Familial mediterranean fever laboratory Findings: Difference between revisions
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==Overview== | ==Overview== | ||
An [[acute phase response]] is present during attacks, with high [[C-reactive protein]] levels, an elevated [[white blood cell]] count and other markers of [[inflammation]]. In patients with a long history of attacks, monitoring the [[renal function]] is of importance in predicting [[chronic renal failure]].<ref name="Livneh">Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref> | An [[acute phase response]] is present during attacks, with high [[C-reactive protein]] levels, an elevated [[white blood cell]] count and other markers of [[inflammation]]. | ||
==Laboratory Findings== | |||
*There are no [[diagnostic]] [[laboratory]] findings associated with [[Familial mediterranean fever|familial Mediterranean fever]]. However, this [[disorder]] is associated with an increase in [[acute phase reactant]] such as:<ref name="pmid11779767">{{cite journal |vauthors=Korkmaz C, Ozdogan H, Kasapçopur O, Yazici H |title=Acute phase response in familial Mediterranean fever |journal=Ann. Rheum. Dis. |volume=61 |issue=1 |pages=79–81 |date=January 2002 |pmid=11779767 |pmc=1753891 |doi=10.1136/ard.61.1.79 |url=}}</ref> | |||
**[[Erythrocyte sedimentation rate]] ([[ESR]]) | |||
**[[C-reactive protein]] ([[CRP]]) | |||
**[[fibrinogen]] | |||
**[[Serum amyloid A]] ([[Serum amyloid A protein|SAA]]) | |||
*[[Urinary]] [[sediment]] of [[patients]] with [[FMF]] may show [[hematuria]].<ref name="KallinichAktay2015">{{cite journal|last1=Kallinich|first1=Tilmann|last2=Aktay|first2=Nuray|last3=Ozen|first3=Seza|title=Special Aspects of Familial Mediterranean Fever in Childhood|volume=3|year=2015|pages=31–45|issn=2282-6505|doi=10.1007/978-3-319-14615-7_3}}</ref> | |||
**In [[Patient|patients]] with a long history of attacks, monitoring the [[renal function]] is of importance in predicting [[chronic renal failure]].<ref name="Livneh">Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref> | |||
==References== | ==References== | ||
Latest revision as of 16:26, 10 June 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
An acute phase response is present during attacks, with high C-reactive protein levels, an elevated white blood cell count and other markers of inflammation.
Laboratory Findings
- There are no diagnostic laboratory findings associated with familial Mediterranean fever. However, this disorder is associated with an increase in acute phase reactant such as:[1]
- Urinary sediment of patients with FMF may show hematuria.[2]
- In patients with a long history of attacks, monitoring the renal function is of importance in predicting chronic renal failure.[3]
References
- ↑ Korkmaz C, Ozdogan H, Kasapçopur O, Yazici H (January 2002). "Acute phase response in familial Mediterranean fever". Ann. Rheum. Dis. 61 (1): 79–81. doi:10.1136/ard.61.1.79. PMC 1753891. PMID 11779767.
- ↑ Kallinich, Tilmann; Aktay, Nuray; Ozen, Seza (2015). "Special Aspects of Familial Mediterranean Fever in Childhood". 3: 31–45. doi:10.1007/978-3-319-14615-7_3. ISSN 2282-6505.
- ↑ Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. Baillieres Best Pract Res Clin Rheumatol 2000;14(3):477-98. PMID 10985982.