Waldenström's macroglobulinemia MRI: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Waldenström's macroglobulinemia}} | {{Waldenström's macroglobulinemia}} | ||
{{CMG}}{{AE}}{{RAK}} | {{CMG}}{{AE}}{{S.M.}}{{RAK}} | ||
==Overview== | ==Overview== | ||
There are no specific MRI findings associated with Waldenström macroglobulinemia. | There are no specific [[MRI]] findings [[Association (statistics)|associated]] with [[Waldenström's macroglobulinemia|Waldenstrom's macroglobulinemia]]. However, [[MRI]] of the [[brain]], [[spinal cord]] and [[orbits]] is especially important while [[Assessment and Plan|assessing]] [[hyperviscosity]] and for [[Diagnose|diagnosing]] [[Bing-Neel syndrome]]. | ||
==MRI | ==MRI== | ||
There are no specific MRI findings associated with Waldenström macroglobulinemia. However, MRI of the brain and orbits is important when assessing for hyperviscosity in the presence of high IgM paraprotein in the blood. | *There are no specific [[MRI]] findings [[Association (statistics)|associated]] with [[Waldenström's macroglobulinemia|waldenstrom's macroglobulinemia]]. | ||
*However, [[MRI]] of the [[brain]], [[spinal cord]] and [[orbits]] is important when [[Assessment and Plan|assessing]] for [[hyperviscosity]] in the presence of high [[IgM]] [[paraprotein]] in the [[blood]] especially important when [[Diagnose|diagnosing]] [[Bing-Neel syndrome]].<ref name="pmid30228918">{{cite journal| author=O'Neil DS, Francescone MA, Khan K, Bachir A, O'Connor OA, Sawas A| title=A Case of Bing-Neel Syndrome Successfully Treated with Ibrutinib. | journal=Case Rep Hematol | year= 2018 | volume= 2018 | issue= | pages= 8573105 | pmid=30228918 | doi=10.1155/2018/8573105 | pmc=6136466 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30228918 }} </ref><ref name="pmid27758817">{{cite journal| author=Minnema MC, Kimby E, D'Sa S, Fornecker LM, Poulain S, Snijders TJ et al.| title=Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome. | journal=Haematologica | year= 2017 | volume= 102 | issue= 1 | pages= 43-51 | pmid=27758817 | doi=10.3324/haematol.2016.147728 | pmc=5210231 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27758817 }} </ref><ref name="pmid30279255">{{cite journal| author=Tallant A, Selig D, Wanko SO, Roswarski J| title=First-line ibrutinib for Bing-Neel syndrome. | journal=BMJ Case Rep | year= 2018 | volume= 2018 | issue= | pages= | pmid=30279255 | doi=10.1136/bcr-2018-226102 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30279255 }} </ref> | |||
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[[File:Mri diffuse gif.gif|thumb|250px|none|MRI brain coronal view shows diffuse meningeal enhancement in a patient with Bing-Neel syndrome.[https://openi.nlm.nih.gov/detailedresult.php?img=PMC4837273_CRIHEM2016-3931709.002&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=69 Source: Halperin D. et al, Whipps Cross Hospital, London E11 1NR, UK.]]] | |||
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[[File:Bing neel mri.png|thumb|250px|none|Coronal T1-weighted (TR 600, TE 30) 3mm noncontrast sections through the inner ear in a patient with Waldenstrom macroglobulinemia with bilateral hearing loss. Arrows indicate hemorrhage within the labyrinth.[https://openi.nlm.nih.gov/detailedresult.php?img=PMC4891550_gr2&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=67 Source: Shibata DK. et al.]]] | |||
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[[File:MRI bing neel.png|thumb|250px|none| Axial T1-weighted (TR 700, TE 30) 3mm noncontrast sections through the petrous bone in a patient with Waldenstrom macroglobulinemia with bilateral hearing loss. Arrows indicate T1 shortening within the labyrinth.[https://openi.nlm.nih.gov/detailedresult.php?img=PMC4891550_gr1&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=66 Source: Shibata DK. et al.]]] | |||
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==References== | ==References== | ||
{{ | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Blood]] | [[Category:Blood]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Latest revision as of 18:56, 15 August 2019
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Waldenström's macroglobulinemia Microchapters |
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Differentiating Waldenström's macroglobulinemia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Waldenström's macroglobulinemia MRI On the Web |
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American Roentgen Ray Society Images of Waldenström's macroglobulinemia MRI |
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Directions to Hospitals Treating Waldenström's macroglobulinemia |
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Risk calculators and risk factors for Waldenström's macroglobulinemia MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Roukoz A. Karam, M.D.[3]
Overview
There are no specific MRI findings associated with Waldenstrom's macroglobulinemia. However, MRI of the brain, spinal cord and orbits is especially important while assessing hyperviscosity and for diagnosing Bing-Neel syndrome.
MRI
- There are no specific MRI findings associated with waldenstrom's macroglobulinemia.
- However, MRI of the brain, spinal cord and orbits is important when assessing for hyperviscosity in the presence of high IgM paraprotein in the blood especially important when diagnosing Bing-Neel syndrome.[1][2][3]
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References
- ↑ O'Neil DS, Francescone MA, Khan K, Bachir A, O'Connor OA, Sawas A (2018). "A Case of Bing-Neel Syndrome Successfully Treated with Ibrutinib". Case Rep Hematol. 2018: 8573105. doi:10.1155/2018/8573105. PMC 6136466. PMID 30228918.
- ↑ Minnema MC, Kimby E, D'Sa S, Fornecker LM, Poulain S, Snijders TJ; et al. (2017). "Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome". Haematologica. 102 (1): 43–51. doi:10.3324/haematol.2016.147728. PMC 5210231. PMID 27758817.
- ↑ Tallant A, Selig D, Wanko SO, Roswarski J (2018). "First-line ibrutinib for Bing-Neel syndrome". BMJ Case Rep. 2018. doi:10.1136/bcr-2018-226102. PMID 30279255.