Medullary thyroid cancer screening: Difference between revisions

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==Overview==
==Overview==
According to the American Society of Clinical Oncology, screening for medullary thyroid cancer by ''RET'' gene testing is recommended for children with increased risk of medullary thyroid cancer.
According to the US preventive service task force, [[screening]] for medullary thyroid cancer is not recommended.
==Screening==
==Screening==
{|
* According to the US preventive service task force, [[screening]] for medullary thyroid cancer is not recommended.<ref name="urlFinal Recommendation Statement: Thyroid Cancer: Screening - US Preventive Services Task Force">{{cite web |url=https://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/thyroid-cancer-screening1 |title=Final Recommendation Statement: Thyroid Cancer: Screening - US Preventive Services Task Force |format= |work= |accessdate=}}</ref>
|-
| valign=top |
{| style="border: 0px; font-size: 90%; margin: 3px; width: 500px;" align=center
! style="padding: 0 5px; font-size: 100%; background: #4479BA" align=center | ''{{fontcolor|#FFF|Screening for medullary thyroid cancer}}''
|-
! style="padding: 0 5px; font-size: 95%; background:  #DCDCDC" align=left | '''The DNA-based testing of the c-RET gene'''
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Children with c-RET codon 609, 768, 790, 791, 804 and 891 mutations are more prone to less aggressive and slowly growing medullary thyroid cancer and a periodic [[pentagastrin]]-stimulated test with [[thyroidectomy]], at the first abnormal test result, has been recommended.<ref> Multiple endocrine neoplasia type2. Orphanet (30.10.2015). http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=653 Accessed on October, 30, 2015</ref>
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Individuals with c-RET codon 609, 611, 618, 620, 630, 634, 790, V804L, 883, 918 or 922 mutations should be routinely screened for [[pheochromocytoma]] by annual determinations of fractionated urinary and free plasma [[metanephrine]]s and [[catecholamine]]s.
|-
| style="padding: 5px 5px; background: #F5F5F5;" colspan="2"|<small>Adapted from Marquard J, Eng C. Multiple Endocrine Neoplasia Type 2. 1999 Sep 27 [Updated 2015 Jun 25]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2015. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1257/<ref>{{Cite journal| author = [[Jessica Marquard]] & [[Charis Eng]]
| title = Multiple Endocrine Neoplasia Type 2
| year = 1993
| month =  
| pmid = 020301434
}}</ref>
|}
==Reference==
==Reference==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Endocrine system]]
[[Category:Endocrinology]]
[[Category:Otolaryngology]]
[[Category:Disease]]
[[Category:Genetic disorders]]
[[Category:Types of cancer]]
[[Category:Hereditary cancers]]

Latest revision as of 18:26, 8 August 2019

Medullary thyroid cancer Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Medullary thyroid cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

According to the US preventive service task force, screening for medullary thyroid cancer is not recommended.

Screening

  • According to the US preventive service task force, screening for medullary thyroid cancer is not recommended.[1]

Reference

  1. ↑ "Final Recommendation Statement: Thyroid Cancer: Screening - US Preventive Services Task Force".
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