa cell tumour |
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| ICD10 = {{ICD10|C|56||c|51}} |
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| ICD9 = {{ICD9|183}} |
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| ICDO = 8620 |
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| Image = |
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| Caption = |
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| OMIM = |
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| MedlinePlus = |
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| DiseasesDB = |
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| }}
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| {{SI}}
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| {{EH}}
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| ==Overview==
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| '''Granulosa cell tumours''' (or '''granulosa-theca''') are part of the [[sex cord-stromal tumour]] group of [[Ovarian cancer|ovarian neoplasm]]s.
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| The peak age at which they occur is 50-55 years, but they may occur at any age.
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| ==Clinical presentation==
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| [[Estrogen]]s are produced by ''functioning'' tumours, and the clinical presentation depends on the patient's age.
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| * If the patient is [[postmenopausal]], she usually presents with [[abnormal uterine bleeding]].
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| * If the patient is of reproductive age, she would present with [[menometrorrhagia]].
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| * If the patient has not undergone [[puberty]], isosexual-pseudo-precocity may be seen.
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| ==Histology==
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| The most characteristic gross appearance is a smooth surfaced solid and cystic lesion with the cysts filled with [[blood]].
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| Hemoperitoneum is an infrequent but classical presentation.
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| A large variety of [[histology|histological]] presentations exists, but they have two key features:
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| #[[Call-Exner bodies]] ([[granulosa cell]]s arranged haphazardly around a space containing [[eosinophilic]] fluid); ''and''
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| #Pale uniform nuclei, often with grooves
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| ==See also==
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| * [[granulosa cell]]
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| * [[Sertoli-Leydig cell tumour]]
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| ==External links==
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| * {{GPnotebook|-46858173}}
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| * [http://www-medlib.med.utah.edu/WebPath/FEMHTML/FEM057.html Photo of tumor]
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| * [http://www.bioscience.org/atlases/tumpath/freprod/ovary/9/micro.htm Slides]
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| * [http://www.indiandoctors.com/OBGYN/Malignancy/Malignancy_02.htm indiandoctors.com]
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| {{Epithelial neoplasms}}
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| {{SIB}}
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| [[Category:Gynecology]]
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| [[Category:Types of cancer]]
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| [[Category:Oncology]]
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| [[Category:Mature chapter]]
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